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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ESYT2
Full Name:
Extended synaptotagmin-2
Alias:
Chr2Syt; E-Syt2; Extended synaptotagmin-like protein 2; FA62B; FAM62B; KIAA1228; Tcag7.562
Type:
Uncharacterized protein, membrane protein of FAM62 family
Mass (Da):
102357
Number AA:
921
UniProt ID:
A0FGR8
International Prot ID:
IPI00409635
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005086
PhosphoSite+
KinaseNET
Biological Process:
GO:0032012
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
N
R
D
A
A
L
S
S
H
R
H
P
G
C
Site 2
S11
N
R
D
A
A
L
S
S
H
R
H
P
G
C
A
Site 3
T23
G
C
A
Q
R
P
R
T
P
T
F
A
S
S
S
Site 4
T25
A
Q
R
P
R
T
P
T
F
A
S
S
S
Q
R
Site 5
S29
R
T
P
T
F
A
S
S
S
Q
R
R
S
A
F
Site 6
S30
T
P
T
F
A
S
S
S
Q
R
R
S
A
F
G
Site 7
S34
A
S
S
S
Q
R
R
S
A
F
G
F
D
D
G
Site 8
S50
F
P
G
L
G
E
R
S
H
A
P
G
S
R
L
Site 9
S55
E
R
S
H
A
P
G
S
R
L
G
A
R
R
R
Site 10
T65
G
A
R
R
R
A
K
T
A
R
G
L
R
G
H
Site 11
S82
R
G
A
G
A
G
L
S
R
P
G
S
A
R
A
Site 12
S86
A
G
L
S
R
P
G
S
A
R
A
P
S
P
P
Site 13
S91
P
G
S
A
R
A
P
S
P
P
R
P
G
G
P
Site 14
S152
L
L
A
W
C
R
R
S
R
G
L
K
A
L
R
Site 15
T220
I
E
K
L
F
R
E
T
I
E
P
A
V
R
G
Site 16
S233
R
G
A
N
T
H
L
S
T
F
S
F
T
K
V
Site 17
T234
G
A
N
T
H
L
S
T
F
S
F
T
K
V
D
Site 18
S236
N
T
H
L
S
T
F
S
F
T
K
V
D
V
G
Site 19
S271
I
I
L
D
L
Q
I
S
F
V
G
N
C
E
I
Site 20
Y285
I
D
L
E
I
K
R
Y
F
C
R
A
G
V
K
Site 21
T299
K
S
I
Q
I
H
G
T
M
R
V
I
L
E
P
Site 22
T402
Q
D
L
Q
G
K
D
T
Y
L
K
G
L
V
K
Site 23
Y403
D
L
Q
G
K
D
T
Y
L
K
G
L
V
K
G
Site 24
S412
K
G
L
V
K
G
K
S
D
P
Y
G
I
I
R
Site 25
Y415
V
K
G
K
S
D
P
Y
G
I
I
R
V
G
N
Site 26
S435
R
V
I
K
E
N
L
S
P
K
W
N
E
V
Y
Site 27
Y442
S
P
K
W
N
E
V
Y
E
A
L
V
Y
E
H
Site 28
Y447
E
V
Y
E
A
L
V
Y
E
H
P
G
Q
E
L
Site 29
T490
R
L
L
D
E
W
F
T
L
D
E
V
P
K
G
Site 30
T507
H
L
R
L
E
W
L
T
L
M
P
N
A
S
N
Site 31
T520
S
N
L
D
K
V
L
T
D
I
K
A
D
K
D
Site 32
S550
D
S
A
R
N
L
P
S
G
K
K
I
S
S
N
Site 33
S555
L
P
S
G
K
K
I
S
S
N
P
N
P
V
V
Site 34
S556
P
S
G
K
K
I
S
S
N
P
N
P
V
V
Q
Site 35
S573
V
G
H
K
A
Q
E
S
K
I
R
Y
K
T
N
Site 36
Y577
A
Q
E
S
K
I
R
Y
K
T
N
E
P
V
W
Site 37
T579
E
S
K
I
R
Y
K
T
N
E
P
V
W
E
E
Site 38
S621
G
N
L
K
V
P
L
S
Q
L
L
T
S
E
D
Site 39
T630
L
L
T
S
E
D
M
T
V
S
Q
R
F
Q
L
Site 40
S632
T
S
E
D
M
T
V
S
Q
R
F
Q
L
S
N
Site 41
S638
V
S
Q
R
F
Q
L
S
N
S
G
P
N
S
T
Site 42
S640
Q
R
F
Q
L
S
N
S
G
P
N
S
T
I
K
Site 43
S644
L
S
N
S
G
P
N
S
T
I
K
M
K
I
A
Site 44
S669
R
P
P
D
H
Q
H
S
A
Q
V
K
R
P
S
Site 45
S676
S
A
Q
V
K
R
P
S
V
S
K
E
G
R
K
Site 46
T684
V
S
K
E
G
R
K
T
S
I
K
S
H
M
S
Site 47
S685
S
K
E
G
R
K
T
S
I
K
S
H
M
S
G
Site 48
S688
G
R
K
T
S
I
K
S
H
M
S
G
S
P
G
Site 49
S691
T
S
I
K
S
H
M
S
G
S
P
G
P
G
G
Site 50
S693
I
K
S
H
M
S
G
S
P
G
P
G
G
S
N
Site 51
S699
G
S
P
G
P
G
G
S
N
T
A
P
S
T
P
Site 52
T701
P
G
P
G
G
S
N
T
A
P
S
T
P
V
I
Site 53
S704
G
G
S
N
T
A
P
S
T
P
V
I
G
G
S
Site 54
T705
G
S
N
T
A
P
S
T
P
V
I
G
G
S
D
Site 55
S711
S
T
P
V
I
G
G
S
D
K
P
G
M
E
E
Site 56
S736
G
L
H
D
L
G
R
S
S
S
S
L
L
A
S
Site 57
S737
L
H
D
L
G
R
S
S
S
S
L
L
A
S
P
Site 58
S738
H
D
L
G
R
S
S
S
S
L
L
A
S
P
G
Site 59
S739
D
L
G
R
S
S
S
S
L
L
A
S
P
G
H
Site 60
S743
S
S
S
S
L
L
A
S
P
G
H
I
S
V
K
Site 61
S748
L
A
S
P
G
H
I
S
V
K
E
P
T
P
S
Site 62
T753
H
I
S
V
K
E
P
T
P
S
I
A
S
D
I
Site 63
S755
S
V
K
E
P
T
P
S
I
A
S
D
I
S
L
Site 64
S758
E
P
T
P
S
I
A
S
D
I
S
L
P
I
A
Site 65
S761
P
S
I
A
S
D
I
S
L
P
I
A
T
Q
E
Site 66
T766
D
I
S
L
P
I
A
T
Q
E
L
R
Q
R
L
Site 67
T781
R
Q
L
E
N
G
T
T
L
G
Q
S
P
L
G
Site 68
S785
N
G
T
T
L
G
Q
S
P
L
G
Q
I
Q
L
Site 69
T793
P
L
G
Q
I
Q
L
T
I
R
H
S
S
Q
R
Site 70
S797
I
Q
L
T
I
R
H
S
S
Q
R
N
K
L
I
Site 71
S798
Q
L
T
I
R
H
S
S
Q
R
N
K
L
I
V
Site 72
S817
C
R
N
L
I
A
F
S
E
D
G
S
D
P
Y
Site 73
S821
I
A
F
S
E
D
G
S
D
P
Y
V
R
M
Y
Site 74
Y824
S
E
D
G
S
D
P
Y
V
R
M
Y
L
L
P
Site 75
Y828
S
D
P
Y
V
R
M
Y
L
L
P
D
K
R
R
Site 76
S836
L
L
P
D
K
R
R
S
G
R
R
K
T
H
V
Site 77
T841
R
R
S
G
R
R
K
T
H
V
S
K
K
T
L
Site 78
S844
G
R
R
K
T
H
V
S
K
K
T
L
N
P
V
Site 79
T847
K
T
H
V
S
K
K
T
L
N
P
V
F
D
Q
Site 80
S859
F
D
Q
S
F
D
F
S
V
S
L
P
E
V
Q
Site 81
S861
Q
S
F
D
F
S
V
S
L
P
E
V
Q
R
R
Site 82
T869
L
P
E
V
Q
R
R
T
L
D
V
A
V
K
N
Site 83
S882
K
N
S
G
G
F
L
S
K
D
K
G
L
L
G
Site 84
Y908
A
K
G
W
T
Q
W
Y
D
L
T
E
D
G
T
Site 85
T921
G
T
R
P
Q
A
M
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation