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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WTIP
Full Name:
Wilms tumor protein 1-interacting protein
Alias:
WT1-interacting protein
Type:
Uncharacterized protein
Mass (Da):
67454
Number AA:
654
UniProt ID:
A6NIX2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005912
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
G
P
P
L
E
A
S
P
T
T
L
D
A
A
Site 2
T15
P
P
L
E
A
S
P
T
T
L
D
A
A
V
R
Site 3
S45
A
G
G
R
G
D
A
S
A
L
G
A
Q
Y
S
Site 4
S52
S
A
L
G
A
Q
Y
S
W
A
R
D
G
R
S
Site 5
S59
S
W
A
R
D
G
R
S
A
V
G
S
K
L
S
Site 6
S63
D
G
R
S
A
V
G
S
K
L
S
W
V
G
P
Site 7
S75
V
G
P
A
A
P
E
S
K
A
A
Q
G
R
E
Site 8
S112
L
Q
L
S
L
R
K
S
E
L
F
P
A
A
R
Site 9
S130
R
P
A
D
P
G
L
S
P
R
C
L
R
R
P
Site 10
S145
P
L
R
P
G
P
A
S
T
P
L
R
G
P
G
Site 11
T146
L
R
P
G
P
A
S
T
P
L
R
G
P
G
A
Site 12
S163
P
P
P
L
P
P
H
S
R
G
R
S
A
V
S
Site 13
S167
P
P
H
S
R
G
R
S
A
V
S
F
L
A
F
Site 14
S180
A
F
L
P
P
Q
R
S
P
S
A
P
R
E
A
Site 15
S182
L
P
P
Q
R
S
P
S
A
P
R
E
A
A
G
Site 16
S190
A
P
R
E
A
A
G
S
R
G
G
L
R
A
S
Site 17
S197
S
R
G
G
L
R
A
S
G
G
R
C
G
G
P
Site 18
S228
A
G
R
A
M
Q
R
S
R
A
G
A
D
E
A
Site 19
S253
E
L
E
P
G
C
G
S
P
G
R
G
R
R
G
Site 20
S280
L
G
R
R
G
K
G
S
G
G
P
E
A
G
A
Site 21
S291
E
A
G
A
D
G
L
S
R
G
E
R
G
P
R
Site 22
S306
R
A
A
V
P
E
L
S
A
Q
P
A
G
S
P
Site 23
S312
L
S
A
Q
P
A
G
S
P
R
A
S
L
A
G
Site 24
S316
P
A
G
S
P
R
A
S
L
A
G
S
D
G
G
Site 25
S320
P
R
A
S
L
A
G
S
D
G
G
G
G
G
G
Site 26
S328
D
G
G
G
G
G
G
S
A
R
S
S
G
I
S
Site 27
S331
G
G
G
G
S
A
R
S
S
G
I
S
L
G
Y
Site 28
S332
G
G
G
S
A
R
S
S
G
I
S
L
G
Y
D
Site 29
S335
S
A
R
S
S
G
I
S
L
G
Y
D
Q
R
H
Site 30
Y338
S
S
G
I
S
L
G
Y
D
Q
R
H
G
S
P
Site 31
S344
G
Y
D
Q
R
H
G
S
P
R
S
G
R
S
D
Site 32
S347
Q
R
H
G
S
P
R
S
G
R
S
D
P
R
P
Site 33
S350
G
S
P
R
S
G
R
S
D
P
R
P
G
P
G
Site 34
S360
R
P
G
P
G
P
P
S
V
G
S
A
R
S
S
Site 35
S363
P
G
P
P
S
V
G
S
A
R
S
S
V
S
S
Site 36
S366
P
S
V
G
S
A
R
S
S
V
S
S
L
G
S
Site 37
S367
S
V
G
S
A
R
S
S
V
S
S
L
G
S
R
Site 38
S369
G
S
A
R
S
S
V
S
S
L
G
S
R
G
S
Site 39
S370
S
A
R
S
S
V
S
S
L
G
S
R
G
S
A
Site 40
S373
S
S
V
S
S
L
G
S
R
G
S
A
G
A
Y
Site 41
S376
S
S
L
G
S
R
G
S
A
G
A
Y
A
D
F
Site 42
Y380
S
R
G
S
A
G
A
Y
A
D
F
L
P
P
G
Site 43
S395
A
C
P
A
P
A
R
S
P
E
P
A
G
P
A
Site 44
S420
P
G
R
E
G
G
P
S
A
A
E
R
R
L
E
Site 45
T430
E
R
R
L
E
A
L
T
R
E
L
E
R
A
L
Site 46
Y445
E
A
R
T
A
R
D
Y
F
G
I
C
I
K
C
Site 47
Y490
R
L
R
G
K
A
F
Y
N
V
G
E
K
V
Y
Site 48
Y504
Y
C
Q
E
D
F
L
Y
S
G
F
Q
Q
T
A
Site 49
Y561
V
D
V
E
N
N
I
Y
C
V
R
D
Y
H
T
Site 50
Y566
N
I
Y
C
V
R
D
Y
H
T
V
F
A
P
K
Site 51
T590
P
A
Q
G
C
E
T
T
I
R
V
V
S
M
D
Site 52
S595
E
T
T
I
R
V
V
S
M
D
R
D
Y
H
V
Site 53
S615
E
D
C
G
L
Q
L
S
G
E
E
G
R
R
C
Site 54
Y623
G
E
E
G
R
R
C
Y
P
L
A
G
H
L
L
Site 55
S646
L
Q
P
G
P
L
P
S
P
T
V
H
V
T
E
Site 56
T648
P
G
P
L
P
S
P
T
V
H
V
T
E
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation