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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAMB4
Full Name:
Laminin subunit beta-4
Alias:
Laminin beta-1-related protein
Type:
Mass (Da):
193540
Number AA:
1761
UniProt ID:
A4D0S4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
F
L
H
L
G
W
L
S
Y
S
K
A
Q
D
D
Site 2
T32
R
G
A
C
H
P
T
T
G
D
L
L
V
G
R
Site 3
T41
D
L
L
V
G
R
N
T
Q
L
M
A
S
S
T
Site 4
S47
N
T
Q
L
M
A
S
S
T
C
G
L
S
R
A
Site 5
T48
T
Q
L
M
A
S
S
T
C
G
L
S
R
A
Q
Site 6
S52
A
S
S
T
C
G
L
S
R
A
Q
K
Y
C
I
Site 7
Y57
G
L
S
R
A
Q
K
Y
C
I
L
S
Y
L
E
Site 8
S61
A
Q
K
Y
C
I
L
S
Y
L
E
G
E
Q
K
Site 9
Y62
Q
K
Y
C
I
L
S
Y
L
E
G
E
Q
K
C
Site 10
Y78
I
C
D
S
R
F
P
Y
D
P
Y
D
Q
P
N
Site 11
Y81
S
R
F
P
Y
D
P
Y
D
Q
P
N
S
H
T
Site 12
S95
T
I
E
N
V
I
V
S
F
E
P
D
R
E
K
Site 13
S115
E
N
G
L
D
H
V
S
I
R
L
D
L
E
A
Site 14
Y149
L
V
E
R
S
T
D
Y
G
H
N
W
K
V
F
Site 15
T165
Y
F
A
K
D
C
A
T
S
F
P
N
I
T
S
Site 16
S166
F
A
K
D
C
A
T
S
F
P
N
I
T
S
G
Site 17
S172
T
S
F
P
N
I
T
S
G
Q
A
Q
G
V
G
Site 18
S185
V
G
D
I
V
C
D
S
K
Y
S
D
I
E
P
Site 19
Y187
D
I
V
C
D
S
K
Y
S
D
I
E
P
S
T
Site 20
S188
I
V
C
D
S
K
Y
S
D
I
E
P
S
T
G
Site 21
S206
V
L
K
V
L
D
P
S
F
E
I
E
N
P
Y
Site 22
S214
F
E
I
E
N
P
Y
S
P
Y
I
Q
D
L
V
Site 23
S248
L
G
R
R
Q
N
D
S
L
D
K
Y
Y
Y
A
Site 24
Y252
Q
N
D
S
L
D
K
Y
Y
Y
A
L
Y
E
M
Site 25
Y253
N
D
S
L
D
K
Y
Y
Y
A
L
Y
E
M
I
Site 26
Y254
D
S
L
D
K
Y
Y
Y
A
L
Y
E
M
I
V
Site 27
Y257
D
K
Y
Y
Y
A
L
Y
E
M
I
V
R
G
S
Site 28
S286
K
M
R
G
D
V
F
S
P
P
G
M
V
H
G
Site 29
S333
D
N
A
C
R
S
C
S
C
N
S
H
S
S
R
Site 30
S336
C
R
S
C
S
C
N
S
H
S
S
R
C
H
F
Site 31
S338
S
C
S
C
N
S
H
S
S
R
C
H
F
D
M
Site 32
S339
C
S
C
N
S
H
S
S
R
C
H
F
D
M
T
Site 33
T347
R
C
H
F
D
M
T
T
Y
L
A
S
G
G
L
Site 34
Y379
D
R
C
R
P
L
F
Y
R
D
P
L
K
T
I
Site 35
T385
F
Y
R
D
P
L
K
T
I
S
D
P
Y
A
C
Site 36
S387
R
D
P
L
K
T
I
S
D
P
Y
A
C
I
P
Site 37
S445
K
P
N
H
Y
G
L
S
A
T
D
P
L
G
C
Site 38
Y493
C
E
E
C
T
V
G
Y
W
G
L
G
N
H
L
Site 39
Y514
D
C
D
I
G
G
A
Y
S
N
V
C
S
P
K
Site 40
S519
G
A
Y
S
N
V
C
S
P
K
N
G
Q
C
E
Site 41
S537
H
V
T
G
R
S
C
S
E
P
A
P
G
Y
F
Site 42
Y553
A
P
L
N
F
Y
L
Y
E
A
E
E
A
T
T
Site 43
T560
Y
E
A
E
E
A
T
T
L
Q
G
L
A
P
L
Site 44
S569
Q
G
L
A
P
L
G
S
E
T
F
G
Q
S
P
Site 45
T592
P
V
P
G
N
P
V
T
W
T
G
P
G
F
A
Site 46
T594
P
G
N
P
V
T
W
T
G
P
G
F
A
R
V
Site 47
Y626
D
F
T
I
A
I
H
Y
E
T
Q
S
A
A
D
Site 48
T653
S
E
H
C
I
P
K
T
L
Q
S
K
P
Q
S
Site 49
S656
C
I
P
K
T
L
Q
S
K
P
Q
S
F
A
L
Site 50
S660
T
L
Q
S
K
P
Q
S
F
A
L
P
A
A
T
Site 51
Y689
V
Q
Y
S
I
D
V
Y
F
S
Q
P
L
Q
G
Site 52
S691
Y
S
I
D
V
Y
F
S
Q
P
L
Q
G
E
S
Site 53
S698
S
Q
P
L
Q
G
E
S
H
A
H
S
H
V
L
Site 54
S702
Q
G
E
S
H
A
H
S
H
V
L
V
D
S
L
Site 55
S717
G
L
I
P
Q
I
N
S
L
E
N
F
C
S
K
Site 56
S723
N
S
L
E
N
F
C
S
K
Q
D
L
D
E
Y
Site 57
Y730
S
K
Q
D
L
D
E
Y
Q
L
H
N
C
V
E
Site 58
S759
E
R
L
I
I
S
M
S
A
K
L
H
D
G
A
Site 59
S776
C
K
C
H
P
Q
G
S
V
G
S
S
C
S
R
Site 60
S779
H
P
Q
G
S
V
G
S
S
C
S
R
L
G
G
Site 61
S780
P
Q
G
S
V
G
S
S
C
S
R
L
G
G
Q
Site 62
S782
G
S
V
G
S
S
C
S
R
L
G
G
Q
C
Q
Site 63
S803
G
R
C
C
D
R
C
S
T
G
S
Y
D
L
G
Site 64
Y807
D
R
C
S
T
G
S
Y
D
L
G
H
H
G
C
Site 65
T827
H
P
Q
G
S
K
D
T
V
C
D
Q
V
T
G
Site 66
T876
A
E
L
C
D
P
E
T
G
S
C
F
N
C
G
Site 67
Y898
C
E
R
C
I
D
G
Y
Y
G
N
P
S
S
G
Site 68
Y899
E
R
C
I
D
G
Y
Y
G
N
P
S
S
G
Q
Site 69
S904
G
Y
Y
G
N
P
S
S
G
Q
P
C
R
P
C
Site 70
S919
L
C
P
D
D
P
S
S
N
Q
Y
F
A
H
S
Site 71
Y922
D
D
P
S
S
N
Q
Y
F
A
H
S
C
Y
Q
Site 72
Y957
G
E
C
S
T
G
F
Y
G
N
P
R
I
S
G
Site 73
T979
C
N
N
N
I
D
V
T
D
P
E
S
C
S
R
Site 74
S983
I
D
V
T
D
P
E
S
C
S
R
V
T
G
E
Site 75
S985
V
T
D
P
E
S
C
S
R
V
T
G
E
C
L
Site 76
T988
P
E
S
C
S
R
V
T
G
E
C
L
R
C
L
Site 77
S1023
N
Q
T
C
R
R
C
S
C
H
A
S
G
V
S
Site 78
S1027
R
R
C
S
C
H
A
S
G
V
S
P
M
E
C
Site 79
S1030
S
C
H
A
S
G
V
S
P
M
E
C
P
P
G
Site 80
Y1068
C
D
R
C
A
D
G
Y
W
N
L
V
P
G
R
Site 81
T1086
S
C
D
C
D
P
R
T
S
Q
S
S
H
C
D
Site 82
S1090
D
P
R
T
S
Q
S
S
H
C
D
Q
L
T
G
Site 83
T1096
S
S
H
C
D
Q
L
T
G
Q
C
P
C
K
L
Site 84
Y1117
C
S
E
C
Q
E
N
Y
Y
G
D
P
P
G
R
Site 85
Y1118
S
E
C
Q
E
N
Y
Y
G
D
P
P
G
R
C
Site 86
S1154
C
R
C
R
E
G
V
S
G
Q
R
C
D
R
C
Site 87
S1166
D
R
C
A
R
G
H
S
Q
E
F
P
T
C
L
Site 88
T1185
C
F
D
Q
W
D
H
T
I
S
S
L
S
K
A
Site 89
S1188
Q
W
D
H
T
I
S
S
L
S
K
A
V
Q
G
Site 90
S1190
D
H
T
I
S
S
L
S
K
A
V
Q
G
L
M
Site 91
T1209
N
M
E
D
K
R
E
T
L
P
V
C
E
A
D
Site 92
Y1247
K
F
L
K
V
K
D
Y
H
D
S
V
R
R
Q
Site 93
T1274
E
F
Q
D
L
K
D
T
I
E
R
A
K
N
E
Site 94
S1303
Q
S
S
V
L
N
A
S
I
A
D
S
S
E
N
Site 95
S1307
L
N
A
S
I
A
D
S
S
E
N
I
K
K
Y
Site 96
S1308
N
A
S
I
A
D
S
S
E
N
I
K
K
Y
Y
Site 97
Y1314
S
S
E
N
I
K
K
Y
Y
H
I
S
S
S
A
Site 98
Y1315
S
E
N
I
K
K
Y
Y
H
I
S
S
S
A
E
Site 99
S1318
I
K
K
Y
Y
H
I
S
S
S
A
E
K
K
I
Site 100
S1319
K
K
Y
Y
H
I
S
S
S
A
E
K
K
I
N
Site 101
S1320
K
Y
Y
H
I
S
S
S
A
E
K
K
I
N
E
Site 102
S1329
E
K
K
I
N
E
T
S
S
T
I
N
T
S
A
Site 103
S1330
K
K
I
N
E
T
S
S
T
I
N
T
S
A
N
Site 104
T1331
K
I
N
E
T
S
S
T
I
N
T
S
A
N
T
Site 105
T1334
E
T
S
S
T
I
N
T
S
A
N
T
R
N
D
Site 106
T1344
N
T
R
N
D
L
L
T
I
L
D
T
L
T
S
Site 107
S1351
T
I
L
D
T
L
T
S
K
G
N
L
S
L
E
Site 108
S1356
L
T
S
K
G
N
L
S
L
E
R
L
K
Q
I
Site 109
T1395
P
C
G
G
A
L
C
T
G
R
K
G
H
R
K
Site 110
S1411
R
G
P
G
C
H
G
S
L
T
L
S
T
N
A
Site 111
T1413
P
G
C
H
G
S
L
T
L
S
T
N
A
L
Q
Site 112
S1415
C
H
G
S
L
T
L
S
T
N
A
L
Q
K
A
Site 113
S1427
Q
K
A
Q
E
A
K
S
I
I
R
N
L
D
K
Site 114
S1447
K
N
Q
I
E
S
I
S
E
Q
A
E
V
S
K
Site 115
S1471
L
G
N
I
R
N
Q
S
D
S
E
E
E
N
I
Site 116
S1473
N
I
R
N
Q
S
D
S
E
E
E
N
I
N
L
Site 117
S1515
D
I
H
L
P
I
P
S
Q
N
L
T
D
E
L
Site 118
T1519
P
I
P
S
Q
N
L
T
D
E
L
V
K
I
Q
Site 119
Y1535
H
M
Q
L
C
E
D
Y
R
T
D
E
N
R
L
Site 120
T1537
Q
L
C
E
D
Y
R
T
D
E
N
R
L
N
E
Site 121
T1572
I
L
L
N
L
D
K
T
L
N
Q
L
Q
Q
A
Site 122
S1588
I
T
Q
G
R
A
N
S
T
I
T
Q
L
T
A
Site 123
S1616
N
Q
T
R
E
M
K
S
E
L
E
L
A
K
Q
Site 124
S1625
L
E
L
A
K
Q
R
S
G
L
E
D
G
L
S
Site 125
S1632
S
G
L
E
D
G
L
S
L
L
Q
T
K
L
Q
Site 126
T1636
D
G
L
S
L
L
Q
T
K
L
Q
R
H
Q
D
Site 127
S1661
S
A
Q
H
Q
A
G
S
L
E
K
E
F
V
E
Site 128
T1680
Y
A
I
L
Q
R
K
T
S
T
T
G
L
T
K
Site 129
S1681
A
I
L
Q
R
K
T
S
T
T
G
L
T
K
E
Site 130
T1683
L
Q
R
K
T
S
T
T
G
L
T
K
E
T
L
Site 131
T1715
E
A
K
I
R
R
I
T
D
L
E
R
K
I
Q
Site 132
Y1756
I
V
E
Q
E
K
K
Y
A
R
C
Y
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation