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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM72
Full Name:
Transmembrane protein 72
Alias:
Kidney-specific secretory protein of 37 kDa
Type:
Mass (Da):
29891
Number AA:
275
UniProt ID:
A0PK05
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S75
C
F
Q
C
Q
P
G
S
L
A
D
R
V
R
E
Site 2
S131
G
L
A
Y
F
L
L
S
K
R
K
K
R
K
A
Site 3
S145
A
A
P
E
V
L
A
S
P
E
Q
Y
T
D
P
Site 4
Y149
V
L
A
S
P
E
Q
Y
T
D
P
S
S
S
A
Site 5
T150
L
A
S
P
E
Q
Y
T
D
P
S
S
S
A
V
Site 6
S153
P
E
Q
Y
T
D
P
S
S
S
A
V
S
T
T
Site 7
S154
E
Q
Y
T
D
P
S
S
S
A
V
S
T
T
G
Site 8
S155
Q
Y
T
D
P
S
S
S
A
V
S
T
T
G
S
Site 9
S158
D
P
S
S
S
A
V
S
T
T
G
S
G
D
T
Site 10
T159
P
S
S
S
A
V
S
T
T
G
S
G
D
T
E
Site 11
S162
S
A
V
S
T
T
G
S
G
D
T
E
Q
T
Y
Site 12
Y169
S
G
D
T
E
Q
T
Y
T
F
H
G
A
L
K
Site 13
T170
G
D
T
E
Q
T
Y
T
F
H
G
A
L
K
E
Site 14
S180
G
A
L
K
E
G
P
S
S
L
F
I
H
M
K
Site 15
S181
A
L
K
E
G
P
S
S
L
F
I
H
M
K
S
Site 16
S188
S
L
F
I
H
M
K
S
I
L
K
G
T
K
K
Site 17
T204
S
A
L
Q
P
P
N
T
L
M
E
L
S
L
E
Site 18
S209
P
N
T
L
M
E
L
S
L
E
P
A
D
S
L
Site 19
S215
L
S
L
E
P
A
D
S
L
A
K
K
K
Q
V
Site 20
S244
E
G
L
D
D
G
D
S
E
P
E
E
T
T
S
Site 21
T249
G
D
S
E
P
E
E
T
T
S
D
T
T
P
I
Site 22
S251
S
E
P
E
E
T
T
S
D
T
T
P
I
I
P
Site 23
T253
P
E
E
T
T
S
D
T
T
P
I
I
P
P
P
Site 24
T254
E
E
T
T
S
D
T
T
P
I
I
P
P
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation