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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POTEF
Full Name:
POTE ankyrin domain family member F
Alias:
A26C1B; ANKRD26-like family C member 1B; Chimeric POTE-actin protein
Type:
Mass (Da):
121445
Number AA:
1075
UniProt ID:
A5A3E0
International Prot ID:
IPI00739539
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
V
V
E
V
D
S
M
P
A
A
S
S
V
Site 2
S12
V
D
S
M
P
A
A
S
S
V
K
K
P
F
G
Site 3
S13
D
S
M
P
A
A
S
S
V
K
K
P
F
G
L
Site 4
S41
C
C
R
E
S
G
K
S
N
V
G
T
S
G
D
Site 5
T45
S
G
K
S
N
V
G
T
S
G
D
H
D
D
S
Site 6
S52
T
S
G
D
H
D
D
S
A
M
K
T
L
R
S
Site 7
T56
H
D
D
S
A
M
K
T
L
R
S
K
M
G
K
Site 8
S78
C
C
R
G
S
G
K
S
N
V
G
A
S
G
D
Site 9
S89
A
S
G
D
H
D
D
S
A
M
K
T
L
R
N
Site 10
T93
H
D
D
S
A
M
K
T
L
R
N
K
M
G
K
Site 11
S112
C
F
P
C
C
R
G
S
S
K
S
K
V
G
A
Site 12
S113
F
P
C
C
R
G
S
S
K
S
K
V
G
A
W
Site 13
S115
C
C
R
G
S
S
K
S
K
V
G
A
W
G
D
Site 14
Y123
K
V
G
A
W
G
D
Y
D
D
S
A
F
M
E
Site 15
Y133
S
A
F
M
E
P
R
Y
H
V
R
G
E
D
L
Site 16
T164
L
I
V
M
L
R
D
T
D
V
N
K
Q
D
K
Site 17
T175
K
Q
D
K
Q
K
R
T
A
L
H
L
A
S
A
Site 18
Y238
D
P
N
I
P
D
E
Y
G
N
T
T
L
H
Y
Site 19
Y245
Y
G
N
T
T
L
H
Y
A
I
Y
N
E
D
K
Site 20
Y248
T
T
L
H
Y
A
I
Y
N
E
D
K
L
M
A
Site 21
S267
L
Y
G
A
D
I
E
S
K
N
K
H
G
L
T
Site 22
T274
S
K
N
K
H
G
L
T
P
L
L
L
G
V
H
Site 23
S332
L
E
Q
N
I
D
V
S
S
Q
D
L
S
G
Q
Site 24
S333
E
Q
N
I
D
V
S
S
Q
D
L
S
G
Q
T
Site 25
S337
D
V
S
S
Q
D
L
S
G
Q
T
A
R
E
Y
Site 26
Y344
S
G
Q
T
A
R
E
Y
A
V
S
S
H
H
H
Site 27
Y360
I
C
Q
L
L
S
D
Y
K
E
K
Q
M
L
K
Site 28
S373
L
K
I
S
S
E
N
S
N
P
E
Q
D
L
K
Site 29
S383
E
Q
D
L
K
L
T
S
E
E
E
S
Q
R
F
Site 30
S387
K
L
T
S
E
E
E
S
Q
R
F
K
G
S
E
Site 31
S396
R
F
K
G
S
E
N
S
Q
P
E
K
M
S
Q
Site 32
S402
N
S
Q
P
E
K
M
S
Q
E
P
E
I
N
K
Site 33
S452
G
L
I
P
Q
R
K
S
R
T
P
E
N
Q
Q
Site 34
T454
I
P
Q
R
K
S
R
T
P
E
N
Q
Q
F
P
Site 35
Y468
P
D
N
E
S
E
E
Y
H
R
I
C
E
L
L
Site 36
Y478
I
C
E
L
L
S
D
Y
K
E
K
Q
M
P
K
Site 37
Y486
K
E
K
Q
M
P
K
Y
S
S
E
N
S
N
P
Site 38
S487
E
K
Q
M
P
K
Y
S
S
E
N
S
N
P
E
Site 39
S488
K
Q
M
P
K
Y
S
S
E
N
S
N
P
E
Q
Site 40
S491
P
K
Y
S
S
E
N
S
N
P
E
Q
D
L
K
Site 41
S501
E
Q
D
L
K
L
T
S
E
E
E
S
Q
R
L
Site 42
S505
K
L
T
S
E
E
E
S
Q
R
L
K
G
S
E
Site 43
S511
E
S
Q
R
L
K
G
S
E
N
G
Q
P
E
K
Site 44
S520
N
G
Q
P
E
K
R
S
Q
E
P
E
I
N
K
Site 45
T548
E
M
K
K
H
R
S
T
H
V
G
F
P
E
N
Site 46
S575
G
L
I
P
P
R
K
S
R
T
P
E
S
Q
Q
Site 47
T577
I
P
P
R
K
S
R
T
P
E
S
Q
Q
F
P
Site 48
S580
R
K
S
R
T
P
E
S
Q
Q
F
P
D
T
E
Site 49
T586
E
S
Q
Q
F
P
D
T
E
N
E
E
Y
H
S
Site 50
Y591
P
D
T
E
N
E
E
Y
H
S
D
E
Q
N
D
Site 51
S593
T
E
N
E
E
Y
H
S
D
E
Q
N
D
T
Q
Site 52
T599
H
S
D
E
Q
N
D
T
Q
K
Q
F
C
E
E
Site 53
S632
E
V
V
E
K
M
N
S
E
L
S
L
S
C
K
Site 54
S635
E
K
M
N
S
E
L
S
L
S
C
K
K
E
K
Site 55
S637
M
N
S
E
L
S
L
S
C
K
K
E
K
D
I
Site 56
S649
K
D
I
L
H
E
N
S
T
L
R
E
E
I
A
Site 57
T650
D
I
L
H
E
N
S
T
L
R
E
E
I
A
M
Site 58
T664
M
L
R
L
E
L
D
T
M
K
H
Q
S
Q
L
Site 59
S669
L
D
T
M
K
H
Q
S
Q
L
R
E
K
K
Y
Site 60
Y676
S
Q
L
R
E
K
K
Y
L
E
D
I
E
S
V
Site 61
S682
K
Y
L
E
D
I
E
S
V
K
K
R
N
D
N
Site 62
T705
E
L
T
M
D
D
D
T
A
V
L
V
I
D
N
Site 63
S733
A
P
R
A
V
F
P
S
I
V
G
R
P
R
Q
Site 64
S752
G
G
M
H
Q
K
E
S
Y
V
G
K
E
A
Q
Site 65
Y753
G
M
H
Q
K
E
S
Y
V
G
K
E
A
Q
S
Site 66
S760
Y
V
G
K
E
A
Q
S
K
R
G
I
L
T
L
Site 67
T766
Q
S
K
R
G
I
L
T
L
K
Y
P
M
E
H
Site 68
Y769
R
G
I
L
T
L
K
Y
P
M
E
H
G
I
I
Site 69
T789
M
E
K
I
W
H
H
T
F
Y
N
E
L
R
V
Site 70
Y791
K
I
W
H
H
T
F
Y
N
E
L
R
V
A
P
Site 71
T809
P
V
L
L
T
E
A
T
L
N
P
K
A
N
R
Site 72
T849
L
Y
T
S
G
R
T
T
G
I
V
M
D
S
G
Site 73
S855
T
T
G
I
V
M
D
S
G
D
G
V
T
H
T
Site 74
T862
S
G
D
G
V
T
H
T
V
P
I
Y
E
G
N
Site 75
Y866
V
T
H
T
V
P
I
Y
E
G
N
A
L
P
H
Site 76
T875
G
N
A
L
P
H
A
T
L
R
L
D
L
A
G
Site 77
Y888
A
G
R
E
L
P
D
Y
L
M
K
I
L
T
E
Site 78
T894
D
Y
L
M
K
I
L
T
E
H
G
Y
R
F
T
Site 79
T901
T
E
H
G
Y
R
F
T
T
M
A
E
R
E
I
Site 80
T902
E
H
G
Y
R
F
T
T
M
A
E
R
E
I
V
Site 81
Y918
D
I
K
E
K
L
C
Y
V
A
L
D
F
E
Q
Site 82
T929
D
F
E
Q
E
M
A
T
V
A
S
S
S
S
L
Site 83
S935
A
T
V
A
S
S
S
S
L
E
K
S
Y
E
L
Site 84
S939
S
S
S
S
L
E
K
S
Y
E
L
P
D
G
Q
Site 85
Y940
S
S
S
L
E
K
S
Y
E
L
P
D
G
Q
V
Site 86
T949
L
P
D
G
Q
V
I
T
I
G
N
E
R
F
R
Site 87
T978
S
C
G
I
H
E
T
T
F
N
S
I
M
K
S
Site 88
S985
T
F
N
S
I
M
K
S
D
V
D
I
R
K
D
Site 89
Y994
V
D
I
R
K
D
L
Y
T
N
T
V
L
S
G
Site 90
T995
D
I
R
K
D
L
Y
T
N
T
V
L
S
G
G
Site 91
T997
R
K
D
L
Y
T
N
T
V
L
S
G
G
T
T
Site 92
Y1006
L
S
G
G
T
T
M
Y
P
G
M
A
H
R
M
Site 93
Y1037
I
A
P
P
K
R
K
Y
S
V
W
V
G
G
S
Site 94
S1038
A
P
P
K
R
K
Y
S
V
W
V
G
G
S
I
Site 95
Y1062
M
W
I
S
K
Q
E
Y
D
E
S
G
P
S
I
Site 96
S1065
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Site 97
S1068
E
Y
D
E
S
G
P
S
I
V
H
R
K
C
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation