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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Fox-1 homolog C
Full Name:
Fox-1 homolog C
Alias:
Fox-1 homolog C
Type:
Mass (Da):
38102
Number AA:
350
UniProt ID:
A6NFN3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
Q
P
Y
P
P
A
Q
Y
P
P
P
P
Q
N
G
Site 2
Y22
Q
N
G
I
P
A
E
Y
A
P
P
P
P
H
P
Site 3
T30
A
P
P
P
P
H
P
T
Q
D
Y
S
G
Q
T
Site 4
Y33
P
P
H
P
T
Q
D
Y
S
G
Q
T
P
V
P
Site 5
T37
T
Q
D
Y
S
G
Q
T
P
V
P
T
E
H
G
Site 6
T41
S
G
Q
T
P
V
P
T
E
H
G
M
T
L
Y
Site 7
Y48
T
E
H
G
M
T
L
Y
T
P
A
Q
T
H
P
Site 8
T49
E
H
G
M
T
L
Y
T
P
A
Q
T
H
P
E
Site 9
S60
T
H
P
E
Q
P
G
S
E
A
S
T
Q
P
I
Site 10
S63
E
Q
P
G
S
E
A
S
T
Q
P
I
A
G
T
Site 11
T64
Q
P
G
S
E
A
S
T
Q
P
I
A
G
T
Q
Site 12
T72
Q
P
I
A
G
T
Q
T
V
P
Q
T
D
E
A
Site 13
T82
Q
T
D
E
A
A
Q
T
D
S
Q
P
L
H
P
Site 14
S84
D
E
A
A
Q
T
D
S
Q
P
L
H
P
S
D
Site 15
S90
D
S
Q
P
L
H
P
S
D
P
T
E
K
Q
Q
Site 16
T93
P
L
H
P
S
D
P
T
E
K
Q
Q
P
K
R
Site 17
S104
Q
P
K
R
L
H
V
S
N
I
P
F
R
F
R
Site 18
T144
S
K
G
F
G
F
V
T
F
E
T
S
S
D
A
Site 19
T179
N
A
T
A
R
V
M
T
N
K
K
T
G
N
P
Site 20
T183
R
V
M
T
N
K
K
T
G
N
P
Y
T
N
G
Site 21
Y187
N
K
K
T
G
N
P
Y
T
N
G
W
K
L
N
Site 22
T188
K
K
T
G
N
P
Y
T
N
G
W
K
L
N
P
Site 23
T209
G
P
E
F
Y
A
V
T
G
F
P
Y
P
T
T
Site 24
T216
T
G
F
P
Y
P
T
T
G
T
A
V
A
Y
R
Site 25
Y235
R
G
R
G
R
A
V
Y
N
T
F
R
A
A
P
Site 26
T237
R
G
R
A
V
Y
N
T
F
R
A
A
P
P
P
Site 27
Y250
P
P
P
P
I
P
T
Y
G
A
V
V
Y
Q
D
Site 28
Y255
P
T
Y
G
A
V
V
Y
Q
D
G
F
Y
G
A
Site 29
Y273
G
G
Y
A
A
Y
R
Y
A
Q
P
A
A
A
A
Site 30
S284
A
A
A
A
A
A
Y
S
D
S
Y
G
R
V
Y
Site 31
Y287
A
A
A
Y
S
D
S
Y
G
R
V
Y
A
A
A
Site 32
Y291
S
D
S
Y
G
R
V
Y
A
A
A
D
P
Y
H
Site 33
Y297
V
Y
A
A
A
D
P
Y
H
H
T
I
G
P
A
Site 34
T300
A
A
D
P
Y
H
H
T
I
G
P
A
A
T
Y
Site 35
T323
H
P
A
S
K
M
K
T
S
W
E
S
E
E
G
Site 36
S324
P
A
S
K
M
K
T
S
W
E
S
E
E
G
G
Site 37
Y344
A
S
L
C
R
G
G
Y
S
R
F
T
P
Y
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation