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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC78
Full Name:
Coiled-coil domain-containing protein 78
Alias:
Type:
Mass (Da):
48521
Number AA:
438
UniProt ID:
A2IDD5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
E
H
A
A
T
T
G
P
R
P
G
P
Site 2
S15
G
P
R
P
G
P
P
S
R
R
V
E
N
V
V
Site 3
S88
A
E
I
F
Q
L
K
S
E
I
L
R
L
E
S
Site 4
S108
E
L
R
G
D
G
T
S
Q
G
C
A
V
P
V
Site 5
S117
G
C
A
V
P
V
E
S
D
P
R
H
P
R
A
Site 6
S139
K
A
Q
V
P
G
H
S
D
D
H
R
F
Q
V
Site 7
S163
N
E
Q
H
R
L
G
S
G
L
Q
G
E
V
K
Site 8
Y243
L
K
K
L
K
D
E
Y
V
L
R
L
Q
H
C
Site 9
S287
D
I
R
A
A
H
R
S
R
E
Q
Q
L
A
R
Site 10
Y299
L
A
R
A
A
R
S
Y
H
K
R
L
V
D
L
Site 11
S307
H
K
R
L
V
D
L
S
R
R
H
E
E
L
L
Site 12
Y317
H
E
E
L
L
V
A
Y
R
A
P
G
N
P
Q
Site 13
S346
V
P
L
V
T
D
F
S
H
R
E
D
Q
H
G
Site 14
S360
G
G
P
G
A
L
L
S
S
P
K
K
R
P
G
Site 15
S361
G
P
G
A
L
L
S
S
P
K
K
R
P
G
G
Site 16
S370
K
K
R
P
G
G
A
S
Q
G
G
T
S
E
P
Site 17
T374
G
G
A
S
Q
G
G
T
S
E
P
Q
G
L
D
Site 18
S375
G
A
S
Q
G
G
T
S
E
P
Q
G
L
D
A
Site 19
S384
P
Q
G
L
D
A
A
S
W
A
Q
I
H
Q
K
Site 20
S396
H
Q
K
L
R
D
F
S
R
S
T
Q
S
W
N
Site 21
S398
K
L
R
D
F
S
R
S
T
Q
S
W
N
G
S
Site 22
T399
L
R
D
F
S
R
S
T
Q
S
W
N
G
S
G
Site 23
S401
D
F
S
R
S
T
Q
S
W
N
G
S
G
H
S
Site 24
S411
G
S
G
H
S
C
W
S
G
P
R
W
L
K
S
Site 25
S418
S
G
P
R
W
L
K
S
N
F
L
S
Y
R
S
Site 26
S422
W
L
K
S
N
F
L
S
Y
R
S
T
W
T
S
Site 27
T426
N
F
L
S
Y
R
S
T
W
T
S
T
W
A
G
Site 28
S429
S
Y
R
S
T
W
T
S
T
W
A
G
T
S
T
Site 29
T430
Y
R
S
T
W
T
S
T
W
A
G
T
S
T
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation