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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGSL1
Full Name:
Regulator of G-protein signaling protein-like
Alias:
Type:
Mass (Da):
125688
Number AA:
1076
UniProt ID:
A5PLK6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
S
L
P
V
F
G
Q
T
P
F
Y
T
V
E
N
Site 2
Y40
V
F
G
Q
T
P
F
Y
T
V
E
N
S
Q
W
Site 3
T41
F
G
Q
T
P
F
Y
T
V
E
N
S
Q
W
S
Site 4
T66
A
K
Y
K
G
L
L
T
W
L
E
K
C
R
L
Site 5
S97
E
F
I
S
F
I
K
S
P
E
G
G
E
E
L
Site 6
S130
E
V
R
D
Y
Y
L
S
L
L
L
M
L
R
A
Site 7
T148
Q
E
G
S
R
V
V
T
L
C
N
M
N
I
K
Site 8
S161
I
K
S
L
L
N
L
S
I
W
H
P
N
Q
S
Site 9
S168
S
I
W
H
P
N
Q
S
T
T
R
R
E
I
L
Site 10
T169
I
W
H
P
N
Q
S
T
T
R
R
E
I
L
S
Site 11
S176
T
T
R
R
E
I
L
S
H
M
Q
K
V
A
L
Site 12
Y189
A
L
F
K
L
Q
S
Y
W
L
P
N
F
Y
T
Site 13
Y215
C
H
G
L
M
Q
E
Y
E
T
R
L
Y
S
V
Site 14
Y220
Q
E
Y
E
T
R
L
Y
S
V
C
Y
T
H
I
Site 15
S247
H
H
F
Q
K
R
Y
S
S
R
K
A
K
R
K
Site 16
S248
H
F
Q
K
R
Y
S
S
R
K
A
K
R
K
M
Site 17
S263
W
Q
L
V
D
P
D
S
W
S
L
E
M
D
L
Site 18
S265
L
V
D
P
D
S
W
S
L
E
M
D
L
K
P
Site 19
S300
P
S
L
K
M
A
S
S
K
E
T
R
I
S
S
Site 20
T303
K
M
A
S
S
K
E
T
R
I
S
S
L
E
K
Site 21
S306
S
S
K
E
T
R
I
S
S
L
E
K
D
M
H
Site 22
S307
S
K
E
T
R
I
S
S
L
E
K
D
M
H
Y
Site 23
Y314
S
L
E
K
D
M
H
Y
A
K
I
S
S
M
E
Site 24
S326
S
M
E
N
K
A
K
S
H
L
H
M
E
A
P
Site 25
S364
I
Q
K
A
I
K
Q
S
F
S
L
G
Y
I
H
Site 26
S411
Q
D
L
Q
H
F
L
S
V
L
L
N
N
K
K
Site 27
Y436
G
D
R
I
C
E
L
Y
L
N
E
Q
I
G
P
Site 28
S449
G
P
C
L
P
L
K
S
Q
T
I
Q
G
L
K
Site 29
T451
C
L
P
L
K
S
Q
T
I
Q
G
L
K
E
L
Site 30
Y483
C
K
M
L
S
P
W
Y
D
E
F
L
D
E
E
Site 31
Y492
E
F
L
D
E
E
D
Y
W
F
L
L
F
T
T
Site 32
S505
T
T
Q
N
R
F
I
S
S
R
Q
H
K
R
E
Site 33
Y523
K
E
E
N
I
L
L
Y
K
R
I
Q
Q
S
L
Site 34
S529
L
Y
K
R
I
Q
Q
S
L
E
L
S
Q
A
L
Site 35
S533
I
Q
Q
S
L
E
L
S
Q
A
L
A
D
M
K
Site 36
Y544
A
D
M
K
E
M
D
Y
R
Q
W
R
K
I
A
Site 37
S560
E
D
L
K
Q
G
G
S
L
Q
V
E
L
T
S
Site 38
S578
L
T
D
I
T
K
M
S
F
E
E
L
C
Y
K
Site 39
Y584
M
S
F
E
E
L
C
Y
K
N
P
K
M
A
I
Site 40
Y598
I
Q
K
I
S
D
D
Y
K
I
Y
C
E
K
A
Site 41
Y601
I
S
D
D
Y
K
I
Y
C
E
K
A
P
K
I
Site 42
T620
E
I
I
K
E
T
K
T
V
S
R
S
N
R
K
Site 43
S622
I
K
E
T
K
T
V
S
R
S
N
R
K
M
S
Site 44
S624
E
T
K
T
V
S
R
S
N
R
K
M
S
L
L
Site 45
S629
S
R
S
N
R
K
M
S
L
L
K
R
T
L
V
Site 46
T634
K
M
S
L
L
K
R
T
L
V
R
K
P
S
M
Site 47
S640
R
T
L
V
R
K
P
S
M
R
P
R
N
L
T
Site 48
T647
S
M
R
P
R
N
L
T
E
V
L
L
N
T
Q
Site 49
S692
T
N
E
K
I
C
K
S
L
I
E
N
V
I
K
Site 50
S707
T
F
F
Q
G
Q
L
S
P
E
E
M
L
Q
C
Site 51
S724
P
I
I
K
E
I
A
S
M
R
H
V
T
T
S
Site 52
S731
S
M
R
H
V
T
T
S
T
L
L
T
L
Q
G
Site 53
Y752
E
E
K
W
F
K
D
Y
Q
D
L
F
P
P
H
Site 54
S772
V
Q
S
E
V
Q
I
S
S
R
K
P
S
K
I
Site 55
S773
Q
S
E
V
Q
I
S
S
R
K
P
S
K
I
V
Site 56
S777
Q
I
S
S
R
K
P
S
K
I
V
S
T
Y
L
Site 57
S781
R
K
P
S
K
I
V
S
T
Y
L
Q
E
S
Q
Site 58
Y783
P
S
K
I
V
S
T
Y
L
Q
E
S
Q
K
K
Site 59
S787
V
S
T
Y
L
Q
E
S
Q
K
K
G
W
M
R
Site 60
Y805
F
I
R
S
F
C
K
Y
R
R
F
M
L
N
P
Site 61
S813
R
R
F
M
L
N
P
S
K
R
Q
E
F
E
D
Site 62
Y821
K
R
Q
E
F
E
D
Y
L
H
Q
E
M
Q
N
Site 63
S829
L
H
Q
E
M
Q
N
S
K
E
N
F
T
T
A
Site 64
T835
N
S
K
E
N
F
T
T
A
H
N
T
S
G
R
Site 65
S840
F
T
T
A
H
N
T
S
G
R
S
A
P
P
S
Site 66
S843
A
H
N
T
S
G
R
S
A
P
P
S
T
N
V
Site 67
S847
S
G
R
S
A
P
P
S
T
N
V
R
S
A
D
Site 68
T848
G
R
S
A
P
P
S
T
N
V
R
S
A
D
Q
Site 69
Y883
N
F
A
I
N
D
L
Y
F
F
S
E
M
E
K
Site 70
S896
E
K
F
N
D
L
V
S
S
A
H
M
L
Q
V
Site 71
S897
K
F
N
D
L
V
S
S
A
H
M
L
Q
V
N
Site 72
Y907
M
L
Q
V
N
R
A
Y
N
E
N
D
V
I
L
Site 73
Y988
F
W
K
A
T
R
S
Y
L
Q
Y
R
G
K
K
Site 74
Y991
A
T
R
S
Y
L
Q
Y
R
G
K
K
F
K
D
Site 75
S1001
K
K
F
K
D
R
K
S
P
P
K
S
T
D
K
Site 76
S1005
D
R
K
S
P
P
K
S
T
D
K
Y
P
F
S
Site 77
Y1009
P
P
K
S
T
D
K
Y
P
F
S
S
G
G
D
Site 78
S1012
S
T
D
K
Y
P
F
S
S
G
G
D
N
A
I
Site 79
S1039
Q
P
Q
R
E
A
I
S
S
V
Q
N
S
S
S
Site 80
S1040
P
Q
R
E
A
I
S
S
V
Q
N
S
S
S
S
Site 81
S1044
A
I
S
S
V
Q
N
S
S
S
S
K
L
T
Q
Site 82
S1045
I
S
S
V
Q
N
S
S
S
S
K
L
T
Q
P
Site 83
S1046
S
S
V
Q
N
S
S
S
S
K
L
T
Q
P
R
Site 84
S1047
S
V
Q
N
S
S
S
S
K
L
T
Q
P
R
L
Site 85
T1050
N
S
S
S
S
K
L
T
Q
P
R
L
V
V
S
Site 86
S1070
P
V
Q
G
Q
K
L
S
Y
I
K
K
E
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation