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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WIPF3
Full Name:
WAS/WASL-interacting protein family member 3
Alias:
Corticosteroids and regional expression protein 16 homolog
Type:
Mass (Da):
49348
Number AA:
483
UniProt ID:
A6NGB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
A
P
P
P
P
P
P
S
A
P
P
V
S
T
D
Site 2
S32
P
P
S
A
P
P
V
S
T
D
T
S
S
L
R
Site 3
T33
P
S
A
P
P
V
S
T
D
T
S
S
L
R
R
Site 4
S36
P
P
V
S
T
D
T
S
S
L
R
R
A
D
P
Site 5
S37
P
V
S
T
D
T
S
S
L
R
R
A
D
P
K
Site 6
T63
G
T
R
L
R
K
V
T
Q
I
N
D
R
S
A
Site 7
S69
V
T
Q
I
N
D
R
S
A
P
Q
I
E
S
S
Site 8
T79
Q
I
E
S
S
K
G
T
N
K
E
G
G
G
S
Site 9
S86
T
N
K
E
G
G
G
S
A
N
T
R
G
A
S
Site 10
S93
S
A
N
T
R
G
A
S
T
P
P
T
L
G
D
Site 11
T94
A
N
T
R
G
A
S
T
P
P
T
L
G
D
L
Site 12
T97
R
G
A
S
T
P
P
T
L
G
D
L
F
A
G
Site 13
S128
K
T
G
Q
G
P
G
S
R
A
P
S
P
R
L
Site 14
S132
G
P
G
S
R
A
P
S
P
R
L
P
N
K
T
Site 15
T139
S
P
R
L
P
N
K
T
I
S
G
P
L
I
P
Site 16
S141
R
L
P
N
K
T
I
S
G
P
L
I
P
P
A
Site 17
S149
G
P
L
I
P
P
A
S
P
R
L
G
N
T
S
Site 18
T155
A
S
P
R
L
G
N
T
S
E
A
H
G
A
A
Site 19
S156
S
P
R
L
G
N
T
S
E
A
H
G
A
A
R
Site 20
T164
E
A
H
G
A
A
R
T
A
P
P
R
P
N
V
Site 21
T178
V
P
A
P
P
P
P
T
P
P
P
P
P
P
P
Site 22
S192
P
L
P
P
P
L
P
S
S
S
P
I
K
T
P
Site 23
S193
L
P
P
P
L
P
S
S
S
P
I
K
T
P
L
Site 24
S194
P
P
P
L
P
S
S
S
P
I
K
T
P
L
V
Site 25
T198
P
S
S
S
P
I
K
T
P
L
V
S
P
P
G
Site 26
S202
P
I
K
T
P
L
V
S
P
P
G
P
L
T
K
Site 27
T233
P
P
P
P
P
P
P
T
P
P
P
L
P
P
A
Site 28
Y272
P
L
L
P
P
C
G
Y
P
G
L
K
A
E
P
Site 29
S281
G
L
K
A
E
P
A
S
P
A
Q
D
A
Q
E
Site 30
Y299
P
P
P
P
L
P
P
Y
A
S
C
S
P
R
A
Site 31
S301
P
P
L
P
P
Y
A
S
C
S
P
R
A
S
L
Site 32
S303
L
P
P
Y
A
S
C
S
P
R
A
S
L
P
A
Site 33
S307
A
S
C
S
P
R
A
S
L
P
A
P
P
L
P
Site 34
S318
P
P
L
P
G
V
N
S
S
S
E
T
P
P
P
Site 35
S319
P
L
P
G
V
N
S
S
S
E
T
P
P
P
L
Site 36
S320
L
P
G
V
N
S
S
S
E
T
P
P
P
L
P
Site 37
T322
G
V
N
S
S
S
E
T
P
P
P
L
P
P
K
Site 38
S330
P
P
P
L
P
P
K
S
P
S
F
Q
A
P
P
Site 39
S332
P
L
P
P
K
S
P
S
F
Q
A
P
P
Q
K
Site 40
S354
A
P
P
A
P
P
G
S
Q
P
F
L
Q
K
K
Site 41
S383
P
P
A
P
P
A
R
S
P
T
T
E
L
S
S
Site 42
T385
A
P
P
A
R
S
P
T
T
E
L
S
S
K
S
Site 43
T386
P
P
A
R
S
P
T
T
E
L
S
S
K
S
Q
Site 44
S389
R
S
P
T
T
E
L
S
S
K
S
Q
Q
A
T
Site 45
S390
S
P
T
T
E
L
S
S
K
S
Q
Q
A
T
A
Site 46
S392
T
T
E
L
S
S
K
S
Q
Q
A
T
A
W
T
Site 47
T396
S
S
K
S
Q
Q
A
T
A
W
T
P
T
Q
Q
Site 48
T399
S
Q
Q
A
T
A
W
T
P
T
Q
Q
P
G
G
Site 49
T401
Q
A
T
A
W
T
P
T
Q
Q
P
G
G
Q
L
Site 50
S412
G
G
Q
L
R
N
G
S
L
H
I
I
D
D
F
Site 51
T424
D
D
F
E
S
K
F
T
F
H
S
V
E
D
F
Site 52
S427
E
S
K
F
T
F
H
S
V
E
D
F
P
P
P
Site 53
Y437
D
F
P
P
P
D
E
Y
K
P
C
Q
K
I
Y
Site 54
Y444
Y
K
P
C
Q
K
I
Y
P
S
K
I
P
R
S
Site 55
S446
P
C
Q
K
I
Y
P
S
K
I
P
R
S
R
T
Site 56
S451
Y
P
S
K
I
P
R
S
R
T
P
G
P
W
L
Site 57
T453
S
K
I
P
R
S
R
T
P
G
P
W
L
Q
A
Site 58
S467
A
E
A
V
G
Q
S
S
D
D
I
K
G
R
N
Site 59
S475
D
D
I
K
G
R
N
S
Q
V
T
Q
A
S
C
Site 60
T478
K
G
R
N
S
Q
V
T
Q
A
S
C
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation