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Updated November 2019
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Protein Info
Short Name:
ANKRD34B
Full Name:
Ankyrin repeat domain-containing protein 34B
Alias:
Type:
Mass (Da):
56388
Number AA:
514
UniProt ID:
A5PLL1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
D
E
G
M
E
I
S
S
E
G
N
S
L
I
Site 2
S13
E
I
S
S
E
G
N
S
L
I
K
A
V
H
Q
Site 3
S21
L
I
K
A
V
H
Q
S
R
L
R
L
T
R
L
Site 4
T26
H
Q
S
R
L
R
L
T
R
L
L
L
E
G
G
Site 5
Y35
L
L
L
E
G
G
A
Y
I
N
E
S
N
D
R
Site 6
S39
G
G
A
Y
I
N
E
S
N
D
R
G
E
T
P
Site 7
T45
E
S
N
D
R
G
E
T
P
L
M
I
A
C
K
Site 8
S60
T
K
H
V
D
H
Q
S
V
S
K
A
K
M
V
Site 9
Y69
S
K
A
K
M
V
K
Y
L
L
E
N
N
A
D
Site 10
S83
D
P
N
I
Q
D
K
S
G
K
T
A
L
M
H
Site 11
S112
L
K
S
G
A
D
L
S
L
Q
D
H
S
S
Y
Site 12
S117
D
L
S
L
Q
D
H
S
S
Y
S
A
L
V
Y
Site 13
S118
L
S
L
Q
D
H
S
S
Y
S
A
L
V
Y
A
Site 14
Y124
S
S
Y
S
A
L
V
Y
A
I
N
S
E
D
T
Site 15
T133
I
N
S
E
D
T
E
T
L
K
V
L
L
S
A
Site 16
S139
E
T
L
K
V
L
L
S
A
C
K
A
K
G
K
Site 17
S156
I
I
I
T
T
A
K
S
P
C
G
K
H
T
T
Site 18
Y166
G
K
H
T
T
K
Q
Y
L
N
M
P
P
V
D
Site 19
S179
V
D
I
D
G
C
H
S
P
A
T
C
T
T
P
Site 20
T182
D
G
C
H
S
P
A
T
C
T
T
P
S
E
I
Site 21
T185
H
S
P
A
T
C
T
T
P
S
E
I
D
I
K
Site 22
T193
P
S
E
I
D
I
K
T
A
S
S
P
L
S
H
Site 23
S195
E
I
D
I
K
T
A
S
S
P
L
S
H
S
S
Site 24
S196
I
D
I
K
T
A
S
S
P
L
S
H
S
S
E
Site 25
S199
K
T
A
S
S
P
L
S
H
S
S
E
T
E
L
Site 26
S201
A
S
S
P
L
S
H
S
S
E
T
E
L
T
L
Site 27
S202
S
S
P
L
S
H
S
S
E
T
E
L
T
L
F
Site 28
T207
H
S
S
E
T
E
L
T
L
F
G
F
K
D
L
Site 29
S219
K
D
L
E
L
A
G
S
N
D
D
T
W
D
P
Site 30
T223
L
A
G
S
N
D
D
T
W
D
P
G
S
P
V
Site 31
S228
D
D
T
W
D
P
G
S
P
V
R
K
P
A
L
Site 32
S251
H
A
P
P
W
V
K
S
P
P
L
L
M
H
Q
Site 33
S263
M
H
Q
N
R
V
A
S
L
Q
E
E
L
Q
D
Site 34
T272
Q
E
E
L
Q
D
I
T
P
E
E
E
L
S
Y
Site 35
S278
I
T
P
E
E
E
L
S
Y
K
T
N
G
L
A
Site 36
Y279
T
P
E
E
E
L
S
Y
K
T
N
G
L
A
L
Site 37
S287
K
T
N
G
L
A
L
S
K
R
F
I
T
R
H
Site 38
T292
A
L
S
K
R
F
I
T
R
H
Q
S
I
D
V
Site 39
S296
R
F
I
T
R
H
Q
S
I
D
V
K
D
T
A
Site 40
S313
L
R
A
F
D
Q
A
S
S
R
K
M
S
Y
D
Site 41
S318
Q
A
S
S
R
K
M
S
Y
D
E
I
N
C
Q
Site 42
Y327
D
E
I
N
C
Q
S
Y
L
S
E
G
N
Q
Q
Site 43
S346
P
V
D
Q
D
P
D
S
N
Q
T
I
F
A
S
Site 44
S353
S
N
Q
T
I
F
A
S
T
L
R
S
I
V
Q
Site 45
T354
N
Q
T
I
F
A
S
T
L
R
S
I
V
Q
K
Site 46
Y369
R
N
L
G
A
N
H
Y
S
S
D
S
Q
L
S
Site 47
S370
N
L
G
A
N
H
Y
S
S
D
S
Q
L
S
A
Site 48
S371
L
G
A
N
H
Y
S
S
D
S
Q
L
S
A
G
Site 49
S373
A
N
H
Y
S
S
D
S
Q
L
S
A
G
L
T
Site 50
S376
Y
S
S
D
S
Q
L
S
A
G
L
T
P
P
T
Site 51
T380
S
Q
L
S
A
G
L
T
P
P
T
S
E
D
G
Site 52
S384
A
G
L
T
P
P
T
S
E
D
G
K
A
L
I
Site 53
S398
I
G
K
K
K
I
L
S
P
S
P
S
Q
L
S
Site 54
S400
K
K
K
I
L
S
P
S
P
S
Q
L
S
E
S
Site 55
S402
K
I
L
S
P
S
P
S
Q
L
S
E
S
K
E
Site 56
S405
S
P
S
P
S
Q
L
S
E
S
K
E
L
L
E
Site 57
S420
N
I
P
P
G
P
L
S
R
R
N
H
A
V
L
Site 58
S432
A
V
L
E
R
R
G
S
G
A
F
P
L
D
H
Site 59
S440
G
A
F
P
L
D
H
S
V
T
Q
T
R
Q
G
Site 60
T442
F
P
L
D
H
S
V
T
Q
T
R
Q
G
F
L
Site 61
T444
L
D
H
S
V
T
Q
T
R
Q
G
F
L
P
P
Site 62
S456
L
P
P
L
N
V
N
S
H
P
P
I
S
D
I
Site 63
S461
V
N
S
H
P
P
I
S
D
I
N
V
N
N
K
Site 64
S471
N
V
N
N
K
I
C
S
L
L
S
C
G
Q
K
Site 65
S493
I
F
P
K
E
F
K
S
K
K
M
L
L
R
R
Site 66
S502
K
M
L
L
R
R
Q
S
L
Q
T
E
Q
I
K
Site 67
T505
L
R
R
Q
S
L
Q
T
E
Q
I
K
Q
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation