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Updated November 2019
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Protein Info
Short Name:
BDP1
Full Name:
Transcription factor TFIIIB component B'' homolog
Alias:
DKFZp686L02246; Transcription factor IIIB 150; Transcription factor TFIIIB component B'' homologue
Type:
Mass (Da):
293878
Number AA:
2624
UniProt ID:
A6H8Y1
International Prot ID:
IPI00760877
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
F
R
R
A
R
L
S
V
K
P
N
V
R
P
Site 2
S22
P
G
V
G
A
R
G
S
T
A
S
N
P
Q
R
Site 3
T23
G
V
G
A
R
G
S
T
A
S
N
P
Q
R
G
Site 4
S25
G
A
R
G
S
T
A
S
N
P
Q
R
G
R
E
Site 5
S33
N
P
Q
R
G
R
E
S
P
R
P
P
E
P
A
Site 6
T41
P
R
P
P
E
P
A
T
D
S
A
S
K
P
A
Site 7
S43
P
P
E
P
A
T
D
S
A
S
K
P
A
E
P
Site 8
S45
E
P
A
T
D
S
A
S
K
P
A
E
P
T
D
Site 9
T51
A
S
K
P
A
E
P
T
D
V
P
T
V
D
F
Site 10
T55
A
E
P
T
D
V
P
T
V
D
F
G
G
A
E
Site 11
S70
P
Q
E
K
A
P
R
S
S
T
E
K
T
G
G
Site 12
S71
Q
E
K
A
P
R
S
S
T
E
K
T
G
G
D
Site 13
T72
E
K
A
P
R
S
S
T
E
K
T
G
G
D
N
Site 14
T75
P
R
S
S
T
E
K
T
G
G
D
N
D
V
E
Site 15
S84
G
D
N
D
V
E
E
S
S
R
S
S
S
T
V
Site 16
S85
D
N
D
V
E
E
S
S
R
S
S
S
T
V
S
Site 17
S87
D
V
E
E
S
S
R
S
S
S
T
V
S
Q
R
Site 18
S88
V
E
E
S
S
R
S
S
S
T
V
S
Q
R
R
Site 19
S89
E
E
S
S
R
S
S
S
T
V
S
Q
R
R
K
Site 20
T90
E
S
S
R
S
S
S
T
V
S
Q
R
R
K
R
Site 21
S92
S
R
S
S
S
T
V
S
Q
R
R
K
R
I
S
Site 22
S99
S
Q
R
R
K
R
I
S
S
T
S
S
L
V
K
Site 23
S100
Q
R
R
K
R
I
S
S
T
S
S
L
V
K
S
Site 24
T101
R
R
K
R
I
S
S
T
S
S
L
V
K
S
S
Site 25
S102
R
K
R
I
S
S
T
S
S
L
V
K
S
S
V
Site 26
S103
K
R
I
S
S
T
S
S
L
V
K
S
S
V
S
Site 27
S107
S
T
S
S
L
V
K
S
S
V
S
V
P
S
E
Site 28
S108
T
S
S
L
V
K
S
S
V
S
V
P
S
E
S
Site 29
S110
S
L
V
K
S
S
V
S
V
P
S
E
S
H
P
Site 30
S113
K
S
S
V
S
V
P
S
E
S
H
P
L
S
T
Site 31
S115
S
V
S
V
P
S
E
S
H
P
L
S
T
I
N
Site 32
S119
P
S
E
S
H
P
L
S
T
I
N
Q
E
A
P
Site 33
T133
P
Q
P
T
A
T
S
T
K
E
K
Q
P
C
S
Site 34
S140
T
K
E
K
Q
P
C
S
D
R
Y
R
I
Y
K
Site 35
Y143
K
Q
P
C
S
D
R
Y
R
I
Y
K
A
Q
K
Site 36
Y146
C
S
D
R
Y
R
I
Y
K
A
Q
K
L
R
E
Site 37
Y170
K
K
Q
W
K
N
K
Y
A
I
N
E
S
Q
R
Site 38
S175
N
K
Y
A
I
N
E
S
Q
R
P
P
D
R
S
Site 39
S182
S
Q
R
P
P
D
R
S
K
M
T
M
R
D
F
Site 40
Y191
M
T
M
R
D
F
I
Y
Y
L
P
D
N
N
P
Site 41
Y192
T
M
R
D
F
I
Y
Y
L
P
D
N
N
P
M
Site 42
T200
L
P
D
N
N
P
M
T
S
S
L
E
Q
E
K
Site 43
T209
S
L
E
Q
E
K
K
T
E
K
P
S
T
P
V
Site 44
S213
E
K
K
T
E
K
P
S
T
P
V
Q
T
R
E
Site 45
T214
K
K
T
E
K
P
S
T
P
V
Q
T
R
E
Q
Site 46
T226
R
E
Q
E
G
K
S
T
P
N
A
E
D
N
E
Site 47
T264
I
L
D
E
E
S
L
T
V
E
V
L
R
T
K
Site 48
S287
D
P
I
F
E
R
G
S
T
T
T
Y
S
S
F
Site 49
T288
P
I
F
E
R
G
S
T
T
T
Y
S
S
F
R
Site 50
T289
I
F
E
R
G
S
T
T
T
Y
S
S
F
R
K
Site 51
T290
F
E
R
G
S
T
T
T
Y
S
S
F
R
K
N
Site 52
Y291
E
R
G
S
T
T
T
Y
S
S
F
R
K
N
Y
Site 53
S292
R
G
S
T
T
T
Y
S
S
F
R
K
N
Y
Y
Site 54
S293
G
S
T
T
T
Y
S
S
F
R
K
N
Y
Y
S
Site 55
Y298
Y
S
S
F
R
K
N
Y
Y
S
K
P
W
S
N
Site 56
Y299
S
S
F
R
K
N
Y
Y
S
K
P
W
S
N
K
Site 57
S300
S
F
R
K
N
Y
Y
S
K
P
W
S
N
K
E
Site 58
S385
E
E
K
R
K
Q
K
S
V
K
N
H
S
L
K
Site 59
S390
Q
K
S
V
K
N
H
S
L
K
E
K
K
S
T
Site 60
S396
H
S
L
K
E
K
K
S
T
K
P
R
K
N
V
Site 61
T397
S
L
K
E
K
K
S
T
K
P
R
K
N
V
K
Site 62
S420
V
N
N
D
P
D
E
S
M
S
S
R
I
S
D
Site 63
S422
N
D
P
D
E
S
M
S
S
R
I
S
D
T
E
Site 64
S423
D
P
D
E
S
M
S
S
R
I
S
D
T
E
R
Site 65
S426
E
S
M
S
S
R
I
S
D
T
E
R
S
Q
K
Site 66
T428
M
S
S
R
I
S
D
T
E
R
S
Q
K
D
A
Site 67
S431
R
I
S
D
T
E
R
S
Q
K
D
A
Q
T
V
Site 68
T437
R
S
Q
K
D
A
Q
T
V
E
E
E
S
L
T
Site 69
S442
A
Q
T
V
E
E
E
S
L
T
L
S
R
E
D
Site 70
T444
T
V
E
E
E
S
L
T
L
S
R
E
D
A
E
Site 71
S446
E
E
E
S
L
T
L
S
R
E
D
A
E
Q
V
Site 72
T485
N
N
L
L
E
N
A
T
V
Q
A
G
P
S
K
Site 73
S513
E
L
K
E
G
E
C
S
K
E
Q
M
L
S
C
Site 74
S545
K
R
T
D
P
I
L
S
L
S
N
Q
Q
D
A
Site 75
S547
T
D
P
I
L
S
L
S
N
Q
Q
D
A
T
S
Site 76
S554
S
N
Q
Q
D
A
T
S
V
A
T
E
S
S
E
Site 77
S559
A
T
S
V
A
T
E
S
S
E
S
S
T
S
D
Site 78
S560
T
S
V
A
T
E
S
S
E
S
S
T
S
D
L
Site 79
S562
V
A
T
E
S
S
E
S
S
T
S
D
L
P
S
Site 80
S563
A
T
E
S
S
E
S
S
T
S
D
L
P
S
F
Site 81
T564
T
E
S
S
E
S
S
T
S
D
L
P
S
F
E
Site 82
S565
E
S
S
E
S
S
T
S
D
L
P
S
F
E
V
Site 83
S569
S
S
T
S
D
L
P
S
F
E
V
G
I
R
A
Site 84
T605
N
S
L
E
I
D
Q
T
E
N
V
K
P
M
L
Site 85
S624
Q
R
P
K
P
N
L
S
R
A
G
K
K
S
V
Site 86
S630
L
S
R
A
G
K
K
S
V
L
S
Q
G
K
T
Site 87
S633
A
G
K
K
S
V
L
S
Q
G
K
T
E
S
E
Site 88
T637
S
V
L
S
Q
G
K
T
E
S
E
S
K
N
S
Site 89
S639
L
S
Q
G
K
T
E
S
E
S
K
N
S
H
S
Site 90
S641
Q
G
K
T
E
S
E
S
K
N
S
H
S
K
T
Site 91
S644
T
E
S
E
S
K
N
S
H
S
K
T
S
V
E
Site 92
S646
S
E
S
K
N
S
H
S
K
T
S
V
E
K
N
Site 93
T648
S
K
N
S
H
S
K
T
S
V
E
K
N
H
V
Site 94
T670
L
D
I
L
R
M
E
T
T
E
R
E
N
P
E
Site 95
T671
D
I
L
R
M
E
T
T
E
R
E
N
P
E
A
Site 96
T680
R
E
N
P
E
A
E
T
V
S
V
L
G
E
K
Site 97
S682
N
P
E
A
E
T
V
S
V
L
G
E
K
N
C
Site 98
S694
K
N
C
L
Q
E
G
S
Q
L
K
A
L
R
P
Site 99
S727
E
R
K
E
I
L
I
S
Q
E
E
I
G
A
N
Site 100
T748
E
S
C
A
D
R
D
T
P
Q
H
M
E
D
Q
Site 101
S774
L
Q
P
E
K
N
D
S
F
Q
N
V
Q
P
D
Site 102
S791
K
V
L
N
E
C
L
S
V
Q
E
N
N
K
A
Site 103
T822
K
P
N
I
G
R
G
T
G
R
R
E
I
S
S
Site 104
S828
G
T
G
R
R
E
I
S
S
K
E
E
V
L
E
Site 105
S829
T
G
R
R
E
I
S
S
K
E
E
V
L
E
K
Site 106
S840
V
L
E
K
I
L
V
S
G
E
M
A
A
A
L
Site 107
T850
M
A
A
A
L
R
E
T
V
R
L
D
T
S
P
Site 108
T855
R
E
T
V
R
L
D
T
S
P
K
E
M
V
P
Site 109
S856
E
T
V
R
L
D
T
S
P
K
E
M
V
P
A
Site 110
S872
I
N
T
K
E
M
Q
S
D
L
K
E
T
G
R
Site 111
S883
E
T
G
R
R
A
I
S
P
R
E
K
I
L
D
Site 112
T895
I
L
D
V
I
D
D
T
I
E
M
E
T
G
L
Site 113
T900
D
D
T
I
E
M
E
T
G
L
K
A
M
G
R
Site 114
T915
E
I
C
L
R
E
K
T
P
E
V
I
D
A
T
Site 115
S938
E
A
G
R
R
E
I
S
P
Q
K
N
G
P
E
Site 116
S964
L
K
A
T
G
N
E
S
S
P
R
E
K
T
P
Site 117
S965
K
A
T
G
N
E
S
S
P
R
E
K
T
P
E
Site 118
T970
E
S
S
P
R
E
K
T
P
E
V
T
D
A
T
Site 119
T977
T
P
E
V
T
D
A
T
E
E
I
D
K
N
L
Site 120
T987
I
D
K
N
L
E
E
T
G
R
R
K
I
S
P
Site 121
S993
E
T
G
R
R
K
I
S
P
R
E
N
G
P
E
Site 122
T1015
M
E
T
D
L
N
A
T
G
R
E
S
S
P
R
Site 123
S1019
L
N
A
T
G
R
E
S
S
P
R
E
K
T
P
Site 124
S1020
N
A
T
G
R
E
S
S
P
R
E
K
T
P
E
Site 125
T1025
E
S
S
P
R
E
K
T
P
E
V
I
D
A
T
Site 126
T1032
T
P
E
V
I
D
A
T
E
E
I
D
L
E
E
Site 127
T1040
E
E
I
D
L
E
E
T
E
R
E
V
S
P
Q
Site 128
S1045
E
E
T
E
R
E
V
S
P
Q
E
N
G
L
E
Site 129
T1067
M
E
T
D
L
K
A
T
G
R
D
S
F
P
R
Site 130
S1071
L
K
A
T
G
R
D
S
F
P
R
G
K
T
P
Site 131
T1077
D
S
F
P
R
G
K
T
P
E
V
I
D
A
I
Site 132
S1099
E
E
T
E
R
E
I
S
P
Q
E
N
G
L
E
Site 133
S1126
K
A
T
G
R
E
I
S
P
R
E
K
T
P
E
Site 134
T1131
E
I
S
P
R
E
K
T
P
E
V
I
D
A
T
Site 135
T1148
I
D
K
D
L
E
E
T
G
R
R
E
I
S
P
Site 136
S1154
E
T
G
R
R
E
I
S
P
E
E
N
G
P
E
Site 137
T1175
E
M
E
T
D
L
K
T
T
G
R
E
G
S
S
Site 138
T1176
M
E
T
D
L
K
T
T
G
R
E
G
S
S
R
Site 139
S1181
K
T
T
G
R
E
G
S
S
R
E
K
T
R
E
Site 140
S1182
T
T
G
R
E
G
S
S
R
E
K
T
R
E
V
Site 141
T1186
E
G
S
S
R
E
K
T
R
E
V
I
D
A
A
Site 142
T1198
D
A
A
E
V
I
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S2471
P
Q
D
E
M
I
V
S
D
K
E
E
R
T
D
Site 295
S2483
R
T
D
A
A
P
K
S
Q
Q
M
D
S
R
T
Site 296
S2488
P
K
S
Q
Q
M
D
S
R
T
S
S
S
K
A
Site 297
T2490
S
Q
Q
M
D
S
R
T
S
S
S
K
A
S
L
Site 298
S2491
Q
Q
M
D
S
R
T
S
S
S
K
A
S
L
S
Site 299
S2492
Q
M
D
S
R
T
S
S
S
K
A
S
L
S
R
Site 300
S2493
M
D
S
R
T
S
S
S
K
A
S
L
S
R
P
Site 301
S2496
R
T
S
S
S
K
A
S
L
S
R
P
G
R
R
Site 302
S2498
S
S
S
K
A
S
L
S
R
P
G
R
R
P
L
Site 303
S2509
R
R
P
L
G
F
L
S
L
I
C
S
K
N
S
Site 304
S2513
G
F
L
S
L
I
C
S
K
N
S
L
E
S
D
Site 305
S2516
S
L
I
C
S
K
N
S
L
E
S
D
E
P
M
Site 306
S2519
C
S
K
N
S
L
E
S
D
E
P
M
Q
V
H
Site 307
S2545
L
R
K
K
L
K
R
S
N
P
F
N
E
S
Q
Site 308
S2551
R
S
N
P
F
N
E
S
Q
E
K
N
R
E
S
Site 309
S2558
S
Q
E
K
N
R
E
S
S
D
L
L
P
S
P
Site 310
S2559
Q
E
K
N
R
E
S
S
D
L
L
P
S
P
S
Site 311
S2564
E
S
S
D
L
L
P
S
P
S
V
I
T
T
Q
Site 312
S2566
S
D
L
L
P
S
P
S
V
I
T
T
Q
S
E
Site 313
T2570
P
S
P
S
V
I
T
T
Q
S
E
N
I
S
S
Site 314
S2572
P
S
V
I
T
T
Q
S
E
N
I
S
S
S
A
Site 315
S2576
T
T
Q
S
E
N
I
S
S
S
A
T
Q
V
S
Site 316
S2577
T
Q
S
E
N
I
S
S
S
A
T
Q
V
S
C
Site 317
S2578
Q
S
E
N
I
S
S
S
A
T
Q
V
S
C
D
Site 318
T2580
E
N
I
S
S
S
A
T
Q
V
S
C
D
Q
P
Site 319
S2583
S
S
S
A
T
Q
V
S
C
D
Q
P
L
L
K
Site 320
S2595
L
L
K
E
G
Y
K
S
A
Q
K
R
A
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation