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Updated November 2019
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Protein Info
Short Name:
NBPF21
Full Name:
Neuroblastoma breakpoint family member 21
Alias:
Type:
Mass (Da):
68210
Number AA:
598
UniProt ID:
A6NDD8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
V
V
S
A
G
P
W
S
S
E
K
A
E
M
N
Site 2
S10
V
S
A
G
P
W
S
S
E
K
A
E
M
N
I
Site 3
Y60
N
R
H
K
K
Y
K
Y
E
E
C
K
D
L
I
Site 4
Y95
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
S
Q
Site 5
S101
Q
Y
K
V
L
V
H
S
Q
E
R
E
L
T
Q
Site 6
T107
H
S
Q
E
R
E
L
T
Q
L
R
E
K
L
R
Site 7
S120
L
R
E
G
R
D
A
S
R
S
L
N
E
H
L
Site 8
S122
E
G
R
D
A
S
R
S
L
N
E
H
L
Q
A
Site 9
T132
E
H
L
Q
A
L
L
T
P
D
E
P
D
K
S
Site 10
S139
T
P
D
E
P
D
K
S
Q
G
Q
D
L
Q
E
Site 11
S163
Q
H
L
V
Q
K
L
S
P
E
N
D
E
D
E
Site 12
S186
D
E
K
V
L
E
S
S
A
P
R
E
V
Q
K
Site 13
S203
E
S
K
V
P
E
D
S
L
E
E
C
A
I
T
Site 14
T210
S
L
E
E
C
A
I
T
C
S
N
S
H
G
P
Site 15
T230
P
H
K
N
I
K
I
T
F
E
E
D
K
V
N
Site 16
S239
E
E
D
K
V
N
S
S
L
V
V
D
R
E
S
Site 17
S246
S
L
V
V
D
R
E
S
S
H
D
G
C
Q
D
Site 18
S247
L
V
V
D
R
E
S
S
H
D
G
C
Q
D
A
Site 19
S280
V
V
S
A
G
P
L
S
S
E
K
A
E
M
N
Site 20
S281
V
S
A
G
P
L
S
S
E
K
A
E
M
N
I
Site 21
S308
E
K
K
Q
Q
F
R
S
L
K
E
K
C
F
V
Site 22
Y329
L
A
K
Q
Q
N
K
Y
K
Y
E
E
C
K
D
Site 23
Y331
K
Q
Q
N
K
Y
K
Y
E
E
C
K
D
L
I
Site 24
S340
E
C
K
D
L
I
K
S
M
L
R
N
E
R
Q
Site 25
S434
Q
H
L
V
Q
K
L
S
P
E
N
D
N
D
D
Site 26
S456
V
A
E
K
V
Q
K
S
S
S
P
R
E
M
Q
Site 27
S457
A
E
K
V
Q
K
S
S
S
P
R
E
M
Q
K
Site 28
S458
E
K
V
Q
K
S
S
S
P
R
E
M
Q
K
A
Site 29
S474
E
K
E
V
P
E
D
S
L
E
E
C
A
I
T
Site 30
Y489
C
S
N
S
H
G
P
Y
D
S
N
Q
P
H
R
Site 31
S491
N
S
H
G
P
Y
D
S
N
Q
P
H
R
K
T
Site 32
T498
S
N
Q
P
H
R
K
T
K
I
T
F
E
E
D
Site 33
T501
P
H
R
K
T
K
I
T
F
E
E
D
K
V
D
Site 34
S509
F
E
E
D
K
V
D
S
T
L
I
G
S
S
S
Site 35
T510
E
E
D
K
V
D
S
T
L
I
G
S
S
S
H
Site 36
S516
S
T
L
I
G
S
S
S
H
V
E
W
E
D
A
Site 37
S544
E
E
E
K
G
P
V
S
P
R
N
L
Q
E
S
Site 38
S551
S
P
R
N
L
Q
E
S
E
E
E
E
V
P
Q
Site 39
S560
E
E
E
V
P
Q
E
S
W
D
E
G
Y
S
T
Site 40
Y565
Q
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
Site 41
S566
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
Site 42
T567
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
R
Site 43
S569
D
E
G
Y
S
T
L
S
I
P
P
E
R
T
S
Site 44
T575
L
S
I
P
P
E
R
T
S
V
G
S
S
E
K
Site 45
S576
S
I
P
P
E
R
T
S
V
G
S
S
E
K
G
Site 46
S579
P
E
R
T
S
V
G
S
S
E
K
G
G
P
R
Site 47
S580
E
R
T
S
V
G
S
S
E
K
G
G
P
R
G
Site 48
S590
G
G
P
R
G
N
R
S
Q
A
Q
Q
G
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation