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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NCF1B
Full Name:
Putative neutrophil cytosol factor 1B
Alias:
SH3PXD1B
Type:
Regulatory protein - NADPH oxidase activator
Mass (Da):
44817
Number AA:
391
UniProt ID:
A6NI72
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
L
V
K
W
Q
D
L
S
E
K
V
V
Y
R
R
Site 2
Y42
D
L
S
E
K
V
V
Y
R
R
F
T
E
I
Y
Site 3
T46
K
V
V
Y
R
R
F
T
E
I
Y
E
F
H
K
Site 4
Y49
Y
R
R
F
T
E
I
Y
E
F
H
K
T
L
K
Site 5
T54
E
I
Y
E
F
H
K
T
L
K
E
M
F
P
I
Site 6
T96
E
N
H
Q
G
T
L
T
E
Y
C
G
T
L
M
Site 7
Y98
H
Q
G
T
L
T
E
Y
C
G
T
L
M
S
L
Site 8
S104
E
Y
C
G
T
L
M
S
L
P
T
K
I
S
R
Site 9
S110
M
S
L
P
T
K
I
S
R
C
P
H
L
L
D
Site 10
T134
K
L
P
T
D
N
Q
T
K
K
P
E
T
Y
L
Site 11
Y140
Q
T
K
K
P
E
T
Y
L
M
P
K
D
G
K
Site 12
S148
L
M
P
K
D
G
K
S
T
A
T
D
I
T
G
Site 13
Y168
T
Y
R
A
I
A
N
Y
E
K
T
S
G
S
E
Site 14
S174
N
Y
E
K
T
S
G
S
E
M
A
L
S
T
G
Site 15
S209
K
R
G
W
I
P
A
S
F
L
E
P
L
D
S
Site 16
S216
S
F
L
E
P
L
D
S
P
D
E
T
E
D
P
Site 17
T220
P
L
D
S
P
D
E
T
E
D
P
E
P
N
Y
Site 18
Y227
T
E
D
P
E
P
N
Y
A
G
E
P
Y
V
A
Site 19
Y232
P
N
Y
A
G
E
P
Y
V
A
I
K
A
Y
T
Site 20
Y238
P
Y
V
A
I
K
A
Y
T
A
V
E
G
D
E
Site 21
T273
V
I
R
K
D
D
V
T
G
Y
F
P
S
M
Y
Site 22
Y275
R
K
D
D
V
T
G
Y
F
P
S
M
Y
L
Q
Site 23
S278
D
V
T
G
Y
F
P
S
M
Y
L
Q
K
S
G
Site 24
Y280
T
G
Y
F
P
S
M
Y
L
Q
K
S
G
Q
D
Site 25
S284
P
S
M
Y
L
Q
K
S
G
Q
D
V
S
Q
A
Site 26
S289
Q
K
S
G
Q
D
V
S
Q
A
Q
R
Q
I
K
Site 27
S304
R
G
A
P
P
R
R
S
S
I
R
N
V
H
S
Site 28
S305
G
A
P
P
R
R
S
S
I
R
N
V
H
S
I
Site 29
S311
S
S
I
R
N
V
H
S
I
H
Q
R
S
R
K
Site 30
S316
V
H
S
I
H
Q
R
S
R
K
R
L
S
Q
D
Site 31
S321
Q
R
S
R
K
R
L
S
Q
D
A
Y
R
R
N
Site 32
Y325
K
R
L
S
Q
D
A
Y
R
R
N
S
V
R
F
Site 33
S329
Q
D
A
Y
R
R
N
S
V
R
F
L
Q
Q
R
Site 34
S346
Q
A
R
P
G
P
Q
S
P
G
S
P
L
E
E
Site 35
S349
P
G
P
Q
S
P
G
S
P
L
E
E
E
R
Q
Site 36
T357
P
L
E
E
E
R
Q
T
Q
R
S
K
P
Q
P
Site 37
S360
E
E
R
Q
T
Q
R
S
K
P
Q
P
A
V
P
Site 38
S371
P
A
V
P
P
R
P
S
A
D
L
I
L
N
R
Site 39
S380
D
L
I
L
N
R
C
S
E
S
T
K
R
K
L
Site 40
S382
I
L
N
R
C
S
E
S
T
K
R
K
L
A
S
Site 41
T383
L
N
R
C
S
E
S
T
K
R
K
L
A
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation