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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM35B
Full Name:
Protein FAM35B
Alias:
Type:
Mass (Da):
93675
Number AA:
834
UniProt ID:
A6NDK8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
P
V
A
P
L
K
M
T
V
S
E
D
T
A
S
Site 2
S28
T
V
S
E
D
T
A
S
L
M
S
V
A
D
P
Site 3
Y43
W
K
K
I
Q
L
L
Y
S
Q
H
S
L
Y
L
Site 4
S44
K
K
I
Q
L
L
Y
S
Q
H
S
L
Y
L
K
Site 5
S47
Q
L
L
Y
S
Q
H
S
L
Y
L
K
D
E
K
Site 6
Y49
L
Y
S
Q
H
S
L
Y
L
K
D
E
K
Q
H
Site 7
Y62
Q
H
K
N
L
E
N
Y
E
V
P
D
S
I
G
Site 8
S67
E
N
Y
E
V
P
D
S
I
G
S
P
D
L
C
Site 9
S70
E
V
P
D
S
I
G
S
P
D
L
C
G
H
F
Site 10
S95
V
K
D
D
F
V
R
S
V
S
E
T
Q
N
I
Site 11
S97
D
D
F
V
R
S
V
S
E
T
Q
N
I
E
S
Site 12
T99
F
V
R
S
V
S
E
T
Q
N
I
E
S
Q
K
Site 13
S104
S
E
T
Q
N
I
E
S
Q
K
I
H
S
S
R
Site 14
S109
I
E
S
Q
K
I
H
S
S
R
L
S
G
I
T
Site 15
S110
E
S
Q
K
I
H
S
S
R
L
S
G
I
T
S
Site 16
S113
K
I
H
S
S
R
L
S
G
I
T
S
S
N
M
Site 17
T116
S
S
R
L
S
G
I
T
S
S
N
M
Q
I
C
Site 18
S117
S
R
L
S
G
I
T
S
S
N
M
Q
I
C
G
Site 19
T128
Q
I
C
G
F
K
S
T
V
P
H
L
T
E
E
Site 20
Y138
H
L
T
E
E
E
K
Y
Q
K
L
L
S
E
N
Site 21
Y203
R
E
C
V
P
T
E
Y
H
E
I
Q
N
Q
R
Site 22
S215
N
Q
R
L
G
L
F
S
S
N
S
V
D
K
S
Site 23
S216
Q
R
L
G
L
F
S
S
N
S
V
D
K
S
R
Site 24
S218
L
G
L
F
S
S
N
S
V
D
K
S
R
S
E
Site 25
S222
S
S
N
S
V
D
K
S
R
S
E
A
A
V
K
Site 26
S224
N
S
V
D
K
S
R
S
E
A
A
V
K
K
V
Site 27
S232
E
A
A
V
K
K
V
S
D
L
K
I
S
T
D
Site 28
T238
V
S
D
L
K
I
S
T
D
K
E
F
L
S
I
Site 29
S244
S
T
D
K
E
F
L
S
I
I
T
S
S
Q
V
Site 30
S263
Q
K
K
D
K
R
R
S
P
V
N
K
G
N
V
Site 31
T274
K
G
N
V
N
M
E
T
E
P
K
A
S
Y
G
Site 32
S279
M
E
T
E
P
K
A
S
Y
G
E
I
R
I
P
Site 33
T297
S
I
Q
L
D
G
F
T
E
A
Y
E
S
G
Q
Site 34
Y300
L
D
G
F
T
E
A
Y
E
S
G
Q
N
Q
A
Site 35
S309
S
G
Q
N
Q
A
Y
S
L
E
L
F
S
P
V
Site 36
S314
A
Y
S
L
E
L
F
S
P
V
C
P
K
T
E
Site 37
T320
F
S
P
V
C
P
K
T
E
N
S
R
I
H
I
Site 38
S329
N
S
R
I
H
I
N
S
D
K
G
L
E
E
H
Site 39
S339
G
L
E
E
H
T
G
S
Q
E
L
F
S
S
E
Site 40
S344
T
G
S
Q
E
L
F
S
S
E
D
E
L
P
P
Site 41
S345
G
S
Q
E
L
F
S
S
E
D
E
L
P
P
N
Site 42
S366
C
S
S
G
I
L
C
S
Q
L
N
T
F
H
K
Site 43
S379
H
K
S
A
I
K
R
S
C
T
S
E
D
K
V
Site 44
T381
S
A
I
K
R
S
C
T
S
E
D
K
V
A
Q
Site 45
S389
S
E
D
K
V
A
Q
S
E
A
L
S
R
V
L
Site 46
S406
A
K
K
M
K
L
I
S
N
G
G
D
S
A
V
Site 47
S421
E
M
D
R
R
N
V
S
E
F
K
S
I
K
K
Site 48
S425
R
N
V
S
E
F
K
S
I
K
K
S
L
I
K
Site 49
S429
E
F
K
S
I
K
K
S
L
I
K
N
C
D
S
Site 50
Y441
C
D
S
K
S
Q
K
Y
N
C
L
V
M
V
L
Site 51
S464
N
I
K
F
G
P
N
S
G
S
K
V
P
L
A
Site 52
S466
K
F
G
P
N
S
G
S
K
V
P
L
A
T
V
Site 53
T472
G
S
K
V
P
L
A
T
V
T
V
S
D
Q
S
Site 54
T474
K
V
P
L
A
T
V
T
V
S
D
Q
S
E
T
Site 55
S476
P
L
A
T
V
T
V
S
D
Q
S
E
T
K
K
Site 56
T520
E
D
Q
W
I
G
E
T
V
L
Q
S
T
F
S
Site 57
T525
G
E
T
V
L
Q
S
T
F
S
S
Q
L
L
N
Site 58
S535
S
Q
L
L
N
L
G
S
Y
S
S
I
Q
P
E
Site 59
S538
L
N
L
G
S
Y
S
S
I
Q
P
E
E
Y
S
Site 60
Y544
S
S
I
Q
P
E
E
Y
S
S
V
V
S
D
V
Site 61
S545
S
I
Q
P
E
E
Y
S
S
V
V
S
D
V
V
Site 62
Y559
V
L
Q
D
L
L
A
Y
V
S
S
K
H
S
Y
Site 63
S561
Q
D
L
L
A
Y
V
S
S
K
H
S
Y
L
R
Site 64
S562
D
L
L
A
Y
V
S
S
K
H
S
Y
L
R
D
Site 65
S565
A
Y
V
S
S
K
H
S
Y
L
R
D
L
P
P
Site 66
Y566
Y
V
S
S
K
H
S
Y
L
R
D
L
P
P
R
Site 67
S580
R
Q
P
Q
R
V
N
S
I
D
F
V
E
L
E
Site 68
Y612
L
I
M
K
K
A
V
Y
S
Y
R
G
Q
K
Q
Site 69
S613
I
M
K
K
A
V
Y
S
Y
R
G
Q
K
Q
K
Site 70
T625
K
Q
K
K
V
M
L
T
V
E
Q
A
Q
D
Q
Site 71
Y634
E
Q
A
Q
D
Q
H
Y
A
L
V
L
W
G
P
Site 72
Y646
W
G
P
G
A
A
W
Y
P
Q
L
Q
R
K
K
Site 73
S681
K
I
S
L
N
A
H
S
S
L
K
S
I
F
S
Site 74
S685
N
A
H
S
S
L
K
S
I
F
S
S
L
P
N
Site 75
Y713
E
T
D
E
N
R
I
Y
K
Q
C
F
S
C
L
Site 76
Y728
P
F
T
M
K
K
I
Y
Y
R
P
A
L
M
T
Site 77
T735
Y
Y
R
P
A
L
M
T
A
V
D
G
R
H
N
Site 78
Y744
V
D
G
R
H
N
V
Y
I
H
V
E
S
K
L
Site 79
S809
L
F
V
L
D
E
N
S
Y
P
L
Q
Q
D
F
Site 80
Y810
F
V
L
D
E
N
S
Y
P
L
Q
Q
D
F
S
Site 81
S817
Y
P
L
Q
Q
D
F
S
L
L
D
F
Y
P
D
Site 82
Y822
D
F
S
L
L
D
F
Y
P
D
M
V
K
H
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation