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Updated November 2019
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Protein Info
Short Name:
PRAMEF25
Full Name:
Putative PRAME family member 25
Alias:
Type:
Mass (Da):
54317
Number AA:
474
UniProt ID:
A6NGN4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S123
W
S
G
A
R
P
L
S
C
S
P
E
A
M
S
Site 2
S125
G
A
R
P
L
S
C
S
P
E
A
M
S
K
R
Site 3
S130
S
C
S
P
E
A
M
S
K
R
Q
T
V
E
D
Site 4
T134
E
A
M
S
K
R
Q
T
V
E
D
C
P
R
T
Site 5
T141
T
V
E
D
C
P
R
T
G
E
K
Q
P
L
K
Site 6
T201
N
F
R
N
I
L
E
T
V
Y
P
D
S
I
Q
Site 7
S229
V
E
F
S
P
Y
L
S
Q
M
R
N
L
R
K
Site 8
Y245
F
I
S
D
G
C
R
Y
L
L
S
S
D
S
Q
Site 9
S248
D
G
C
R
Y
L
L
S
S
D
S
Q
E
Q
I
Site 10
S249
G
C
R
Y
L
L
S
S
D
S
Q
E
Q
I
A
Site 11
S251
R
Y
L
L
S
S
D
S
Q
E
Q
I
A
P
F
Site 12
S275
L
Q
K
L
Y
M
N
S
V
S
F
L
E
G
H
Site 13
S277
K
L
Y
M
N
S
V
S
F
L
E
G
H
L
D
Site 14
S288
G
H
L
D
Q
L
L
S
C
L
K
T
S
L
K
Site 15
S313
E
S
D
L
K
H
L
S
Q
C
P
S
I
S
Q
Site 16
S317
K
H
L
S
Q
C
P
S
I
S
Q
L
K
T
L
Site 17
T323
P
S
I
S
Q
L
K
T
L
D
L
S
G
I
R
Site 18
S327
Q
L
K
T
L
D
L
S
G
I
R
L
T
N
Y
Site 19
T392
G
N
P
I
S
M
A
T
L
E
N
L
L
S
H
Site 20
Y411
K
N
L
C
L
E
L
Y
P
A
P
R
E
S
Y
Site 21
S417
L
Y
P
A
P
R
E
S
Y
G
A
D
G
T
L
Site 22
Y418
Y
P
A
P
R
E
S
Y
G
A
D
G
T
L
C
Site 23
T423
E
S
Y
G
A
D
G
T
L
C
W
S
R
F
T
Site 24
T453
P
K
R
I
L
F
G
T
D
Y
C
P
D
C
G
Site 25
Y455
R
I
L
F
G
T
D
Y
C
P
D
C
G
N
R
Site 26
S463
C
P
D
C
G
N
R
S
F
Y
D
L
E
A
D
Site 27
Y465
D
C
G
N
R
S
F
Y
D
L
E
A
D
Q
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation