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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RBMY1B
Full Name:
RNA-binding motif protein, Y chromosome, family 1 member B
Alias:
Type:
Mass (Da):
55835
Number AA:
496
UniProt ID:
A6NDE4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
I
G
G
L
N
R
E
T
N
E
K
M
L
K
A
Site 2
T44
V
L
L
I
K
D
R
T
S
K
S
R
G
F
A
Site 3
S45
L
L
I
K
D
R
T
S
K
S
R
G
F
A
F
Site 4
S47
I
K
D
R
T
S
K
S
R
G
F
A
F
I
T
Site 5
T54
S
R
G
F
A
F
I
T
F
E
N
P
A
D
A
Site 6
S72
A
K
D
M
N
G
K
S
L
H
G
K
A
I
K
Site 7
S87
V
E
Q
A
K
K
P
S
F
Q
S
G
G
R
R
Site 8
S90
A
K
K
P
S
F
Q
S
G
G
R
R
R
P
P
Site 9
S99
G
R
R
R
P
P
A
S
S
R
N
R
S
P
S
Site 10
S100
R
R
R
P
P
A
S
S
R
N
R
S
P
S
G
Site 11
S104
P
A
S
S
R
N
R
S
P
S
G
S
L
R
S
Site 12
S106
S
S
R
N
R
S
P
S
G
S
L
R
S
A
R
Site 13
S108
R
N
R
S
P
S
G
S
L
R
S
A
R
G
S
Site 14
S111
S
P
S
G
S
L
R
S
A
R
G
S
R
G
G
Site 15
S115
S
L
R
S
A
R
G
S
R
G
G
T
R
G
W
Site 16
T119
A
R
G
S
R
G
G
T
R
G
W
L
P
S
Q
Site 17
S125
G
T
R
G
W
L
P
S
Q
E
G
H
L
D
D
Site 18
Y135
G
H
L
D
D
G
G
Y
T
P
D
L
K
M
S
Site 19
T136
H
L
D
D
G
G
Y
T
P
D
L
K
M
S
Y
Site 20
S142
Y
T
P
D
L
K
M
S
Y
S
R
G
L
I
P
Site 21
S144
P
D
L
K
M
S
Y
S
R
G
L
I
P
V
K
Site 22
S155
I
P
V
K
R
G
P
S
S
R
S
G
G
P
P
Site 23
S156
P
V
K
R
G
P
S
S
R
S
G
G
P
P
P
Site 24
S158
K
R
G
P
S
S
R
S
G
G
P
P
P
K
K
Site 25
S166
G
G
P
P
P
K
K
S
A
P
S
A
V
A
R
Site 26
S174
A
P
S
A
V
A
R
S
N
S
W
M
G
S
Q
Site 27
S176
S
A
V
A
R
S
N
S
W
M
G
S
Q
G
P
Site 28
S180
R
S
N
S
W
M
G
S
Q
G
P
M
S
Q
R
Site 29
S185
M
G
S
Q
G
P
M
S
Q
R
R
E
N
Y
G
Site 30
Y191
M
S
Q
R
R
E
N
Y
G
V
P
P
R
R
A
Site 31
T199
G
V
P
P
R
R
A
T
I
S
S
W
R
N
D
Site 32
S201
P
P
R
R
A
T
I
S
S
W
R
N
D
R
M
Site 33
S202
P
R
R
A
T
I
S
S
W
R
N
D
R
M
S
Site 34
T210
W
R
N
D
R
M
S
T
R
H
D
G
Y
A
T
Site 35
Y215
M
S
T
R
H
D
G
Y
A
T
N
D
G
N
H
Site 36
T228
N
H
P
S
C
Q
E
T
R
D
Y
A
P
P
S
Site 37
Y231
S
C
Q
E
T
R
D
Y
A
P
P
S
R
G
Y
Site 38
S235
T
R
D
Y
A
P
P
S
R
G
Y
A
Y
R
D
Site 39
Y238
Y
A
P
P
S
R
G
Y
A
Y
R
D
N
G
H
Site 40
Y240
P
P
S
R
G
Y
A
Y
R
D
N
G
H
S
N
Site 41
S246
A
Y
R
D
N
G
H
S
N
R
D
E
H
S
S
Site 42
S252
H
S
N
R
D
E
H
S
S
R
G
Y
R
N
H
Site 43
S253
S
N
R
D
E
H
S
S
R
G
Y
R
N
H
R
Site 44
Y256
D
E
H
S
S
R
G
Y
R
N
H
R
S
S
R
Site 45
S261
R
G
Y
R
N
H
R
S
S
R
E
T
R
D
Y
Site 46
S262
G
Y
R
N
H
R
S
S
R
E
T
R
D
Y
A
Site 47
T265
N
H
R
S
S
R
E
T
R
D
Y
A
P
P
S
Site 48
Y268
S
S
R
E
T
R
D
Y
A
P
P
S
R
G
H
Site 49
S272
T
R
D
Y
A
P
P
S
R
G
H
A
Y
R
D
Site 50
Y277
P
P
S
R
G
H
A
Y
R
D
Y
G
H
S
R
Site 51
Y280
R
G
H
A
Y
R
D
Y
G
H
S
R
R
D
E
Site 52
S283
A
Y
R
D
Y
G
H
S
R
R
D
E
S
Y
S
Site 53
S288
G
H
S
R
R
D
E
S
Y
S
R
G
Y
R
N
Site 54
Y289
H
S
R
R
D
E
S
Y
S
R
G
Y
R
N
R
Site 55
S290
S
R
R
D
E
S
Y
S
R
G
Y
R
N
R
R
Site 56
Y293
D
E
S
Y
S
R
G
Y
R
N
R
R
S
S
R
Site 57
S298
R
G
Y
R
N
R
R
S
S
R
E
T
R
E
Y
Site 58
S299
G
Y
R
N
R
R
S
S
R
E
T
R
E
Y
A
Site 59
T302
N
R
R
S
S
R
E
T
R
E
Y
A
P
P
S
Site 60
Y305
S
S
R
E
T
R
E
Y
A
P
P
S
R
G
H
Site 61
S309
T
R
E
Y
A
P
P
S
R
G
H
G
Y
R
D
Site 62
Y314
P
P
S
R
G
H
G
Y
R
D
Y
G
H
S
R
Site 63
Y317
R
G
H
G
Y
R
D
Y
G
H
S
R
R
H
E
Site 64
S320
G
Y
R
D
Y
G
H
S
R
R
H
E
S
Y
S
Site 65
S325
G
H
S
R
R
H
E
S
Y
S
R
G
Y
R
N
Site 66
Y326
H
S
R
R
H
E
S
Y
S
R
G
Y
R
N
H
Site 67
S327
S
R
R
H
E
S
Y
S
R
G
Y
R
N
H
P
Site 68
Y330
H
E
S
Y
S
R
G
Y
R
N
H
P
S
S
R
Site 69
S335
R
G
Y
R
N
H
P
S
S
R
E
T
R
D
Y
Site 70
S336
G
Y
R
N
H
P
S
S
R
E
T
R
D
Y
A
Site 71
T339
N
H
P
S
S
R
E
T
R
D
Y
A
P
P
H
Site 72
Y342
S
S
R
E
T
R
D
Y
A
P
P
H
R
D
Y
Site 73
Y349
Y
A
P
P
H
R
D
Y
A
Y
R
D
Y
G
H
Site 74
Y351
P
P
H
R
D
Y
A
Y
R
D
Y
G
H
S
S
Site 75
Y354
R
D
Y
A
Y
R
D
Y
G
H
S
S
W
D
E
Site 76
S357
A
Y
R
D
Y
G
H
S
S
W
D
E
H
S
S
Site 77
S358
Y
R
D
Y
G
H
S
S
W
D
E
H
S
S
R
Site 78
S364
S
S
W
D
E
H
S
S
R
G
Y
S
Y
H
D
Site 79
Y367
D
E
H
S
S
R
G
Y
S
Y
H
D
G
Y
G
Site 80
S368
E
H
S
S
R
G
Y
S
Y
H
D
G
Y
G
E
Site 81
Y369
H
S
S
R
G
Y
S
Y
H
D
G
Y
G
E
A
Site 82
Y373
G
Y
S
Y
H
D
G
Y
G
E
A
L
G
R
D
Site 83
S382
E
A
L
G
R
D
H
S
E
H
L
S
G
S
S
Site 84
S386
R
D
H
S
E
H
L
S
G
S
S
Y
R
D
A
Site 85
S389
S
E
H
L
S
G
S
S
Y
R
D
A
L
Q
R
Site 86
Y390
E
H
L
S
G
S
S
Y
R
D
A
L
Q
R
Y
Site 87
Y397
Y
R
D
A
L
Q
R
Y
G
T
S
H
G
A
P
Site 88
T399
D
A
L
Q
R
Y
G
T
S
H
G
A
P
P
A
Site 89
S412
P
A
R
G
P
R
M
S
Y
G
G
S
T
C
H
Site 90
Y413
A
R
G
P
R
M
S
Y
G
G
S
T
C
H
A
Site 91
S416
P
R
M
S
Y
G
G
S
T
C
H
A
Y
S
N
Site 92
Y421
G
G
S
T
C
H
A
Y
S
N
T
R
D
R
Y
Site 93
S422
G
S
T
C
H
A
Y
S
N
T
R
D
R
Y
G
Site 94
Y428
Y
S
N
T
R
D
R
Y
G
R
S
W
E
S
Y
Site 95
S431
T
R
D
R
Y
G
R
S
W
E
S
Y
S
S
C
Site 96
S434
R
Y
G
R
S
W
E
S
Y
S
S
C
G
D
F
Site 97
Y435
Y
G
R
S
W
E
S
Y
S
S
C
G
D
F
H
Site 98
S437
R
S
W
E
S
Y
S
S
C
G
D
F
H
Y
C
Site 99
S459
K
D
Q
R
N
P
P
S
L
G
R
V
L
P
D
Site 100
Y471
L
P
D
P
R
E
A
Y
G
S
S
S
Y
V
A
Site 101
S473
D
P
R
E
A
Y
G
S
S
S
Y
V
A
S
I
Site 102
S475
R
E
A
Y
G
S
S
S
Y
V
A
S
I
V
D
Site 103
Y476
E
A
Y
G
S
S
S
Y
V
A
S
I
V
D
G
Site 104
S479
G
S
S
S
Y
V
A
S
I
V
D
G
G
E
S
Site 105
S488
V
D
G
G
E
S
R
S
E
K
G
D
S
S
R
Site 106
S493
S
R
S
E
K
G
D
S
S
R
Y
_
_
_
_
Site 107
Y496
E
K
G
D
S
S
R
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation