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Updated November 2019
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Protein Info
Short Name:
CMYA3
Full Name:
Xin actin-binding repeat-containing protein 2
Alias:
Beta-xin; Cardiomyopathy associated 3; Cardiomyopathy-associated protein 3; Xeplin; Xin actin-binding repeat containing 2; Xin actin-binding repeat-containing 2; Xin repeat 2; XIRP2
Type:
Unknown function
Mass (Da):
382300
Number AA:
3374
UniProt ID:
A4UGR9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
H
S
R
I
F
E
A
T
A
G
P
N
K
P
E
Site 2
S22
A
G
P
N
K
P
E
S
G
F
A
E
D
S
A
Site 3
S28
E
S
G
F
A
E
D
S
A
A
R
G
E
G
V
Site 4
S36
A
A
R
G
E
G
V
S
D
L
H
E
V
V
S
Site 5
S43
S
D
L
H
E
V
V
S
L
K
E
R
M
A
R
Site 6
Y51
L
K
E
R
M
A
R
Y
Q
A
A
V
S
R
G
Site 7
S62
V
S
R
G
D
C
R
S
F
S
A
N
M
M
E
Site 8
S64
R
G
D
C
R
S
F
S
A
N
M
M
E
E
S
Site 9
T92
K
Q
F
E
D
E
I
T
S
S
R
N
T
F
A
Site 10
S93
Q
F
E
D
E
I
T
S
S
R
N
T
F
A
Q
Site 11
S94
F
E
D
E
I
T
S
S
R
N
T
F
A
Q
Y
Site 12
T97
E
I
T
S
S
R
N
T
F
A
Q
Y
Q
Y
Q
Site 13
Y101
S
R
N
T
F
A
Q
Y
Q
Y
Q
H
Q
N
R
Site 14
S116
S
E
Q
E
A
I
H
S
S
Q
V
G
T
S
R
Site 15
S117
E
Q
E
A
I
H
S
S
Q
V
G
T
S
R
S
Site 16
T121
I
H
S
S
Q
V
G
T
S
R
S
S
Q
E
M
Site 17
S125
Q
V
G
T
S
R
S
S
Q
E
M
A
R
N
E
Site 18
T146
Q
K
I
D
V
H
G
T
E
M
V
S
H
L
E
Site 19
Y168
Q
A
S
Q
F
H
Q
Y
V
Q
E
T
V
I
D
Site 20
T172
F
H
Q
Y
V
Q
E
T
V
I
D
T
P
E
D
Site 21
T176
V
Q
E
T
V
I
D
T
P
E
D
E
E
I
P
Site 22
S197
L
K
E
Q
F
E
K
S
A
Q
E
K
I
L
Y
Site 23
Y204
S
A
Q
E
K
I
L
Y
S
D
K
E
M
T
T
Site 24
S205
A
Q
E
K
I
L
Y
S
D
K
E
M
T
T
P
Site 25
T211
Y
S
D
K
E
M
T
T
P
A
K
Q
I
K
T
Site 26
S220
A
K
Q
I
K
T
E
S
E
Y
E
E
T
F
K
Site 27
Y222
Q
I
K
T
E
S
E
Y
E
E
T
F
K
P
S
Site 28
T225
T
E
S
E
Y
E
E
T
F
K
P
S
S
V
V
Site 29
S229
Y
E
E
T
F
K
P
S
S
V
V
S
T
S
S
Site 30
S230
E
E
T
F
K
P
S
S
V
V
S
T
S
S
T
Site 31
T234
K
P
S
S
V
V
S
T
S
S
T
S
C
V
S
Site 32
S235
P
S
S
V
V
S
T
S
S
T
S
C
V
S
T
Site 33
S236
S
S
V
V
S
T
S
S
T
S
C
V
S
T
S
Site 34
T237
S
V
V
S
T
S
S
T
S
C
V
S
T
S
Q
Site 35
S238
V
V
S
T
S
S
T
S
C
V
S
T
S
Q
R
Site 36
T242
S
S
T
S
C
V
S
T
S
Q
R
K
E
T
S
Site 37
S243
S
T
S
C
V
S
T
S
Q
R
K
E
T
S
T
Site 38
T248
S
T
S
Q
R
K
E
T
S
T
T
R
Y
S
D
Site 39
S249
T
S
Q
R
K
E
T
S
T
T
R
Y
S
D
H
Site 40
T250
S
Q
R
K
E
T
S
T
T
R
Y
S
D
H
S
Site 41
T251
Q
R
K
E
T
S
T
T
R
Y
S
D
H
S
V
Site 42
Y253
K
E
T
S
T
T
R
Y
S
D
H
S
V
T
S
Site 43
S254
E
T
S
T
T
R
Y
S
D
H
S
V
T
S
S
Site 44
S257
T
T
R
Y
S
D
H
S
V
T
S
S
T
L
A
Site 45
S261
S
D
H
S
V
T
S
S
T
L
A
Q
I
N
A
Site 46
T274
N
A
T
S
S
G
M
T
E
E
F
P
P
P
P
Site 47
T292
L
Q
T
S
V
D
V
T
A
F
S
Q
S
P
E
Site 48
S295
S
V
D
V
T
A
F
S
Q
S
P
E
L
P
S
Site 49
S297
D
V
T
A
F
S
Q
S
P
E
L
P
S
P
P
Site 50
S302
S
Q
S
P
E
L
P
S
P
P
R
R
L
P
V
Site 51
Y314
L
P
V
P
K
D
V
Y
S
K
Q
R
N
L
Y
Site 52
S315
P
V
P
K
D
V
Y
S
K
Q
R
N
L
Y
E
Site 53
Y321
Y
S
K
Q
R
N
L
Y
E
L
N
R
L
Y
K
Site 54
Y327
L
Y
E
L
N
R
L
Y
K
H
I
H
P
E
L
Site 55
Y342
R
K
N
L
E
K
D
Y
I
S
E
V
S
E
I
Site 56
S344
N
L
E
K
D
Y
I
S
E
V
S
E
I
V
S
Site 57
S347
K
D
Y
I
S
E
V
S
E
I
V
S
S
Q
M
Site 58
S351
S
E
V
S
E
I
V
S
S
Q
M
N
S
G
S
Site 59
S352
E
V
S
E
I
V
S
S
Q
M
N
S
G
S
S
Site 60
S356
I
V
S
S
Q
M
N
S
G
S
S
V
S
A
D
Site 61
S358
S
S
Q
M
N
S
G
S
S
V
S
A
D
V
Q
Site 62
S359
S
Q
M
N
S
G
S
S
V
S
A
D
V
Q
Q
Site 63
Y369
A
D
V
Q
Q
A
R
Y
V
F
E
N
T
N
D
Site 64
S377
V
F
E
N
T
N
D
S
S
Q
K
D
L
N
S
Site 65
S378
F
E
N
T
N
D
S
S
Q
K
D
L
N
S
E
Site 66
S384
S
S
Q
K
D
L
N
S
E
R
E
Y
L
E
W
Site 67
Y388
D
L
N
S
E
R
E
Y
L
E
W
D
E
I
L
Site 68
S413
F
E
N
Q
P
L
D
S
I
N
N
G
S
P
D
Site 69
S418
L
D
S
I
N
N
G
S
P
D
E
G
D
I
S
Site 70
S425
S
P
D
E
G
D
I
S
R
G
I
A
D
Q
E
Site 71
Y441
I
A
G
G
D
V
K
Y
T
T
W
M
F
E
T
Site 72
T453
F
E
T
Q
P
I
D
T
L
G
A
Y
S
S
D
Site 73
Y457
P
I
D
T
L
G
A
Y
S
S
D
T
V
E
N
Site 74
S459
D
T
L
G
A
Y
S
S
D
T
V
E
N
A
E
Site 75
T461
L
G
A
Y
S
S
D
T
V
E
N
A
E
K
I
Site 76
S497
S
M
N
K
M
H
Q
S
Q
E
E
S
A
V
T
Site 77
S501
M
H
Q
S
Q
E
E
S
A
V
T
I
S
K
D
Site 78
T504
S
Q
E
E
S
A
V
T
I
S
K
D
I
T
G
Site 79
S506
E
E
S
A
V
T
I
S
K
D
I
T
G
G
D
Site 80
T516
I
T
G
G
D
V
K
T
V
R
Y
M
F
E
T
Site 81
Y519
G
D
V
K
T
V
R
Y
M
F
E
T
Q
H
L
Site 82
T523
T
V
R
Y
M
F
E
T
Q
H
L
D
Q
L
G
Site 83
S534
D
Q
L
G
Q
L
H
S
V
D
E
V
H
L
L
Site 84
S545
V
H
L
L
Q
L
R
S
E
L
K
E
I
K
G
Site 85
Y567
C
F
E
T
Q
P
L
Y
V
I
R
D
G
S
G
Site 86
S573
L
Y
V
I
R
D
G
S
G
Q
M
L
E
I
K
Site 87
T581
G
Q
M
L
E
I
K
T
V
H
R
E
D
V
E
Site 88
T594
V
E
K
G
D
V
R
T
A
R
W
M
F
E
T
Site 89
T612
D
T
I
N
K
D
I
T
E
I
K
V
V
R
G
Site 90
S621
I
K
V
V
R
G
I
S
M
E
E
N
V
K
G
Site 91
S686
K
E
V
P
D
A
D
S
L
Q
R
E
E
I
I
Site 92
S715
P
I
E
A
L
K
D
S
P
D
I
G
K
L
Q
Site 93
S727
K
L
Q
K
I
T
A
S
E
E
E
K
G
D
V
Site 94
T759
D
K
K
E
Y
T
R
T
V
K
L
E
E
V
D
Site 95
Y773
D
R
G
D
V
K
N
Y
T
H
I
F
E
S
N
Site 96
T774
R
G
D
V
K
N
Y
T
H
I
F
E
S
N
N
Site 97
T810
L
N
K
S
L
F
E
T
T
P
L
Y
A
I
Q
Site 98
T811
N
K
S
L
F
E
T
T
P
L
Y
A
I
Q
D
Site 99
Y823
I
Q
D
P
L
G
K
Y
H
Q
V
K
T
V
Q
Site 100
T828
G
K
Y
H
Q
V
K
T
V
Q
Q
E
E
I
V
Site 101
T886
S
A
K
W
L
F
E
T
Q
P
L
D
S
I
K
Site 102
S891
F
E
T
Q
P
L
D
S
I
K
Y
F
S
D
V
Site 103
Y894
Q
P
L
D
S
I
K
Y
F
S
D
V
E
E
T
Site 104
S896
L
D
S
I
K
Y
F
S
D
V
E
E
T
E
S
Site 105
S903
S
D
V
E
E
T
E
S
K
T
E
Q
T
R
D
Site 106
S930
F
E
T
Q
P
M
E
S
L
Y
E
K
V
S
L
Site 107
Y932
T
Q
P
M
E
S
L
Y
E
K
V
S
L
M
T
Site 108
S936
E
S
L
Y
E
K
V
S
L
M
T
S
S
E
E
Site 109
S940
E
K
V
S
L
M
T
S
S
E
E
I
H
K
G
Site 110
T963
F
E
T
Q
P
L
D
T
I
K
D
D
S
E
T
Site 111
S968
L
D
T
I
K
D
D
S
E
T
A
V
K
L
Q
Site 112
T970
T
I
K
D
D
S
E
T
A
V
K
L
Q
T
V
Site 113
T976
E
T
A
V
K
L
Q
T
V
K
Q
E
E
I
Q
Site 114
S1001
F
E
T
E
N
L
D
S
I
Q
G
E
E
V
K
Site 115
S1023
D
I
Q
A
G
D
V
S
S
M
R
Y
K
F
E
Site 116
S1024
I
Q
A
G
D
V
S
S
M
R
Y
K
F
E
N
Site 117
Y1027
G
D
V
S
S
M
R
Y
K
F
E
N
Q
S
L
Site 118
S1033
R
Y
K
F
E
N
Q
S
L
D
S
I
S
S
S
Site 119
S1036
F
E
N
Q
S
L
D
S
I
S
S
S
S
E
E
Site 120
S1038
N
Q
S
L
D
S
I
S
S
S
S
E
E
V
L
Site 121
S1039
Q
S
L
D
S
I
S
S
S
S
E
E
V
L
K
Site 122
S1040
S
L
D
S
I
S
S
S
S
E
E
V
L
K
K
Site 123
S1041
L
D
S
I
S
S
S
S
E
E
V
L
K
K
I
Site 124
T1050
E
V
L
K
K
I
K
T
L
K
T
E
D
I
Q
Site 125
T1053
K
K
I
K
T
L
K
T
E
D
I
Q
K
G
N
Site 126
S1079
P
I
D
K
I
K
E
S
Q
E
G
D
E
C
V
Site 127
T1088
E
G
D
E
C
V
K
T
V
T
D
I
Q
G
G
Site 128
S1108
C
F
I
F
E
T
F
S
L
D
E
I
K
E
E
Site 129
S1116
L
D
E
I
K
E
E
S
D
Y
I
S
T
K
K
Site 130
Y1118
E
I
K
E
E
S
D
Y
I
S
T
K
K
T
I
Site 131
S1120
K
E
E
S
D
Y
I
S
T
K
K
T
I
T
E
Site 132
T1124
D
Y
I
S
T
K
K
T
I
T
E
E
V
I
Q
Site 133
S1136
V
I
Q
G
D
V
K
S
Y
R
M
L
F
E
T
Site 134
Y1137
I
Q
G
D
V
K
S
Y
R
M
L
F
E
T
Q
Site 135
T1143
S
Y
R
M
L
F
E
T
Q
P
L
Y
A
I
Q
Site 136
Y1147
L
F
E
T
Q
P
L
Y
A
I
Q
D
R
E
G
Site 137
S1155
A
I
Q
D
R
E
G
S
Y
H
E
V
T
T
V
Site 138
Y1156
I
Q
D
R
E
G
S
Y
H
E
V
T
T
V
K
Site 139
T1181
G
T
R
W
L
F
E
T
K
P
L
D
S
I
N
Site 140
S1186
F
E
T
K
P
L
D
S
I
N
K
S
E
T
V
Site 141
S1190
P
L
D
S
I
N
K
S
E
T
V
Y
V
I
K
Site 142
T1192
D
S
I
N
K
S
E
T
V
Y
V
I
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R
I
L
G
V
Site 295
S2455
V
C
S
D
N
Q
L
S
T
T
S
P
E
T
V
Site 296
T2456
C
S
D
N
Q
L
S
T
T
S
P
E
T
V
A
Site 297
S2458
D
N
Q
L
S
T
T
S
P
E
T
V
A
A
K
Site 298
T2461
L
S
T
T
S
P
E
T
V
A
A
K
R
L
H
Site 299
S2487
M
K
K
E
V
L
Q
S
S
R
D
I
M
Q
S
Site 300
S2494
S
S
R
D
I
M
Q
S
K
S
A
C
E
I
K
Site 301
S2496
R
D
I
M
Q
S
K
S
A
C
E
I
K
Q
S
Site 302
S2503
S
A
C
E
I
K
Q
S
H
Q
E
C
S
T
Q
Site 303
T2512
Q
E
C
S
T
Q
Q
T
Q
Q
K
K
Y
L
E
Site 304
Y2517
Q
Q
T
Q
Q
K
K
Y
L
E
Q
L
H
L
P
Site 305
S2526
E
Q
L
H
L
P
Q
S
K
P
I
S
P
N
F
Site 306
S2530
L
P
Q
S
K
P
I
S
P
N
F
K
V
K
T
Site 307
T2546
K
L
P
T
L
D
H
T
L
N
E
T
D
H
S
Site 308
T2550
L
D
H
T
L
N
E
T
D
H
S
Y
E
S
H
Site 309
S2553
T
L
N
E
T
D
H
S
Y
E
S
H
K
Q
Q
Site 310
Y2554
L
N
E
T
D
H
S
Y
E
S
H
K
Q
Q
S
Site 311
S2556
E
T
D
H
S
Y
E
S
H
K
Q
Q
S
E
I
Site 312
T2567
Q
S
E
I
D
V
Q
T
F
T
K
K
Q
Y
L
Site 313
T2579
Q
Y
L
K
T
K
K
T
E
A
S
T
E
C
S
Site 314
S2582
K
T
K
K
T
E
A
S
T
E
C
S
H
K
Q
Site 315
S2586
T
E
A
S
T
E
C
S
H
K
Q
S
L
A
E
Site 316
S2590
T
E
C
S
H
K
Q
S
L
A
E
R
H
Y
Q
Site 317
Y2596
Q
S
L
A
E
R
H
Y
Q
L
P
K
K
E
K
Site 318
T2606
P
K
K
E
K
R
V
T
V
Q
L
P
T
E
S
Site 319
S2633
P
R
K
Q
R
E
F
S
G
S
D
R
G
K
L
Site 320
S2635
K
Q
R
E
F
S
G
S
D
R
G
K
L
P
G
Site 321
S2643
D
R
G
K
L
P
G
S
E
E
K
N
Q
G
P
Site 322
T2662
R
K
E
E
R
L
I
T
E
R
K
H
E
H
L
Site 323
S2673
H
E
H
L
K
N
K
S
A
P
K
V
V
K
Q
Site 324
S2689
V
I
D
A
H
L
D
S
Q
T
Q
N
F
Q
Q
Site 325
T2691
D
A
H
L
D
S
Q
T
Q
N
F
Q
Q
T
Q
Site 326
S2717
K
L
P
Q
P
Y
N
S
L
Q
E
E
K
C
L
Site 327
T2746
K
D
S
K
Q
E
I
T
Q
N
K
S
F
F
S
Site 328
S2750
Q
E
I
T
Q
N
K
S
F
F
S
S
V
K
E
Site 329
S2753
T
Q
N
K
S
F
F
S
S
V
K
E
S
Q
R
Site 330
S2754
Q
N
K
S
F
F
S
S
V
K
E
S
Q
R
D
Site 331
S2758
F
F
S
S
V
K
E
S
Q
R
D
D
G
K
G
Site 332
S2784
E
E
L
Q
Q
I
L
S
R
V
K
Q
F
E
A
Site 333
S2796
F
E
A
E
P
N
K
S
G
L
K
T
F
Q
T
Site 334
T2800
P
N
K
S
G
L
K
T
F
Q
T
L
L
N
T
Site 335
S2814
T
I
P
G
W
L
I
S
E
D
K
R
E
Y
A
Site 336
Y2820
I
S
E
D
K
R
E
Y
A
V
H
I
A
M
E
Site 337
T2857
S
Y
E
N
I
I
Q
T
A
M
M
S
S
K
T
Site 338
S2862
I
Q
T
A
M
M
S
S
K
T
G
K
P
G
N
Site 339
T2872
G
K
P
G
N
K
P
T
S
L
D
E
T
S
S
Site 340
S2873
K
P
G
N
K
P
T
S
L
D
E
T
S
S
K
Site 341
T2877
K
P
T
S
L
D
E
T
S
S
K
V
S
N
V
Site 342
S2878
P
T
S
L
D
E
T
S
S
K
V
S
N
V
H
Site 343
S2879
T
S
L
D
E
T
S
S
K
V
S
N
V
H
V
Site 344
S2882
D
E
T
S
S
K
V
S
N
V
H
V
S
N
N
Site 345
S2887
K
V
S
N
V
H
V
S
N
N
K
N
S
E
Q
Site 346
T2904
N
K
I
A
K
E
K
T
V
Q
H
Q
V
A
A
Site 347
T2916
V
A
A
H
H
E
A
T
V
R
S
H
V
K
T
Site 348
T2923
T
V
R
S
H
V
K
T
H
Q
E
I
K
L
D
Site 349
S2932
Q
E
I
K
L
D
D
S
N
I
P
P
P
S
L
Site 350
S2938
D
S
N
I
P
P
P
S
L
K
T
R
P
P
S
Site 351
T2941
I
P
P
P
S
L
K
T
R
P
P
S
P
T
F
Site 352
S2945
S
L
K
T
R
P
P
S
P
T
F
I
T
I
E
Site 353
T2947
K
T
R
P
P
S
P
T
F
I
T
I
E
S
T
Site 354
S2953
P
T
F
I
T
I
E
S
T
A
R
R
T
E
N
Site 355
T2954
T
F
I
T
I
E
S
T
A
R
R
T
E
N
P
Site 356
T2958
I
E
S
T
A
R
R
T
E
N
P
T
K
N
E
Site 357
T2962
A
R
R
T
E
N
P
T
K
N
E
L
S
Q
S
Site 358
S2967
N
P
T
K
N
E
L
S
Q
S
P
K
K
D
S
Site 359
S2969
T
K
N
E
L
S
Q
S
P
K
K
D
S
Y
V
Site 360
S2974
S
Q
S
P
K
K
D
S
Y
V
E
P
P
P
R
Site 361
Y2975
Q
S
P
K
K
D
S
Y
V
E
P
P
P
R
R
Site 362
S2985
P
P
P
R
R
P
M
S
Q
K
S
E
I
H
R
Site 363
S2988
R
R
P
M
S
Q
K
S
E
I
H
R
A
N
T
Site 364
T2995
S
E
I
H
R
A
N
T
S
P
S
P
P
R
S
Site 365
S2996
E
I
H
R
A
N
T
S
P
S
P
P
R
S
R
Site 366
S2998
H
R
A
N
T
S
P
S
P
P
R
S
R
S
E
Site 367
S3002
T
S
P
S
P
P
R
S
R
S
E
Q
L
V
R
Site 368
S3004
P
S
P
P
R
S
R
S
E
Q
L
V
R
L
K
Site 369
T3013
Q
L
V
R
L
K
D
T
T
A
K
L
S
K
G
Site 370
T3014
L
V
R
L
K
D
T
T
A
K
L
S
K
G
A
Site 371
S3042
K
R
S
E
I
I
M
S
P
A
T
L
R
R
Q
Site 372
S3059
I
E
T
R
G
R
D
S
P
P
T
I
T
I
P
Site 373
T3062
R
G
R
D
S
P
P
T
I
T
I
P
V
N
I
Site 374
S3076
I
N
H
A
A
S
G
S
F
R
E
S
V
D
A
Site 375
S3080
A
S
G
S
F
R
E
S
V
D
A
Q
E
E
I
Site 376
T3095
R
K
V
E
K
R
A
T
Y
V
H
K
D
G
L
Site 377
Y3096
K
V
E
K
R
A
T
Y
V
H
K
D
G
L
N
Site 378
T3112
T
D
H
M
V
P
D
T
E
S
Y
D
A
V
E
Site 379
S3114
H
M
V
P
D
T
E
S
Y
D
A
V
E
I
I
Site 380
Y3115
M
V
P
D
T
E
S
Y
D
A
V
E
I
I
R
Site 381
S3131
V
A
V
P
P
R
L
S
E
H
T
Q
R
Y
E
Site 382
T3134
P
P
R
L
S
E
H
T
Q
R
Y
E
A
A
N
Site 383
S3171
E
F
E
H
G
P
V
S
E
A
K
S
N
R
R
Site 384
S3175
G
P
V
S
E
A
K
S
N
R
R
V
Y
A
K
Site 385
Y3180
A
K
S
N
R
R
V
Y
A
K
G
E
T
N
H
Site 386
T3195
N
I
Q
Q
E
S
R
T
F
C
K
E
E
F
G
Site 387
T3204
C
K
E
E
F
G
L
T
S
L
G
N
T
S
F
Site 388
S3205
K
E
E
F
G
L
T
S
L
G
N
T
S
F
T
Site 389
S3210
L
T
S
L
G
N
T
S
F
T
D
F
S
C
K
Site 390
T3212
S
L
G
N
T
S
F
T
D
F
S
C
K
H
P
Site 391
S3215
N
T
S
F
T
D
F
S
C
K
H
P
R
E
L
Site 392
S3235
V
K
Q
P
R
I
C
S
E
T
R
S
L
S
E
Site 393
T3237
Q
P
R
I
C
S
E
T
R
S
L
S
E
H
F
Site 394
S3239
R
I
C
S
E
T
R
S
L
S
E
H
F
S
G
Site 395
S3241
C
S
E
T
R
S
L
S
E
H
F
S
G
M
D
Site 396
S3245
R
S
L
S
E
H
F
S
G
M
D
A
F
E
S
Site 397
S3252
S
G
M
D
A
F
E
S
Q
I
V
E
S
K
M
Site 398
S3257
F
E
S
Q
I
V
E
S
K
M
K
T
S
S
S
Site 399
T3261
I
V
E
S
K
M
K
T
S
S
S
H
S
S
E
Site 400
S3262
V
E
S
K
M
K
T
S
S
S
H
S
S
E
A
Site 401
S3263
E
S
K
M
K
T
S
S
S
H
S
S
E
A
G
Site 402
S3264
S
K
M
K
T
S
S
S
H
S
S
E
A
G
K
Site 403
S3266
M
K
T
S
S
S
H
S
S
E
A
G
K
S
G
Site 404
S3267
K
T
S
S
S
H
S
S
E
A
G
K
S
G
C
Site 405
S3272
H
S
S
E
A
G
K
S
G
C
D
F
K
H
A
Site 406
T3282
D
F
K
H
A
P
P
T
Y
E
D
V
I
A
G
Site 407
Y3283
F
K
H
A
P
P
T
Y
E
D
V
I
A
G
H
Site 408
S3295
A
G
H
I
L
D
I
S
D
S
P
K
E
V
R
Site 409
S3297
H
I
L
D
I
S
D
S
P
K
E
V
R
K
N
Site 410
T3308
V
R
K
N
F
Q
K
T
W
Q
E
S
G
R
V
Site 411
T3334
S
A
T
E
M
R
T
T
F
Q
E
E
S
A
F
Site 412
S3339
R
T
T
F
Q
E
E
S
A
F
I
S
E
A
A
Site 413
S3343
Q
E
E
S
A
F
I
S
E
A
A
A
P
R
Q
Site 414
Y3354
A
P
R
Q
G
N
M
Y
T
L
S
K
D
S
L
Site 415
T3355
P
R
Q
G
N
M
Y
T
L
S
K
D
S
L
S
Site 416
S3357
Q
G
N
M
Y
T
L
S
K
D
S
L
S
N
G
Site 417
S3360
M
Y
T
L
S
K
D
S
L
S
N
G
V
P
S
Site 418
S3362
T
L
S
K
D
S
L
S
N
G
V
P
S
G
R
Site 419
S3367
S
L
S
N
G
V
P
S
G
R
Q
A
E
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation