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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC24
Full Name:
Tetratricopeptide repeat protein 24
Alias:
Type:
Mass (Da):
63396
Number AA:
582
UniProt ID:
A2A3L6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
S
P
N
P
E
D
V
Site 2
S3
_
_
_
_
_
M
S
S
P
N
P
E
D
V
P
Site 3
S18
R
R
P
E
P
E
P
S
S
S
N
K
K
K
K
Site 4
S19
R
P
E
P
E
P
S
S
S
N
K
K
K
K
K
Site 5
S20
P
E
P
E
P
S
S
S
N
K
K
K
K
K
R
Site 6
S35
K
W
L
R
Q
E
A
S
I
Q
A
L
T
R
A
Site 7
S67
Q
R
A
F
L
L
A
S
K
A
P
Q
T
R
D
Site 8
T75
K
A
P
Q
T
R
D
T
P
V
L
Q
A
C
A
Site 9
Y140
L
P
Q
A
L
A
W
Y
H
R
A
L
G
H
Y
Site 10
Y147
Y
H
R
A
L
G
H
Y
Q
P
Q
G
D
Q
G
Site 11
S181
A
H
C
L
Q
E
A
S
Q
A
Y
A
Q
E
R
Site 12
S207
A
A
G
C
M
L
K
S
G
R
H
R
V
G
E
Site 13
S222
V
V
Q
V
L
E
K
S
R
R
L
A
E
R
S
Site 14
S229
S
R
R
L
A
E
R
S
T
E
R
R
L
L
G
Site 15
T230
R
R
L
A
E
R
S
T
E
R
R
L
L
G
H
Site 16
Y239
R
R
L
L
G
H
L
Y
N
D
L
G
L
G
Y
Site 17
Y289
A
H
N
A
L
G
N
Y
Q
E
A
R
E
F
H
Site 18
S305
K
A
A
D
L
H
G
S
V
G
Q
R
W
E
Q
Site 19
S315
Q
R
W
E
Q
G
R
S
F
G
S
L
A
F
A
Site 20
S318
E
Q
G
R
S
F
G
S
L
A
F
A
L
S
Q
Site 21
Y336
H
K
A
A
R
D
N
Y
L
H
A
L
Q
A
A
Site 22
S346
A
L
Q
A
A
R
D
S
G
D
M
K
G
Q
W
Site 23
Y369
A
A
A
R
L
G
Q
Y
D
Q
A
L
K
Y
Y
Site 24
Y375
Q
Y
D
Q
A
L
K
Y
Y
K
E
A
L
A
Q
Site 25
Y376
Y
D
Q
A
L
K
Y
Y
K
E
A
L
A
Q
C
Site 26
S389
Q
C
Q
K
E
P
D
S
V
R
E
R
L
V
A
Site 27
T416
V
G
L
V
Q
T
H
T
L
T
S
A
P
G
R
Site 28
T418
L
V
Q
T
H
T
L
T
S
A
P
G
R
L
Q
Site 29
S419
V
Q
T
H
T
L
T
S
A
P
G
R
L
Q
A
Site 30
T436
G
A
S
Q
A
E
G
T
P
A
K
A
G
S
S
Site 31
S451
T
A
G
V
Q
H
R
S
S
S
G
W
E
D
E
Site 32
S452
A
G
V
Q
H
R
S
S
S
G
W
E
D
E
E
Site 33
S453
G
V
Q
H
R
S
S
S
G
W
E
D
E
E
F
Site 34
T492
E
L
C
F
L
P
G
T
V
N
H
S
H
H
L
Site 35
S501
N
H
S
H
H
L
A
S
S
C
P
T
F
T
K
Site 36
S502
H
S
H
H
L
A
S
S
C
P
T
F
T
K
H
Site 37
T505
H
L
A
S
S
C
P
T
F
T
K
H
T
P
C
Site 38
T510
C
P
T
F
T
K
H
T
P
C
R
G
T
V
L
Site 39
T515
K
H
T
P
C
R
G
T
V
L
G
K
A
S
I
Site 40
S521
G
T
V
L
G
K
A
S
I
Y
S
P
G
P
R
Site 41
S524
L
G
K
A
S
I
Y
S
P
G
P
R
A
H
L
Site 42
Y543
P
G
P
P
R
A
E
Y
P
S
I
L
V
P
N
Site 43
S545
P
P
R
A
E
Y
P
S
I
L
V
P
N
G
P
Site 44
S557
N
G
P
Q
A
N
R
S
S
R
W
P
R
E
S
Site 45
S558
G
P
Q
A
N
R
S
S
R
W
P
R
E
S
L
Site 46
S564
S
S
R
W
P
R
E
S
L
S
R
S
R
Q
R
Site 47
S566
R
W
P
R
E
S
L
S
R
S
R
Q
R
R
P
Site 48
S568
P
R
E
S
L
S
R
S
R
Q
R
R
P
M
E
Site 49
S576
R
Q
R
R
P
M
E
S
G
I
C
T
I
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation