KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KIAA1875
Full Name:
WD repeat-containing protein KIAA1875
Alias:
Type:
Mass (Da):
180307
Number AA:
1622
UniProt ID:
A6NE52
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
E
V
W
E
A
E
G
Y
N
L
V
L
D
S
D
Site 2
S17
G
Y
N
L
V
L
D
S
D
L
Y
D
A
D
G
Site 3
Y20
L
V
L
D
S
D
L
Y
D
A
D
G
Y
D
V
Site 4
Y25
D
L
Y
D
A
D
G
Y
D
V
P
D
P
G
L
Site 5
T34
V
P
D
P
G
L
L
T
E
K
N
E
L
T
F
Site 6
T40
L
T
E
K
N
E
L
T
F
T
E
P
S
Q
V
Site 7
T42
E
K
N
E
L
T
F
T
E
P
S
Q
V
L
P
Site 8
T52
S
Q
V
L
P
F
L
T
S
S
Q
Q
W
Q
S
Site 9
S53
Q
V
L
P
F
L
T
S
S
Q
Q
W
Q
S
L
Site 10
S54
V
L
P
F
L
T
S
S
Q
Q
W
Q
S
L
T
Site 11
S59
T
S
S
Q
Q
W
Q
S
L
T
P
R
A
R
A
Site 12
T61
S
Q
Q
W
Q
S
L
T
P
R
A
R
A
R
R
Site 13
T95
E
L
R
A
A
R
L
T
H
G
L
E
P
L
R
Site 14
S237
R
R
L
V
L
R
G
S
A
L
H
P
P
P
S
Site 15
S244
S
A
L
H
P
P
P
S
P
T
G
R
L
M
R
Site 16
T293
V
R
R
D
L
H
K
T
T
I
S
D
L
A
Y
Site 17
S296
D
L
H
K
T
T
I
S
D
L
A
Y
C
E
E
Site 18
T309
E
E
V
E
A
M
V
T
A
S
R
D
S
T
V
Site 19
S314
M
V
T
A
S
R
D
S
T
V
K
V
W
E
A
Site 20
T315
V
T
A
S
R
D
S
T
V
K
V
W
E
A
D
Site 21
S350
P
N
T
T
L
V
L
S
A
S
Q
D
G
T
L
Site 22
S352
T
T
L
V
L
S
A
S
Q
D
G
T
L
R
T
Site 23
T356
L
S
A
S
Q
D
G
T
L
R
T
W
D
L
Q
Site 24
S382
F
W
G
Q
D
K
L
S
R
R
V
G
R
L
L
Site 25
Y415
L
W
R
V
R
E
L
Y
S
P
L
A
Q
L
P
Site 26
S416
W
R
V
R
E
L
Y
S
P
L
A
Q
L
P
A
Site 27
Y530
Q
P
C
C
L
H
L
Y
S
H
L
T
D
L
E
Site 28
S541
T
D
L
E
G
A
F
S
S
W
E
I
V
R
Q
Site 29
S542
D
L
E
G
A
F
S
S
W
E
I
V
R
Q
H
Site 30
Y568
A
W
K
N
K
N
R
Y
L
P
V
V
G
H
T
Site 31
S580
G
H
T
D
G
T
L
S
V
L
E
W
L
S
S
Site 32
S587
S
V
L
E
W
L
S
S
K
T
V
F
Q
T
E
Site 33
T589
L
E
W
L
S
S
K
T
V
F
Q
T
E
A
H
Site 34
T593
S
S
K
T
V
F
Q
T
E
A
H
S
P
G
P
Site 35
S614
T
W
N
S
I
V
S
S
G
G
D
L
T
V
K
Site 36
Y628
K
M
W
R
V
F
P
Y
A
E
E
S
L
S
L
Site 37
S634
P
Y
A
E
E
S
L
S
L
L
R
T
F
S
C
Site 38
T656
C
A
L
G
R
R
V
T
A
G
F
E
D
P
D
Site 39
S664
A
G
F
E
D
P
D
S
A
T
Y
G
L
V
Q
Site 40
S677
V
Q
F
G
L
G
D
S
P
R
L
D
H
R
P
Site 41
T689
H
R
P
Q
D
D
P
T
D
H
I
T
G
L
C
Site 42
T717
D
C
T
V
R
I
W
T
A
E
N
R
L
L
R
Site 43
T763
S
H
R
L
Y
L
P
T
S
Y
L
V
K
K
M
Site 44
Y765
R
L
Y
L
P
T
S
Y
L
V
K
K
M
C
R
Site 45
S787
D
P
P
L
P
L
M
S
Q
E
S
L
T
S
A
Site 46
S790
L
P
L
M
S
Q
E
S
L
T
S
A
Q
L
Q
Site 47
T800
S
A
Q
L
Q
R
L
T
N
L
H
G
A
A
S
Site 48
S813
A
S
L
S
E
A
L
S
L
I
H
R
R
R
A
Site 49
T821
L
I
H
R
R
R
A
T
S
Q
H
L
V
P
K
Site 50
S822
I
H
R
R
R
A
T
S
Q
H
L
V
P
K
E
Site 51
S858
P
A
A
Q
P
P
P
S
W
Q
Q
R
Q
E
G
Site 52
Y869
R
Q
E
G
F
D
N
Y
L
R
L
I
Y
G
S
Site 53
S883
S
G
L
L
G
M
Q
S
G
R
G
S
Q
Q
W
Site 54
S887
G
M
Q
S
G
R
G
S
Q
Q
W
S
A
G
T
Site 55
S891
G
R
G
S
Q
Q
W
S
A
G
T
L
R
V
E
Site 56
T901
T
L
R
V
E
R
E
T
R
D
V
C
A
V
P
Site 57
S943
G
A
L
G
Q
H
F
S
Q
S
P
R
V
T
V
Site 58
S945
L
G
Q
H
F
S
Q
S
P
R
V
T
V
P
I
Site 59
T949
F
S
Q
S
P
R
V
T
V
P
I
P
P
T
H
Site 60
T955
V
T
V
P
I
P
P
T
H
R
R
V
H
S
K
Site 61
S961
P
T
H
R
R
V
H
S
K
A
S
Q
L
L
A
Site 62
S970
A
S
Q
L
L
A
R
S
S
L
S
H
Y
L
G
Site 63
T993
L
E
Q
L
R
G
R
T
T
M
A
L
D
L
P
Site 64
T994
E
Q
L
R
G
R
T
T
M
A
L
D
L
P
S
Site 65
S1021
R
W
D
K
E
P
L
S
S
L
R
G
F
F
P
Site 66
S1022
W
D
K
E
P
L
S
S
L
R
G
F
F
P
A
Site 67
T1030
L
R
G
F
F
P
A
T
V
Q
P
H
K
H
C
Site 68
S1065
L
N
A
E
P
G
A
S
Q
D
A
L
W
L
W
Site 69
S1119
E
L
D
W
A
L
A
S
L
S
P
H
S
N
Q
Site 70
S1121
D
W
A
L
A
S
L
S
P
H
S
N
Q
Q
L
Site 71
S1124
L
A
S
L
S
P
H
S
N
Q
Q
L
D
S
W
Site 72
S1130
H
S
N
Q
Q
L
D
S
W
E
L
E
D
Q
S
Site 73
S1137
S
W
E
L
E
D
Q
S
A
V
D
W
T
Q
E
Site 74
T1142
D
Q
S
A
V
D
W
T
Q
E
P
R
R
R
S
Site 75
S1149
T
Q
E
P
R
R
R
S
C
K
V
A
R
T
H
Site 76
Y1172
S
L
L
L
D
E
H
Y
G
H
L
P
K
F
L
Site 77
S1196
K
K
L
F
P
I
F
S
L
Q
A
Y
P
E
A
Site 78
S1240
L
R
L
L
P
N
M
S
S
D
L
Q
G
Q
L
Site 79
S1262
L
N
L
D
Q
P
P
S
L
Q
D
Q
T
Q
K
Site 80
T1267
P
P
S
L
Q
D
Q
T
Q
K
K
F
V
I
L
Site 81
Y1299
E
L
M
S
Y
F
L
Y
S
P
V
H
C
R
P
Site 82
S1300
L
M
S
Y
F
L
Y
S
P
V
H
C
R
P
E
Site 83
S1339
V
Q
G
P
D
L
D
S
K
A
G
L
R
T
C
Site 84
T1361
M
I
Q
E
L
Q
E
T
P
S
Q
T
S
V
V
Site 85
S1363
Q
E
L
Q
E
T
P
S
Q
T
S
V
V
S
G
Site 86
T1365
L
Q
E
T
P
S
Q
T
S
V
V
S
G
A
P
Site 87
S1366
Q
E
T
P
S
Q
T
S
V
V
S
G
A
P
T
Site 88
S1369
P
S
Q
T
S
V
V
S
G
A
P
T
R
A
S
Site 89
S1376
S
G
A
P
T
R
A
S
V
I
P
S
G
T
S
Site 90
S1380
T
R
A
S
V
I
P
S
G
T
S
W
S
A
S
Site 91
S1385
I
P
S
G
T
S
W
S
A
S
G
I
F
G
R
Site 92
S1387
S
G
T
S
W
S
A
S
G
I
F
G
R
L
S
Site 93
S1411
V
S
P
A
E
P
H
S
L
A
P
E
L
Q
A
Site 94
S1427
R
M
L
A
P
K
R
S
W
G
T
P
Q
L
R
Site 95
T1430
A
P
K
R
S
W
G
T
P
Q
L
R
L
R
V
Site 96
T1471
E
P
P
P
L
E
E
T
D
W
S
H
S
Q
L
Site 97
S1474
P
L
E
E
T
D
W
S
H
S
Q
L
L
D
L
Site 98
S1476
E
E
T
D
W
S
H
S
Q
L
L
D
L
G
P
Site 99
S1500
Q
L
R
A
Q
Q
R
S
S
L
Q
E
K
A
A
Site 100
S1501
L
R
A
Q
Q
R
S
S
L
Q
E
K
A
A
H
Site 101
T1516
P
H
P
P
E
P
Y
T
V
A
P
V
P
D
M
Site 102
Y1533
P
P
P
R
E
H
W
Y
H
P
I
L
R
L
Q
Site 103
S1547
Q
E
A
K
P
Q
R
S
A
R
S
A
M
R
L
Site 104
S1550
K
P
Q
R
S
A
R
S
A
M
R
L
R
G
P
Site 105
S1560
R
L
R
G
P
M
R
S
R
L
C
A
G
R
T
Site 106
T1567
S
R
L
C
A
G
R
T
L
D
G
P
I
R
T
Site 107
Y1610
L
Q
P
A
L
Q
R
Y
F
L
P
A
D
A
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation