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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD56
Full Name:
Ankyrin repeat domain-containing protein 56
Alias:
Ankyrin repeat domain 56; ANR56
Type:
Mass (Da):
85724
Number AA:
793
UniProt ID:
A6NEL2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
R
E
L
S
Q
E
A
L
L
D
F
Site 2
S32
A
L
L
S
H
F
K
S
F
L
R
D
P
D
A
Site 3
S40
F
L
R
D
P
D
A
S
P
S
Q
H
Q
H
R
Site 4
S42
R
D
P
D
A
S
P
S
Q
H
Q
H
R
R
E
Site 5
T68
V
R
Q
D
P
D
G
T
K
Y
V
V
L
K
R
Site 6
Y70
Q
D
P
D
G
T
K
Y
V
V
L
K
R
R
Y
Site 7
Y77
Y
V
V
L
K
R
R
Y
R
D
L
L
G
E
E
Site 8
S106
A
G
G
A
A
P
C
S
P
R
G
A
R
R
G
Site 9
S151
A
C
N
G
L
P
G
S
D
S
R
R
A
P
G
Site 10
S153
N
G
L
P
G
S
D
S
R
R
A
P
G
K
G
Site 11
S163
A
P
G
K
G
G
G
S
K
G
S
P
G
Q
R
Site 12
S166
K
G
G
G
S
K
G
S
P
G
Q
R
P
P
V
Site 13
S186
A
G
A
Q
A
R
A
S
C
A
A
A
K
T
Q
Site 14
S218
E
L
G
A
L
P
H
S
A
T
A
E
E
K
P
Site 15
T220
G
A
L
P
H
S
A
T
A
E
E
K
P
A
R
Site 16
S238
A
Q
D
D
R
G
A
S
R
E
R
E
E
G
A
Site 17
T262
V
A
H
S
P
P
A
T
V
E
A
A
T
S
R
Site 18
T267
P
A
T
V
E
A
A
T
S
R
A
S
P
P
A
Site 19
S271
E
A
A
T
S
R
A
S
P
P
A
L
L
P
G
Site 20
T290
G
D
R
P
E
L
L
T
P
S
S
L
H
Y
S
Site 21
S292
R
P
E
L
L
T
P
S
S
L
H
Y
S
T
L
Site 22
S293
P
E
L
L
T
P
S
S
L
H
Y
S
T
L
Q
Site 23
S297
T
P
S
S
L
H
Y
S
T
L
Q
Q
Q
Q
Q
Site 24
S329
Q
G
P
I
R
A
W
S
V
L
P
D
N
F
L
Site 25
S344
Q
L
P
L
E
P
G
S
T
E
P
N
S
E
P
Site 26
T345
L
P
L
E
P
G
S
T
E
P
N
S
E
P
P
Site 27
S349
P
G
S
T
E
P
N
S
E
P
P
D
P
C
L
Site 28
S357
E
P
P
D
P
C
L
S
S
H
S
L
F
P
V
Site 29
S372
V
P
D
E
S
W
E
S
W
A
G
N
P
S
L
Site 30
S378
E
S
W
A
G
N
P
S
L
T
V
F
R
S
I
Site 31
T380
W
A
G
N
P
S
L
T
V
F
R
S
I
R
C
Site 32
S390
R
S
I
R
C
Q
L
S
L
Q
D
L
D
D
F
Site 33
S402
D
D
F
V
D
Q
E
S
D
G
S
E
E
S
S
Site 34
S405
V
D
Q
E
S
D
G
S
E
E
S
S
S
G
P
Site 35
S409
S
D
G
S
E
E
S
S
S
G
P
K
D
S
P
Site 36
S410
D
G
S
E
E
S
S
S
G
P
K
D
S
P
G
Site 37
S415
S
S
S
G
P
K
D
S
P
G
A
S
E
E
G
Site 38
S419
P
K
D
S
P
G
A
S
E
E
G
L
Q
V
V
Site 39
T429
G
L
Q
V
V
L
G
T
P
D
R
G
K
L
R
Site 40
S443
R
N
P
A
G
G
L
S
V
S
R
K
E
G
S
Site 41
S445
P
A
G
G
L
S
V
S
R
K
E
G
S
P
S
Site 42
S450
S
V
S
R
K
E
G
S
P
S
R
S
P
Q
G
Site 43
S452
S
R
K
E
G
S
P
S
R
S
P
Q
G
L
R
Site 44
S454
K
E
G
S
P
S
R
S
P
Q
G
L
R
N
R
Site 45
S467
N
R
G
D
G
H
I
S
Q
Q
V
P
A
G
A
Site 46
S495
P
V
P
K
L
R
R
S
L
R
R
S
S
L
A
Site 47
S499
L
R
R
S
L
R
R
S
S
L
A
G
R
A
K
Site 48
S500
R
R
S
L
R
R
S
S
L
A
G
R
A
K
L
Site 49
S508
L
A
G
R
A
K
L
S
S
S
D
E
E
Y
L
Site 50
S509
A
G
R
A
K
L
S
S
S
D
E
E
Y
L
D
Site 51
S510
G
R
A
K
L
S
S
S
D
E
E
Y
L
D
E
Site 52
Y514
L
S
S
S
D
E
E
Y
L
D
E
G
L
L
K
Site 53
S523
D
E
G
L
L
K
R
S
R
R
P
P
R
S
R
Site 54
S529
R
S
R
R
P
P
R
S
R
K
P
S
K
A
G
Site 55
S533
P
P
R
S
R
K
P
S
K
A
G
T
A
P
S
Site 56
T537
R
K
P
S
K
A
G
T
A
P
S
P
R
V
D
Site 57
S540
S
K
A
G
T
A
P
S
P
R
V
D
A
G
L
Site 58
S566
A
E
R
G
W
R
H
S
L
W
V
P
S
G
E
Site 59
S571
R
H
S
L
W
V
P
S
G
E
G
S
A
A
L
Site 60
S575
W
V
P
S
G
E
G
S
A
A
L
A
P
H
R
Site 61
T583
A
A
L
A
P
H
R
T
S
E
H
K
S
S
L
Site 62
S584
A
L
A
P
H
R
T
S
E
H
K
S
S
L
V
Site 63
S588
H
R
T
S
E
H
K
S
S
L
V
P
L
D
A
Site 64
S589
R
T
S
E
H
K
S
S
L
V
P
L
D
A
R
Site 65
T630
A
L
H
K
D
F
L
T
G
Y
T
A
L
H
W
Site 66
S652
R
A
L
Q
D
L
V
S
G
A
K
K
A
G
I
Site 67
S668
L
D
V
N
V
R
S
S
C
G
Y
T
P
L
H
Site 68
Y671
N
V
R
S
S
C
G
Y
T
P
L
H
L
A
A
Site 69
S695
L
L
V
Q
R
L
A
S
R
V
N
V
R
D
S
Site 70
S702
S
R
V
N
V
R
D
S
S
G
K
K
P
W
Q
Site 71
S703
R
V
N
V
R
D
S
S
G
K
K
P
W
Q
Y
Site 72
Y710
S
G
K
K
P
W
Q
Y
L
T
S
N
T
S
G
Site 73
T712
K
K
P
W
Q
Y
L
T
S
N
T
S
G
E
I
Site 74
S740
P
V
Y
P
L
V
G
S
S
S
P
T
R
K
A
Site 75
S742
Y
P
L
V
G
S
S
S
P
T
R
K
A
K
S
Site 76
T744
L
V
G
S
S
S
P
T
R
K
A
K
S
K
E
Site 77
S749
S
P
T
R
K
A
K
S
K
E
I
S
R
S
V
Site 78
S753
K
A
K
S
K
E
I
S
R
S
V
T
R
K
T
Site 79
S755
K
S
K
E
I
S
R
S
V
T
R
K
T
S
F
Site 80
T757
K
E
I
S
R
S
V
T
R
K
T
S
F
A
A
Site 81
T760
S
R
S
V
T
R
K
T
S
F
A
A
L
L
K
Site 82
S761
R
S
V
T
R
K
T
S
F
A
A
L
L
K
S
Site 83
S768
S
F
A
A
L
L
K
S
Q
H
N
K
W
K
L
Site 84
Y779
K
W
K
L
A
N
Q
Y
E
K
F
H
S
P
R
Site 85
S784
N
Q
Y
E
K
F
H
S
P
R
E
R
E
E
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation