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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0564
Full Name:
Uncharacterized protein KIAA0564
Alias:
Type:
Unknown function
Mass (Da):
210920
Number AA:
UniProt ID:
A3KMH1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
G
G
H
G
G
P
A
S
R
R
M
R
L
L
L
Site 2
S50
V
R
L
L
H
A
G
S
G
A
D
T
G
D
T
Site 3
T54
H
A
G
S
G
A
D
T
G
D
T
V
N
I
G
Site 4
T57
S
G
A
D
T
G
D
T
V
N
I
G
D
V
S
Site 5
S64
T
V
N
I
G
D
V
S
Y
K
L
K
I
P
K
Site 6
Y65
V
N
I
G
D
V
S
Y
K
L
K
I
P
K
N
Site 7
Y80
P
E
L
V
P
Q
N
Y
I
S
D
S
L
A
Q
Site 8
S84
P
Q
N
Y
I
S
D
S
L
A
Q
S
V
V
Q
Site 9
S88
I
S
D
S
L
A
Q
S
V
V
Q
H
L
R
W
Site 10
S118
P
P
G
P
L
R
R
S
I
A
M
Q
Y
L
E
Site 11
T127
A
M
Q
Y
L
E
L
T
K
R
E
V
E
Y
I
Site 12
S137
E
V
E
Y
I
A
L
S
R
D
T
T
E
T
D
Site 13
T140
Y
I
A
L
S
R
D
T
T
E
T
D
L
K
Q
Site 14
T141
I
A
L
S
R
D
T
T
E
T
D
L
K
Q
R
Site 15
T155
R
R
E
I
R
A
G
T
A
F
Y
I
D
Q
C
Site 16
S208
E
D
G
R
F
L
M
S
A
E
R
Y
D
K
L
Site 17
Y212
F
L
M
S
A
E
R
Y
D
K
L
L
R
D
H
Site 18
T220
D
K
L
L
R
D
H
T
K
K
E
L
D
S
W
Site 19
Y248
L
G
L
P
V
P
R
Y
S
G
N
P
L
D
P
Site 20
S249
G
L
P
V
P
R
Y
S
G
N
P
L
D
P
P
Site 21
Y267
R
F
Q
A
R
D
I
Y
Y
L
P
F
K
D
Q
Site 22
Y268
F
Q
A
R
D
I
Y
Y
L
P
F
K
D
Q
L
Site 23
S286
Y
S
I
G
A
N
V
S
A
E
K
V
S
Q
L
Site 24
T298
S
Q
L
L
S
F
A
T
T
L
C
S
Q
E
S
Site 25
T299
Q
L
L
S
F
A
T
T
L
C
S
Q
E
S
S
Site 26
S302
S
F
A
T
T
L
C
S
Q
E
S
S
T
L
G
Site 27
S305
T
T
L
C
S
Q
E
S
S
T
L
G
L
P
D
Site 28
S306
T
L
C
S
Q
E
S
S
T
L
G
L
P
D
F
Site 29
S367
K
R
F
E
L
Q
D
S
G
S
S
L
L
P
K
Site 30
S369
F
E
L
Q
D
S
G
S
S
L
L
P
K
E
I
Site 31
S388
K
M
M
E
N
H
V
S
Q
A
S
V
T
I
R
Site 32
S391
E
N
H
V
S
Q
A
S
V
T
I
R
I
A
D
Site 33
S413
P
A
G
T
R
L
L
S
Q
P
C
A
S
D
R
Site 34
T424
A
S
D
R
F
I
Q
T
L
S
H
K
Q
L
Q
Site 35
S426
D
R
F
I
Q
T
L
S
H
K
Q
L
Q
A
E
Site 36
T454
G
G
K
G
C
G
K
T
V
I
A
K
N
F
A
Site 37
Y474
N
I
E
P
I
M
L
Y
Q
D
M
T
A
R
D
Site 38
T478
I
M
L
Y
Q
D
M
T
A
R
D
L
L
Q
Q
Site 39
Y487
R
D
L
L
Q
Q
R
Y
T
L
P
N
G
D
T
Site 40
T488
D
L
L
Q
Q
R
Y
T
L
P
N
G
D
T
A
Site 41
T494
Y
T
L
P
N
G
D
T
A
W
R
S
S
P
L
Site 42
S498
N
G
D
T
A
W
R
S
S
P
L
V
N
A
A
Site 43
S499
G
D
T
A
W
R
S
S
P
L
V
N
A
A
L
Site 44
S537
L
I
H
D
R
E
L
S
L
Y
D
G
S
R
L
Site 45
Y539
H
D
R
E
L
S
L
Y
D
G
S
R
L
L
R
Site 46
Y550
R
L
L
R
E
D
R
Y
M
R
L
K
E
E
L
Site 47
S560
L
K
E
E
L
Q
L
S
D
E
Q
L
Q
K
R
Site 48
S589
A
E
P
P
V
I
G
S
T
A
H
Q
W
L
G
Site 49
S614
Y
M
K
P
L
V
K
S
E
E
I
Q
V
I
K
Site 50
S637
E
A
L
D
K
L
L
S
F
T
H
K
L
R
E
Site 51
T645
F
T
H
K
L
R
E
T
Q
D
P
T
A
Q
S
Site 52
S652
T
Q
D
P
T
A
Q
S
L
A
A
S
L
S
T
Site 53
S666
T
R
Q
L
L
R
I
S
R
R
L
S
Q
Y
P
Site 54
S670
L
R
I
S
R
R
L
S
Q
Y
P
N
E
N
L
Site 55
Y672
I
S
R
R
L
S
Q
Y
P
N
E
N
L
H
S
Site 56
S679
Y
P
N
E
N
L
H
S
A
V
T
K
A
C
L
Site 57
Y722
L
E
P
E
L
K
D
Y
K
C
E
V
T
S
G
Site 58
Y741
G
A
V
S
A
P
I
Y
N
A
H
E
K
M
K
Site 59
Y804
L
L
N
R
P
R
E
Y
I
Q
L
H
R
D
T
Site 60
T811
Y
I
Q
L
H
R
D
T
T
V
Q
T
L
T
L
Site 61
T812
I
Q
L
H
R
D
T
T
V
Q
T
L
T
L
Q
Site 62
T815
H
R
D
T
T
V
Q
T
L
T
L
Q
P
S
V
Site 63
T817
D
T
T
V
Q
T
L
T
L
Q
P
S
V
K
D
Site 64
S881
G
R
R
I
V
A
N
S
A
N
V
N
G
R
E
Site 65
S935
V
D
N
P
K
P
H
S
E
L
E
M
L
R
Q
Site 66
Y943
E
L
E
M
L
R
Q
Y
G
P
N
V
P
E
P
Site 67
Y973
A
D
Q
G
I
I
N
Y
P
Y
S
T
R
E
V
Site 68
Y975
Q
G
I
I
N
Y
P
Y
S
T
R
E
V
V
N
Site 69
T992
K
H
L
Q
K
F
P
T
E
G
L
S
S
V
V
Site 70
Y1008
N
V
F
D
F
D
S
Y
N
N
D
M
R
E
I
Site 71
S1033
P
I
G
A
K
P
T
S
V
Q
L
A
K
E
L
Site 72
Y1050
P
E
Q
T
F
M
G
Y
W
T
I
G
Q
A
R
Site 73
Y1085
A
L
I
N
I
Q
E
Y
P
I
E
R
H
E
E
Site 74
S1094
I
E
R
H
E
E
R
S
L
N
F
T
E
E
C
Site 75
T1098
E
E
R
S
L
N
F
T
E
E
C
A
S
W
R
Site 76
Y1129
E
N
E
Q
N
T
L
Y
V
V
T
C
N
P
A
Site 77
Y1139
T
C
N
P
A
S
L
Y
F
M
N
M
T
G
K
Site 78
S1209
L
H
R
L
I
L
P
S
E
K
F
T
S
K
K
Site 79
T1213
I
L
P
S
E
K
F
T
S
K
K
P
F
W
W
Site 80
Y1228
N
K
E
E
A
E
T
Y
K
M
C
K
E
F
S
Site 81
S1235
Y
K
M
C
K
E
F
S
H
K
N
W
L
V
F
Site 82
Y1243
H
K
N
W
L
V
F
Y
K
E
K
G
N
S
L
Site 83
S1249
F
Y
K
E
K
G
N
S
L
T
V
L
D
V
L
Site 84
T1251
K
E
K
G
N
S
L
T
V
L
D
V
L
E
G
Site 85
S1264
E
G
R
T
H
T
I
S
L
P
I
N
L
K
T
Site 86
T1287
W
L
L
V
E
S
K
T
N
Q
K
Y
L
L
T
Site 87
Y1291
E
S
K
T
N
Q
K
Y
L
L
T
K
P
A
H
Site 88
S1301
T
K
P
A
H
I
E
S
E
G
S
G
V
C
Q
Site 89
Y1310
G
S
G
V
C
Q
L
Y
V
L
K
E
E
P
P
Site 90
S1318
V
L
K
E
E
P
P
S
T
G
F
G
V
T
Q
Site 91
T1319
L
K
E
E
P
P
S
T
G
F
G
V
T
Q
E
Site 92
T1327
G
F
G
V
T
Q
E
T
E
F
S
I
P
H
K
Site 93
S1330
V
T
Q
E
T
E
F
S
I
P
H
K
I
S
S
Site 94
S1336
F
S
I
P
H
K
I
S
S
D
Q
L
S
S
E
Site 95
S1337
S
I
P
H
K
I
S
S
D
Q
L
S
S
E
H
Site 96
S1341
K
I
S
S
D
Q
L
S
S
E
H
L
S
S
A
Site 97
S1342
I
S
S
D
Q
L
S
S
E
H
L
S
S
A
V
Site 98
S1346
Q
L
S
S
E
H
L
S
S
A
V
E
Q
K
I
Site 99
S1347
L
S
S
E
H
L
S
S
A
V
E
Q
K
I
A
Site 100
S1355
A
V
E
Q
K
I
A
S
P
N
R
I
L
S
D
Site 101
S1361
A
S
P
N
R
I
L
S
D
E
K
N
Y
A
T
Site 102
T1368
S
D
E
K
N
Y
A
T
I
V
V
G
F
P
D
Site 103
S1378
V
G
F
P
D
L
M
S
P
S
E
V
Y
S
W
Site 104
S1380
F
P
D
L
M
S
P
S
E
V
Y
S
W
K
R
Site 105
S1384
M
S
P
S
E
V
Y
S
W
K
R
P
S
S
L
Site 106
S1389
V
Y
S
W
K
R
P
S
S
L
H
K
R
S
G
Site 107
S1390
Y
S
W
K
R
P
S
S
L
H
K
R
S
G
T
Site 108
S1395
P
S
S
L
H
K
R
S
G
T
D
T
S
F
Y
Site 109
T1397
S
L
H
K
R
S
G
T
D
T
S
F
Y
R
G
Site 110
T1399
H
K
R
S
G
T
D
T
S
F
Y
R
G
K
K
Site 111
S1400
K
R
S
G
T
D
T
S
F
Y
R
G
K
K
K
Site 112
Y1402
S
G
T
D
T
S
F
Y
R
G
K
K
K
R
G
Site 113
T1410
R
G
K
K
K
R
G
T
P
K
Q
S
N
C
V
Site 114
S1414
K
R
G
T
P
K
Q
S
N
C
V
T
L
L
D
Site 115
T1418
P
K
Q
S
N
C
V
T
L
L
D
T
N
Q
V
Site 116
Y1440
E
V
P
L
K
D
I
Y
P
K
D
V
T
P
P
Site 117
T1445
D
I
Y
P
K
D
V
T
P
P
Q
T
S
G
Y
Site 118
Y1452
T
P
P
Q
T
S
G
Y
I
E
V
T
D
L
Q
Site 119
S1471
R
Y
I
P
I
P
R
S
E
S
L
S
P
Y
T
Site 120
S1473
I
P
I
P
R
S
E
S
L
S
P
Y
T
T
W
Site 121
S1475
I
P
R
S
E
S
L
S
P
Y
T
T
W
L
S
Site 122
Y1477
R
S
E
S
L
S
P
Y
T
T
W
L
S
T
I
Site 123
T1478
S
E
S
L
S
P
Y
T
T
W
L
S
T
I
S
Site 124
T1479
E
S
L
S
P
Y
T
T
W
L
S
T
I
S
D
Site 125
S1482
S
P
Y
T
T
W
L
S
T
I
S
D
T
D
A
Site 126
T1539
D
D
R
N
M
Q
I
T
I
N
R
D
S
G
E
Site 127
S1544
Q
I
T
I
N
R
D
S
G
E
D
V
S
S
P
Site 128
S1549
R
D
S
G
E
D
V
S
S
P
K
H
G
K
E
Site 129
S1550
D
S
G
E
D
V
S
S
P
K
H
G
K
E
D
Site 130
T1578
G
G
T
G
G
R
D
T
A
G
L
G
G
K
G
Site 131
Y1588
L
G
G
K
G
G
P
Y
R
L
D
A
G
H
T
Site 132
T1595
Y
R
L
D
A
G
H
T
V
Y
Q
V
S
Q
A
Site 133
Y1597
L
D
A
G
H
T
V
Y
Q
V
S
Q
A
E
K
Site 134
S1600
G
H
T
V
Y
Q
V
S
Q
A
E
K
D
A
V
Site 135
S1633
R
L
K
E
I
Q
M
S
E
Y
D
A
A
T
Y
Site 136
Y1635
K
E
I
Q
M
S
E
Y
D
A
A
T
Y
E
R
Site 137
T1639
M
S
E
Y
D
A
A
T
Y
E
R
F
S
G
A
Site 138
Y1640
S
E
Y
D
A
A
T
Y
E
R
F
S
G
A
V
Site 139
S1644
A
A
T
Y
E
R
F
S
G
A
V
R
R
Q
V
Site 140
S1653
A
V
R
R
Q
V
H
S
L
R
I
I
L
D
N
Site 141
T1689
A
K
I
I
D
G
L
T
G
E
K
A
I
Y
K
Site 142
Y1695
L
T
G
E
K
A
I
Y
K
R
R
G
E
L
E
Site 143
S1707
E
L
E
P
Q
L
G
S
P
Q
Q
K
P
K
R
Site 144
Y1726
V
D
V
S
G
S
M
Y
R
F
N
R
M
D
G
Site 145
Y1752
V
M
E
A
F
E
N
Y
E
E
K
F
Q
Y
D
Site 146
Y1758
N
Y
E
E
K
F
Q
Y
D
I
V
G
H
S
G
Site 147
T1791
Q
R
L
E
I
L
K
T
M
H
A
H
S
Q
F
Site 148
S1801
A
H
S
Q
F
C
M
S
G
D
H
T
L
E
G
Site 149
T1805
F
C
M
S
G
D
H
T
L
E
G
T
E
H
A
Site 150
T1869
G
S
L
G
D
Q
A
T
R
L
Q
R
T
L
P
Site 151
S1880
R
T
L
P
A
G
R
S
F
V
A
M
D
T
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation