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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
4432412L15Rik
Full Name:
Paralemmin-3
Alias:
Type:
Mass (Da):
71700
Number AA:
UniProt ID:
A6NDB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005737
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005524
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
A
E
S
S
L
Y
R
Q
R
L
E
V
I
Site 2
S45
V
E
R
L
K
R
K
S
L
R
E
R
W
L
M
Site 3
S62
A
A
A
V
P
E
P
S
E
D
P
T
S
K
D
Site 4
T66
P
E
P
S
E
D
P
T
S
K
D
P
Q
S
P
Site 5
S67
E
P
S
E
D
P
T
S
K
D
P
Q
S
P
E
Site 6
S72
P
T
S
K
D
P
Q
S
P
E
G
Q
A
Q
A
Site 7
S87
R
I
R
N
L
E
D
S
L
F
T
L
Q
S
Q
Site 8
S93
D
S
L
F
T
L
Q
S
Q
L
Q
L
L
Q
S
Site 9
S100
S
Q
L
Q
L
L
Q
S
A
S
T
G
A
Q
H
Site 10
S102
L
Q
L
L
Q
S
A
S
T
G
A
Q
H
K
P
Site 11
S110
T
G
A
Q
H
K
P
S
G
R
P
S
W
R
R
Site 12
S114
H
K
P
S
G
R
P
S
W
R
R
Q
G
H
R
Site 13
S124
R
Q
G
H
R
P
L
S
Q
S
I
V
E
A
G
Site 14
S126
G
H
R
P
L
S
Q
S
I
V
E
A
G
S
V
Site 15
T136
E
A
G
S
V
G
Q
T
D
L
N
K
R
A
S
Site 16
S143
T
D
L
N
K
R
A
S
L
P
A
G
L
V
G
Site 17
T151
L
P
A
G
L
V
G
T
P
P
E
S
P
S
E
Site 18
S155
L
V
G
T
P
P
E
S
P
S
E
P
R
E
D
Site 19
S157
G
T
P
P
E
S
P
S
E
P
R
E
D
V
L
Site 20
S181
P
G
A
A
G
D
S
S
E
A
N
G
P
C
P
Site 21
S189
E
A
N
G
P
C
P
S
P
I
P
T
P
E
Q
Site 22
T193
P
C
P
S
P
I
P
T
P
E
Q
G
L
S
Q
Site 23
S199
P
T
P
E
Q
G
L
S
Q
R
A
V
P
S
E
Site 24
T228
V
W
E
G
L
R
A
T
E
D
C
A
T
G
A
Site 25
T233
R
A
T
E
D
C
A
T
G
A
T
G
P
E
L
Site 26
S260
G
D
R
K
G
A
G
S
L
E
L
P
A
W
V
Site 27
T301
R
V
P
E
V
V
Q
T
S
S
P
R
L
Q
E
Site 28
S302
V
P
E
V
V
Q
T
S
S
P
R
L
Q
E
R
Site 29
S303
P
E
V
V
Q
T
S
S
P
R
L
Q
E
R
L
Site 30
S315
E
R
L
E
A
A
A
S
I
E
G
E
D
V
P
Site 31
S325
G
E
D
V
P
Q
G
S
P
E
G
D
G
Q
G
Site 32
S334
E
G
D
G
Q
G
G
S
G
G
E
E
G
S
F
Site 33
S340
G
S
G
G
E
E
G
S
F
I
W
V
E
R
V
Site 34
T348
F
I
W
V
E
R
V
T
L
S
E
E
W
E
E
Site 35
S350
W
V
E
R
V
T
L
S
E
E
W
E
E
L
L
Site 36
S375
G
R
E
R
G
D
E
S
P
L
G
A
E
G
A
Site 37
T384
L
G
A
E
G
A
K
T
G
G
G
E
E
T
W
Site 38
S401
E
K
R
K
A
E
E
S
M
G
I
G
S
E
E
Site 39
S406
E
E
S
M
G
I
G
S
E
E
K
P
G
T
G
Site 40
T412
G
S
E
E
K
P
G
T
G
R
D
E
A
E
M
Site 41
S420
G
R
D
E
A
E
M
S
P
V
V
E
R
K
G
Site 42
S439
L
E
L
E
S
R
G
S
A
E
K
L
G
T
E
Site 43
T445
G
S
A
E
K
L
G
T
E
R
E
G
G
E
E
Site 44
T500
G
E
E
E
P
E
A
T
K
E
P
L
E
A
E
Site 45
T514
E
R
K
G
G
E
E
T
L
E
A
E
K
R
G
Site 46
S525
E
K
R
G
G
E
E
S
L
E
T
E
K
T
Q
Site 47
T528
G
G
E
E
S
L
E
T
E
K
T
Q
G
T
E
Site 48
T531
E
S
L
E
T
E
K
T
Q
G
T
E
G
D
L
Site 49
S544
D
L
N
L
E
Q
G
S
R
E
G
S
E
S
Q
Site 50
S548
E
Q
G
S
R
E
G
S
E
S
Q
A
E
E
M
Site 51
S550
G
S
R
E
G
S
E
S
Q
A
E
E
M
N
E
Site 52
T606
Q
G
P
L
G
D
A
T
P
L
L
A
E
T
P
Site 53
T612
A
T
P
L
L
A
E
T
P
A
P
E
Q
P
A
Site 54
S631
L
L
Q
G
E
G
P
S
A
N
P
S
A
H
P
Site 55
S635
E
G
P
S
A
N
P
S
A
H
P
V
P
T
Y
Site 56
T641
P
S
A
H
P
V
P
T
Y
A
P
A
R
Q
P
Site 57
Y642
S
A
H
P
V
P
T
Y
A
P
A
R
Q
P
E
Site 58
S651
P
A
R
Q
P
E
P
S
A
P
T
E
G
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation