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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PI4KAP2
Full Name:
Putative phosphatidylinositol 4-kinase alpha-like protein P2
Alias:
phosphatidylinositol 4-kinase alpha-like protein P2; PI4P2
Type:
Kinase (non-protein)
Mass (Da):
66981
Number AA:
592
UniProt ID:
A4QPH2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004428
GO:0016773
PhosphoSite+
KinaseNET
Biological Process:
GO:0046854
GO:0048015
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
A
D
P
L
A
A
S
E
A
S
Q
P
K
P
Site 2
Y54
Q
R
F
E
I
A
K
Y
C
S
S
D
Q
V
E
Site 3
S57
E
I
A
K
Y
C
S
S
D
Q
V
E
I
F
S
Site 4
S65
D
Q
V
E
I
F
S
S
L
L
Q
R
S
M
S
Site 5
S70
F
S
S
L
L
Q
R
S
M
S
L
N
I
G
R
Site 6
S72
S
L
L
Q
R
S
M
S
L
N
I
G
R
A
K
Site 7
S81
N
I
G
R
A
K
G
S
M
N
R
H
V
A
A
Site 8
Y122
N
V
L
R
E
K
I
Y
S
T
A
F
D
Y
F
Site 9
S123
V
L
R
E
K
I
Y
S
T
A
F
D
Y
F
S
Site 10
Y128
I
Y
S
T
A
F
D
Y
F
S
C
P
P
K
F
Site 11
S130
S
T
A
F
D
Y
F
S
C
P
P
K
F
P
T
Site 12
Y163
A
M
F
S
D
K
K
Y
L
T
A
S
Q
L
V
Site 13
T165
F
S
D
K
K
Y
L
T
A
S
Q
L
V
P
P
Site 14
S167
D
K
K
Y
L
T
A
S
Q
L
V
P
P
A
D
Site 15
T187
E
Q
L
V
E
E
N
T
G
S
L
S
G
P
A
Site 16
S189
L
V
E
E
N
T
G
S
L
S
G
P
A
K
D
Site 17
S191
E
E
N
T
G
S
L
S
G
P
A
K
D
F
Y
Site 18
Y198
S
G
P
A
K
D
F
Y
Q
R
E
F
D
F
F
Site 19
Y218
V
S
A
I
I
K
P
Y
P
K
G
D
E
R
K
Site 20
S230
E
R
K
K
A
C
L
S
A
L
S
E
V
T
V
Site 21
S242
V
T
V
Q
P
G
C
S
L
P
S
N
P
E
A
Site 22
Y256
A
I
V
L
D
V
D
Y
K
S
G
T
P
M
Q
Site 23
S258
V
L
D
V
D
Y
K
S
G
T
P
M
Q
S
A
Site 24
T260
D
V
D
Y
K
S
G
T
P
M
Q
S
A
A
K
Site 25
S264
K
S
G
T
P
M
Q
S
A
A
K
A
P
Y
L
Site 26
Y270
Q
S
A
A
K
A
P
Y
L
A
K
F
K
V
K
Site 27
S293
K
E
G
L
R
C
R
S
D
S
E
D
E
C
S
Site 28
S295
G
L
R
C
R
S
D
S
E
D
E
C
S
T
Q
Site 29
S300
S
D
S
E
D
E
C
S
T
Q
E
A
D
G
Q
Site 30
S310
E
A
D
G
Q
K
I
S
W
Q
A
A
I
F
K
Site 31
T332
K
S
Y
W
G
A
R
T
P
T
D
R
I
L
R
Site 32
T334
Y
W
G
A
R
T
P
T
D
R
I
L
R
L
P
Site 33
T390
I
E
C
I
P
D
C
T
S
R
D
Q
L
G
R
Site 34
S391
E
C
I
P
D
C
T
S
R
D
Q
L
G
R
Q
Site 35
T399
R
D
Q
L
G
R
Q
T
D
F
G
M
Y
D
Y
Site 36
Y404
R
Q
T
D
F
G
M
Y
D
Y
F
T
R
Q
Y
Site 37
Y406
T
D
F
G
M
Y
D
Y
F
T
R
Q
Y
G
D
Site 38
Y411
Y
D
Y
F
T
R
Q
Y
G
D
E
S
T
L
A
Site 39
T416
R
Q
Y
G
D
E
S
T
L
A
F
Q
Q
A
C
Site 40
S469
D
F
G
F
M
F
E
S
S
P
G
G
N
L
G
Site 41
S470
F
G
F
M
F
E
S
S
P
G
G
N
L
G
W
Site 42
T543
L
P
C
F
R
G
Q
T
I
K
F
L
K
H
R
Site 43
S552
K
F
L
K
H
R
F
S
P
N
M
T
E
R
E
Site 44
T556
H
R
F
S
P
N
M
T
E
R
E
A
A
N
F
Site 45
S574
V
I
Q
S
C
F
L
S
N
R
S
R
T
Y
N
Site 46
T579
F
L
S
N
R
S
R
T
Y
N
M
I
Q
Y
Y
Site 47
Y580
L
S
N
R
S
R
T
Y
N
M
I
Q
Y
Y
Q
Site 48
Y585
R
T
Y
N
M
I
Q
Y
Y
Q
N
D
I
P
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation