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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR27
Full Name:
WD repeat-containing protein 27
Alias:
Type:
Mass (Da):
90065
Number AA:
827
UniProt ID:
A2RRH5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
N
P
Q
D
I
F
S
S
N
G
G
C
L
S
Site 2
S16
S
S
N
G
G
C
L
S
D
I
V
I
E
K
Y
Site 3
Y23
S
D
I
V
I
E
K
Y
L
V
E
S
K
E
S
Site 4
S27
I
E
K
Y
L
V
E
S
K
E
S
V
S
H
V
Site 5
S30
Y
L
V
E
S
K
E
S
V
S
H
V
Q
L
A
Site 6
T75
R
G
H
H
Q
P
I
T
A
M
A
F
G
N
K
Site 7
T179
F
C
P
W
R
A
G
T
L
I
S
A
S
E
D
Site 8
S182
W
R
A
G
T
L
I
S
A
S
E
D
R
G
F
Site 9
S184
A
G
T
L
I
S
A
S
E
D
R
G
F
K
V
Site 10
T196
F
K
V
W
D
H
C
T
G
S
L
I
Y
S
S
Site 11
Y243
S
L
M
D
G
H
H
Y
R
R
V
A
R
V
D
Site 12
T255
R
V
D
L
R
K
K
T
E
T
F
S
T
R
R
Site 13
T257
D
L
R
K
K
T
E
T
F
S
T
R
R
V
K
Site 14
S259
R
K
K
T
E
T
F
S
T
R
R
V
K
S
G
Site 15
T260
K
K
T
E
T
F
S
T
R
R
V
K
S
G
L
Site 16
S265
F
S
T
R
R
V
K
S
G
L
C
S
Q
P
E
Site 17
S269
R
V
K
S
G
L
C
S
Q
P
E
E
S
Q
L
Site 18
S274
L
C
S
Q
P
E
E
S
Q
L
P
S
T
S
A
Site 19
S278
P
E
E
S
Q
L
P
S
T
S
A
L
G
K
G
Site 20
S314
N
S
A
C
G
C
L
S
S
E
N
T
R
C
V
Site 21
Y344
L
E
V
E
A
A
L
Y
Y
K
D
F
Q
S
L
Site 22
T365
S
C
A
L
R
N
R
T
A
D
Q
K
V
L
C
Site 23
S376
K
V
L
C
L
L
A
S
L
F
G
G
K
I
A
Site 24
S400
V
R
A
Q
Q
C
P
S
M
G
Q
S
L
S
V
Site 25
S404
Q
C
P
S
M
G
Q
S
L
S
V
P
A
S
S
Site 26
S428
L
G
I
A
K
E
K
S
T
K
A
A
S
E
Q
Site 27
S433
E
K
S
T
K
A
A
S
E
Q
R
R
A
A
R
Site 28
S452
D
Q
R
L
V
F
H
S
K
V
R
S
S
G
Y
Site 29
S456
V
F
H
S
K
V
R
S
S
G
Y
A
S
A
P
Site 30
S457
F
H
S
K
V
R
S
S
G
Y
A
S
A
P
H
Site 31
S461
V
R
S
S
G
Y
A
S
A
P
H
V
T
M
F
Site 32
S469
A
P
H
V
T
M
F
S
P
K
T
N
I
K
S
Site 33
T472
V
T
M
F
S
P
K
T
N
I
K
S
E
G
K
Site 34
S476
S
P
K
T
N
I
K
S
E
G
K
G
S
S
R
Site 35
S481
I
K
S
E
G
K
G
S
S
R
S
R
S
S
C
Site 36
S482
K
S
E
G
K
G
S
S
R
S
R
S
S
C
A
Site 37
S484
E
G
K
G
S
S
R
S
R
S
S
C
A
R
E
Site 38
S486
K
G
S
S
R
S
R
S
S
C
A
R
E
A
Y
Site 39
S487
G
S
S
R
S
R
S
S
C
A
R
E
A
Y
P
Site 40
Y493
S
S
C
A
R
E
A
Y
P
V
E
C
A
V
P
Site 41
S552
T
G
T
P
A
V
F
S
G
H
D
G
A
V
N
Site 42
S572
Q
D
R
R
W
L
L
S
A
A
R
D
G
T
L
Site 43
T578
L
S
A
A
R
D
G
T
L
R
M
W
S
A
R
Site 44
S583
D
G
T
L
R
M
W
S
A
R
G
A
E
L
A
Site 45
S599
L
L
G
K
D
M
F
S
K
P
I
Q
S
A
Q
Site 46
Y627
P
E
F
Q
L
L
R
Y
H
I
D
T
C
K
D
Site 47
T631
L
L
R
Y
H
I
D
T
C
K
D
E
I
K
R
Site 48
Y639
C
K
D
E
I
K
R
Y
K
Q
K
S
K
S
K
Site 49
S643
I
K
R
Y
K
Q
K
S
K
S
K
L
I
C
R
Site 50
S645
R
Y
K
Q
K
S
K
S
K
L
I
C
R
L
S
Site 51
T681
L
A
A
G
R
N
R
T
V
E
V
F
D
L
N
Site 52
S714
I
C
Q
N
K
G
S
S
F
T
T
Q
Q
P
Q
Site 53
T717
N
K
G
S
S
F
T
T
Q
Q
P
Q
A
Y
N
Site 54
Y757
E
G
H
P
T
R
G
Y
P
C
G
I
A
F
S
Site 55
Y780
G
A
E
D
R
H
A
Y
V
Y
E
M
G
S
S
Site 56
Y782
E
D
R
H
A
Y
V
Y
E
M
G
S
S
T
F
Site 57
S786
A
Y
V
Y
E
M
G
S
S
T
F
S
H
R
L
Site 58
T788
V
Y
E
M
G
S
S
T
F
S
H
R
L
A
G
Site 59
S790
E
M
G
S
S
T
F
S
H
R
L
A
G
H
T
Site 60
T797
S
H
R
L
A
G
H
T
D
T
V
T
G
V
A
Site 61
T801
A
G
H
T
D
T
V
T
G
V
A
F
N
P
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation