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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OTOL1
Full Name:
Otolin-1
Alias:
Type:
Uncharacterized protein
Mass (Da):
49422
Number AA:
477
UniProt ID:
A6NHN0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
M
N
T
I
A
K
T
T
P
H
T
K
F
T
K
Site 2
S35
H
T
K
F
T
K
K
S
E
E
R
E
M
P
K
Site 3
S47
M
P
K
G
L
K
P
S
S
G
P
P
P
E
E
Site 4
S48
P
K
G
L
K
P
S
S
G
P
P
P
E
E
E
Site 5
T57
P
P
P
E
E
E
E
T
L
F
T
E
M
A
E
Site 6
T60
E
E
E
E
T
L
F
T
E
M
A
E
M
A
E
Site 7
S73
A
E
P
I
T
K
P
S
A
L
D
S
V
F
G
Site 8
T118
Q
K
G
E
P
G
E
T
G
Q
P
G
P
K
G
Site 9
Y147
G
P
Q
G
P
R
G
Y
K
G
E
K
G
L
K
Site 10
Y165
G
D
Q
G
V
P
G
Y
P
G
K
P
G
A
Q
Site 11
T199
Q
K
G
S
K
G
D
T
C
G
N
C
T
K
G
Site 12
S216
G
D
Q
G
A
M
G
S
P
G
L
H
G
G
P
Site 13
S247
D
K
G
C
C
G
D
S
G
E
R
G
G
K
G
Site 14
S267
G
M
K
G
E
K
G
S
K
G
D
S
G
M
E
Site 15
S271
E
K
G
S
K
G
D
S
G
M
E
G
K
S
G
Site 16
S277
D
S
G
M
E
G
K
S
G
R
N
G
L
P
G
Site 17
T322
N
K
G
V
R
G
P
T
G
K
K
G
S
R
G
Site 18
S327
G
P
T
G
K
K
G
S
R
G
F
K
G
S
K
Site 19
S333
G
S
R
G
F
K
G
S
K
G
E
L
A
R
V
Site 20
S346
R
V
P
R
S
A
F
S
A
G
L
S
K
P
F
Site 21
S350
S
A
F
S
A
G
L
S
K
P
F
P
P
P
N
Site 22
Y367
I
K
F
E
K
I
L
Y
N
D
Q
G
N
Y
S
Site 23
Y373
L
Y
N
D
Q
G
N
Y
S
P
V
T
G
K
F
Site 24
S374
Y
N
D
Q
G
N
Y
S
P
V
T
G
K
F
N
Site 25
T377
Q
G
N
Y
S
P
V
T
G
K
F
N
C
S
I
Site 26
Y388
N
C
S
I
P
G
T
Y
V
F
S
Y
H
I
T
Site 27
Y392
P
G
T
Y
V
F
S
Y
H
I
T
V
R
G
R
Site 28
T395
Y
V
F
S
Y
H
I
T
V
R
G
R
P
A
R
Site 29
S404
R
G
R
P
A
R
I
S
L
V
A
Q
N
K
K
Site 30
S415
Q
N
K
K
Q
F
K
S
R
E
T
L
Y
G
Q
Site 31
T418
K
Q
F
K
S
R
E
T
L
Y
G
Q
E
I
D
Site 32
Y453
S
K
D
W
N
G
V
Y
V
S
A
E
D
D
S
Site 33
T472
F
L
L
Y
P
E
E
T
S
G
I
S
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation