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Updated November 2019
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Protein Info
Short Name:
KRBA1
Full Name:
Protein KRBA1
Alias:
Type:
Mass (Da):
107512
Number AA:
1030
UniProt ID:
A5PL33
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
R
E
N
Y
E
T
L
V
S
V
G
T
A
Site 2
S24
L
P
L
S
A
F
L
S
P
S
E
P
G
R
A
Site 3
S36
G
R
A
V
G
G
G
S
H
A
D
E
G
Q
E
Site 4
S58
Q
G
G
Q
P
R
H
S
L
H
L
T
A
L
V
Site 5
S85
E
V
K
G
A
M
D
S
P
E
S
E
S
R
G
Site 6
S88
G
A
M
D
S
P
E
S
E
S
R
G
A
S
L
Site 7
S90
M
D
S
P
E
S
E
S
R
G
A
S
L
D
G
Site 8
S94
E
S
E
S
R
G
A
S
L
D
G
E
R
A
S
Site 9
S101
S
L
D
G
E
R
A
S
P
E
A
A
A
A
R
Site 10
T125
S
C
L
P
D
G
P
T
S
Q
P
H
L
A
T
Site 11
S126
C
L
P
D
G
P
T
S
Q
P
H
L
A
T
T
Site 12
T133
S
Q
P
H
L
A
T
T
P
T
D
S
S
C
S
Site 13
T135
P
H
L
A
T
T
P
T
D
S
S
C
S
S
G
Site 14
S137
L
A
T
T
P
T
D
S
S
C
S
S
G
P
T
Site 15
S138
A
T
T
P
T
D
S
S
C
S
S
G
P
T
G
Site 16
S140
T
P
T
D
S
S
C
S
S
G
P
T
G
D
G
Site 17
S141
P
T
D
S
S
C
S
S
G
P
T
G
D
G
V
Site 18
T144
S
S
C
S
S
G
P
T
G
D
G
V
Q
G
S
Site 19
S151
T
G
D
G
V
Q
G
S
P
L
P
I
K
T
A
Site 20
T157
G
S
P
L
P
I
K
T
A
D
K
P
W
P
T
Site 21
S177
G
A
L
G
G
E
P
S
P
P
T
H
S
P
S
Site 22
T180
G
G
E
P
S
P
P
T
H
S
P
S
R
R
K
Site 23
S182
E
P
S
P
P
T
H
S
P
S
R
R
K
S
H
Site 24
S184
S
P
P
T
H
S
P
S
R
R
K
S
H
R
G
Site 25
S188
H
S
P
S
R
R
K
S
H
R
G
Q
E
R
G
Site 26
T196
H
R
G
Q
E
R
G
T
S
E
A
G
I
S
P
Site 27
S197
R
G
Q
E
R
G
T
S
E
A
G
I
S
P
G
Site 28
S202
G
T
S
E
A
G
I
S
P
G
N
S
P
L
Q
Site 29
S206
A
G
I
S
P
G
N
S
P
L
Q
G
L
I
N
Site 30
T228
P
G
P
R
H
P
E
T
S
P
S
F
L
P
P
Site 31
S229
G
P
R
H
P
E
T
S
P
S
F
L
P
P
L
Site 32
S231
R
H
P
E
T
S
P
S
F
L
P
P
L
P
S
Site 33
T241
P
P
L
P
S
L
G
T
S
R
L
T
R
A
D
Site 34
S242
P
L
P
S
L
G
T
S
R
L
T
R
A
D
L
Site 35
T245
S
L
G
T
S
R
L
T
R
A
D
L
G
P
G
Site 36
S253
R
A
D
L
G
P
G
S
P
P
W
A
V
K
T
Site 37
T260
S
P
P
W
A
V
K
T
E
A
V
S
G
D
C
Site 38
S288
E
A
Q
D
R
H
P
S
P
S
G
V
G
N
R
Site 39
S290
Q
D
R
H
P
S
P
S
G
V
G
N
R
R
L
Site 40
S308
P
G
A
W
K
R
G
S
G
G
P
G
Y
L
L
Site 41
Y313
R
G
S
G
G
P
G
Y
L
L
T
P
P
P
H
Site 42
T316
G
G
P
G
Y
L
L
T
P
P
P
H
P
D
L
Site 43
S336
L
S
V
K
M
E
N
S
W
V
Q
S
P
P
G
Site 44
S340
M
E
N
S
W
V
Q
S
P
P
G
P
A
S
C
Site 45
S346
Q
S
P
P
G
P
A
S
C
Q
P
G
R
Q
P
Site 46
S355
Q
P
G
R
Q
P
L
S
P
S
A
T
G
D
T
Site 47
S357
G
R
Q
P
L
S
P
S
A
T
G
D
T
R
G
Site 48
T359
Q
P
L
S
P
S
A
T
G
D
T
R
G
V
P
Site 49
S369
T
R
G
V
P
Q
P
S
W
G
P
E
A
Q
A
Site 50
S378
G
P
E
A
Q
A
A
S
A
S
S
S
P
L
E
Site 51
S380
E
A
Q
A
A
S
A
S
S
S
P
L
E
A
L
Site 52
S382
Q
A
A
S
A
S
S
S
P
L
E
A
L
E
A
Site 53
S399
K
G
I
P
P
N
G
S
S
P
S
Q
L
P
P
Site 54
S400
G
I
P
P
N
G
S
S
P
S
Q
L
P
P
T
Site 55
S402
P
P
N
G
S
S
P
S
Q
L
P
P
T
S
C
Site 56
T407
S
P
S
Q
L
P
P
T
S
C
S
Q
N
P
Q
Site 57
S408
P
S
Q
L
P
P
T
S
C
S
Q
N
P
Q
P
Site 58
S410
Q
L
P
P
T
S
C
S
Q
N
P
Q
P
G
D
Site 59
S418
Q
N
P
Q
P
G
D
S
R
S
Q
K
P
E
L
Site 60
S420
P
Q
P
G
D
S
R
S
Q
K
P
E
L
Q
P
Site 61
S430
P
E
L
Q
P
H
R
S
H
S
E
E
A
T
R
Site 62
S432
L
Q
P
H
R
S
H
S
E
E
A
T
R
E
P
Site 63
T436
R
S
H
S
E
E
A
T
R
E
P
V
L
P
L
Site 64
S454
S
C
V
R
D
G
P
S
R
P
L
A
P
R
G
Site 65
T462
R
P
L
A
P
R
G
T
P
T
S
F
S
S
S
Site 66
T464
L
A
P
R
G
T
P
T
S
F
S
S
S
S
S
Site 67
S465
A
P
R
G
T
P
T
S
F
S
S
S
S
S
T
Site 68
S467
R
G
T
P
T
S
F
S
S
S
S
S
T
D
W
Site 69
S468
G
T
P
T
S
F
S
S
S
S
S
T
D
W
D
Site 70
S469
T
P
T
S
F
S
S
S
S
S
T
D
W
D
L
Site 71
S470
P
T
S
F
S
S
S
S
S
T
D
W
D
L
D
Site 72
S471
T
S
F
S
S
S
S
S
T
D
W
D
L
D
F
Site 73
T472
S
F
S
S
S
S
S
T
D
W
D
L
D
F
G
Site 74
S480
D
W
D
L
D
F
G
S
P
V
G
N
Q
G
Q
Site 75
S493
G
Q
H
P
G
K
G
S
P
P
G
S
S
P
L
Site 76
S497
G
K
G
S
P
P
G
S
S
P
L
Q
G
L
E
Site 77
S498
K
G
S
P
P
G
S
S
P
L
Q
G
L
E
N
Site 78
S522
L
R
P
A
W
P
C
S
S
A
A
D
R
G
P
Site 79
S523
R
P
A
W
P
C
S
S
A
A
D
R
G
P
R
Site 80
T538
R
A
E
P
R
N
W
T
A
D
K
E
G
L
R
Site 81
S551
L
R
A
E
A
C
E
S
A
R
L
G
Q
G
R
Site 82
T563
Q
G
R
G
E
A
P
T
R
S
L
H
L
V
S
Site 83
S565
R
G
E
A
P
T
R
S
L
H
L
V
S
P
Q
Site 84
S570
T
R
S
L
H
L
V
S
P
Q
V
F
T
S
S
Site 85
S577
S
P
Q
V
F
T
S
S
C
V
P
A
C
H
Q
Site 86
S605
W
R
W
L
P
E
G
S
A
P
K
P
S
P
L
Site 87
S610
E
G
S
A
P
K
P
S
P
L
H
C
L
E
S
Site 88
S637
F
A
C
V
G
G
P
S
P
S
P
S
P
G
S
Site 89
S639
C
V
G
G
P
S
P
S
P
S
P
G
S
S
S
Site 90
S641
G
G
P
S
P
S
P
S
P
G
S
S
S
S
F
Site 91
S644
S
P
S
P
S
P
G
S
S
S
S
F
S
G
S
Site 92
S645
P
S
P
S
P
G
S
S
S
S
F
S
G
S
E
Site 93
S646
S
P
S
P
G
S
S
S
S
F
S
G
S
E
G
Site 94
S647
P
S
P
G
S
S
S
S
F
S
G
S
E
G
E
Site 95
S649
P
G
S
S
S
S
F
S
G
S
E
G
E
D
P
Site 96
S651
S
S
S
S
F
S
G
S
E
G
E
D
P
R
P
Site 97
S675
Q
E
R
D
R
L
P
S
C
K
P
P
V
P
L
Site 98
S683
C
K
P
P
V
P
L
S
P
C
P
G
G
T
P
Site 99
T689
L
S
P
C
P
G
G
T
P
A
G
S
S
G
G
Site 100
S693
P
G
G
T
P
A
G
S
S
G
G
S
P
G
E
Site 101
S694
G
G
T
P
A
G
S
S
G
G
S
P
G
E
D
Site 102
S697
P
A
G
S
S
G
G
S
P
G
E
D
P
R
R
Site 103
T705
P
G
E
D
P
R
R
T
E
P
R
Y
C
S
G
Site 104
Y709
P
R
R
T
E
P
R
Y
C
S
G
L
G
A
G
Site 105
S711
R
T
E
P
R
Y
C
S
G
L
G
A
G
T
A
Site 106
S725
A
Q
D
P
C
P
V
S
Q
L
E
K
R
P
R
Site 107
S734
L
E
K
R
P
R
V
S
E
A
S
R
G
L
E
Site 108
S737
R
P
R
V
S
E
A
S
R
G
L
E
L
G
H
Site 109
T753
R
P
R
V
A
A
K
T
H
E
R
L
L
P
Q
Site 110
S767
Q
G
P
P
E
L
P
S
E
S
P
P
P
E
L
Site 111
S769
P
P
E
L
P
S
E
S
P
P
P
E
L
P
P
Site 112
S787
A
P
P
V
L
P
A
S
S
L
Q
P
P
C
H
Site 113
S805
P
L
Q
Q
E
L
H
S
L
G
A
A
L
A
E
Site 114
Y874
P
G
H
R
H
L
P
Y
W
R
Q
K
G
P
T
Site 115
T881
Y
W
R
Q
K
G
P
T
R
P
K
P
K
I
L
Site 116
S894
I
L
R
G
Q
G
E
S
C
R
A
G
D
L
Q
Site 117
T907
L
Q
G
L
S
R
G
T
A
R
R
A
R
P
L
Site 118
S929
E
P
P
G
L
H
C
S
S
S
Q
Q
L
L
S
Site 119
S930
P
P
G
L
H
C
S
S
S
Q
Q
L
L
S
S
Site 120
S931
P
G
L
H
C
S
S
S
Q
Q
L
L
S
S
T
Site 121
S936
S
S
S
Q
Q
L
L
S
S
T
P
S
C
H
A
Site 122
S937
S
S
Q
Q
L
L
S
S
T
P
S
C
H
A
A
Site 123
T938
S
Q
Q
L
L
S
S
T
P
S
C
H
A
A
P
Site 124
S940
Q
L
L
S
S
T
P
S
C
H
A
A
P
P
A
Site 125
S959
A
H
T
G
G
H
Q
S
P
L
P
P
L
V
P
Site 126
T987
S
A
D
A
D
V
P
T
S
G
V
A
P
D
G
Site 127
S1003
P
E
R
P
K
E
P
S
S
L
L
G
G
V
Q
Site 128
S1004
E
R
P
K
E
P
S
S
L
L
G
G
V
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation