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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL33
Full Name:
Kelch-like protein 33
Alias:
Type:
Mass (Da):
57810
Number AA:
533
UniProt ID:
A6NCF5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
L
L
S
G
M
R
E
S
Q
G
T
E
V
S
L
Site 2
T12
G
M
R
E
S
Q
G
T
E
V
S
L
R
T
I
Site 3
S15
E
S
Q
G
T
E
V
S
L
R
T
I
S
T
Q
Site 4
S20
E
V
S
L
R
T
I
S
T
Q
D
L
R
L
L
Site 5
Y53
A
A
Q
A
A
L
Q
Y
Q
S
S
S
C
L
D
Site 6
S56
A
A
L
Q
Y
Q
S
S
S
C
L
D
L
C
Q
Site 7
S57
A
L
Q
Y
Q
S
S
S
C
L
D
L
C
Q
K
Site 8
S92
P
G
L
E
R
L
W
S
K
A
R
H
Y
L
L
Site 9
Y97
L
W
S
K
A
R
H
Y
L
L
T
H
L
P
A
Site 10
S125
C
L
A
E
L
L
D
S
D
E
L
H
V
Q
E
Site 11
S153
A
N
P
E
T
Q
E
S
E
A
K
A
L
L
R
Site 12
S168
C
V
R
F
G
R
M
S
T
R
E
L
R
R
V
Site 13
T169
V
R
F
G
R
M
S
T
R
E
L
R
R
V
R
Site 14
S229
D
M
A
L
R
Q
P
S
R
A
V
W
W
A
R
Site 15
S268
R
F
R
H
G
A
A
S
L
A
G
S
E
L
Y
Site 16
Y283
V
C
G
G
Q
D
F
Y
S
H
S
N
T
L
A
Site 17
S284
C
G
G
Q
D
F
Y
S
H
S
N
T
L
A
S
Site 18
S286
G
Q
D
F
Y
S
H
S
N
T
L
A
S
T
L
Site 19
T288
D
F
Y
S
H
S
N
T
L
A
S
T
L
R
W
Site 20
T292
H
S
N
T
L
A
S
T
L
R
W
E
P
S
Q
Site 21
S298
S
T
L
R
W
E
P
S
Q
E
D
W
E
E
M
Site 22
S309
W
E
E
M
A
P
L
S
Q
A
R
S
L
F
S
Site 23
Y325
V
A
L
D
G
K
L
Y
A
L
G
G
R
H
N
Site 24
S338
H
N
D
V
A
L
D
S
V
E
T
Y
N
P
E
Site 25
T341
V
A
L
D
S
V
E
T
Y
N
P
E
L
N
V
Site 26
Y342
A
L
D
S
V
E
T
Y
N
P
E
L
N
V
W
Site 27
S386
G
T
G
Q
Y
L
A
S
L
M
H
Y
D
P
K
Site 28
Y390
Y
L
A
S
L
M
H
Y
D
P
K
L
E
K
P
Site 29
T399
P
K
L
E
K
P
G
T
F
L
S
P
M
G
V
Site 30
S402
E
K
P
G
T
F
L
S
P
M
G
V
P
R
A
Site 31
S434
G
E
T
E
D
L
L
S
F
E
A
Y
E
L
R
Site 32
Y438
D
L
L
S
F
E
A
Y
E
L
R
T
D
S
W
Site 33
T442
F
E
A
Y
E
L
R
T
D
S
W
T
H
L
A
Site 34
S444
A
Y
E
L
R
T
D
S
W
T
H
L
A
P
L
Site 35
T446
E
L
R
T
D
S
W
T
H
L
A
P
L
P
S
Site 36
S453
T
H
L
A
P
L
P
S
P
H
V
G
A
A
S
Site 37
T477
L
G
G
Y
S
H
R
T
Y
A
L
S
H
L
I
Site 38
Y478
G
G
Y
S
H
R
T
Y
A
L
S
H
L
I
H
Site 39
T525
Q
H
I
A
L
V
P
T
P
H
Q
T
K
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation