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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM62C
Full Name:
Extended synaptotagmin-3
Alias:
Chr3syt; E-Syt3
Type:
Uncharacterized membrane protein
Mass (Da):
100035
Number AA:
886
UniProt ID:
A0FGR9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
S
A
L
G
A
Q
R
T
P
G
P
E
L
R
L
Site 2
S28
P
G
P
E
L
R
L
S
S
Q
L
L
P
E
L
Site 3
S29
G
P
E
L
R
L
S
S
Q
L
L
P
E
L
C
Site 4
S152
E
P
K
I
R
E
K
S
I
H
L
R
T
F
T
Site 5
T157
E
K
S
I
H
L
R
T
F
T
F
T
K
L
Y
Site 6
T161
H
L
R
T
F
T
F
T
K
L
Y
F
G
Q
K
Site 7
Y164
T
F
T
F
T
K
L
Y
F
G
Q
K
C
P
R
Site 8
T188
T
C
N
R
R
R
V
T
V
D
L
Q
I
C
Y
Site 9
T253
P
H
L
Q
I
N
W
T
G
L
T
N
L
L
D
Site 10
S268
A
P
G
I
N
D
V
S
D
S
L
L
E
D
L
Site 11
T297
V
K
K
G
L
D
L
T
N
L
R
F
P
L
P
Site 12
S331
F
L
G
L
R
G
K
S
D
P
Y
A
K
V
S
Site 13
Y334
L
R
G
K
S
D
P
Y
A
K
V
S
I
G
L
Site 14
S346
I
G
L
Q
H
F
R
S
R
T
I
Y
R
N
L
Site 15
T348
L
Q
H
F
R
S
R
T
I
Y
R
N
L
N
P
Site 16
Y350
H
F
R
S
R
T
I
Y
R
N
L
N
P
T
W
Site 17
Y378
Q
D
L
E
V
D
L
Y
D
E
D
T
D
R
D
Site 18
T382
V
D
L
Y
D
E
D
T
D
R
D
D
F
L
G
Site 19
S390
D
R
D
D
F
L
G
S
L
Q
I
C
L
G
D
Site 20
T413
E
W
F
V
L
N
D
T
T
S
G
R
L
H
L
Site 21
S415
F
V
L
N
D
T
T
S
G
R
L
H
L
R
L
Site 22
S426
H
L
R
L
E
W
L
S
L
L
T
D
Q
E
V
Site 23
T435
L
T
D
Q
E
V
L
T
E
D
H
G
G
L
S
Site 24
Y463
L
P
R
N
P
F
D
Y
L
N
G
E
Y
R
A
Site 25
S474
E
Y
R
A
K
K
L
S
R
F
A
R
N
K
V
Site 26
S482
R
F
A
R
N
K
V
S
K
D
P
S
S
Y
V
Site 27
S486
N
K
V
S
K
D
P
S
S
Y
V
K
L
S
V
Site 28
S487
K
V
S
K
D
P
S
S
Y
V
K
L
S
V
G
Site 29
Y488
V
S
K
D
P
S
S
Y
V
K
L
S
V
G
K
Site 30
S492
P
S
S
Y
V
K
L
S
V
G
K
K
T
H
T
Site 31
T499
S
V
G
K
K
T
H
T
S
K
T
C
P
H
N
Site 32
T502
K
K
T
H
T
S
K
T
C
P
H
N
K
D
P
Site 33
S567
Q
R
F
Q
L
D
H
S
G
L
D
S
L
I
S
Site 34
S591
V
E
E
R
E
L
G
S
P
Y
T
G
P
E
A
Site 35
Y593
E
R
E
L
G
S
P
Y
T
G
P
E
A
L
K
Site 36
T594
R
E
L
G
S
P
Y
T
G
P
E
A
L
K
K
Site 37
T625
Q
P
Q
E
E
G
P
T
D
L
P
C
P
P
D
Site 38
S635
P
C
P
P
D
P
A
S
D
T
K
D
V
S
R
Site 39
T637
P
P
D
P
A
S
D
T
K
D
V
S
R
S
T
Site 40
S643
D
T
K
D
V
S
R
S
T
T
T
T
T
S
A
Site 41
T644
T
K
D
V
S
R
S
T
T
T
T
T
S
A
T
Site 42
T645
K
D
V
S
R
S
T
T
T
T
T
S
A
T
T
Site 43
T647
V
S
R
S
T
T
T
T
T
S
A
T
T
V
A
Site 44
S659
T
V
A
T
E
P
T
S
Q
E
T
G
P
E
P
Site 45
S671
P
E
P
K
G
K
D
S
A
K
R
F
C
E
P
Site 46
S684
E
P
I
G
E
K
K
S
P
A
T
I
F
L
T
Site 47
S697
L
T
V
P
G
P
H
S
P
G
P
I
K
S
P
Site 48
S703
H
S
P
G
P
I
K
S
P
R
P
M
K
C
P
Site 49
S712
R
P
M
K
C
P
A
S
P
F
A
W
P
P
K
Site 50
S724
P
P
K
R
L
A
P
S
M
S
S
L
N
S
L
Site 51
S726
K
R
L
A
P
S
M
S
S
L
N
S
L
A
S
Site 52
S727
R
L
A
P
S
M
S
S
L
N
S
L
A
S
S
Site 53
S730
P
S
M
S
S
L
N
S
L
A
S
S
C
F
D
Site 54
T782
I
N
G
C
R
N
L
T
P
C
T
S
S
G
A
Site 55
S786
R
N
L
T
P
C
T
S
S
G
A
D
P
Y
V
Site 56
Y792
T
S
S
G
A
D
P
Y
V
R
V
Y
L
L
P
Site 57
Y796
A
D
P
Y
V
R
V
Y
L
L
P
E
R
K
W
Site 58
T809
K
W
A
C
R
K
K
T
S
V
K
R
K
T
L
Site 59
S810
W
A
C
R
K
K
T
S
V
K
R
K
T
L
E
Site 60
T815
K
T
S
V
K
R
K
T
L
E
P
L
F
D
E
Site 61
S850
K
N
S
R
P
L
G
S
H
R
R
K
E
L
G
Site 62
S864
G
K
V
L
I
D
L
S
K
E
D
L
I
K
G
Site 63
S873
E
D
L
I
K
G
F
S
Q
W
Y
E
L
T
P
Site 64
T879
F
S
Q
W
Y
E
L
T
P
N
G
Q
P
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation