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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NKX6-3
Full Name:
Homeobox protein Nkx-6.3
Alias:
Type:
Mass (Da):
28948
Number AA:
265
UniProt ID:
A6NJ46
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
G
T
F
L
L
N
N
T
P
L
A
Q
F
P
E
Site 2
S34
C
Q
Y
S
V
Q
N
S
F
Y
K
L
S
P
P
Site 3
Y36
Y
S
V
Q
N
S
F
Y
K
L
S
P
P
G
L
Site 4
S39
Q
N
S
F
Y
K
L
S
P
P
G
L
G
P
Q
Site 5
T51
G
P
Q
L
A
A
G
T
P
H
G
I
T
D
I
Site 6
S60
H
G
I
T
D
I
L
S
R
P
V
A
A
P
N
Site 7
S72
A
P
N
N
S
L
L
S
G
Y
P
H
V
A
G
Site 8
Y74
N
N
S
L
L
S
G
Y
P
H
V
A
G
F
G
Site 9
S85
A
G
F
G
G
L
S
S
Q
G
V
Y
Y
S
P
Site 10
Y89
G
L
S
S
Q
G
V
Y
Y
S
P
Q
V
G
N
Site 11
Y90
L
S
S
Q
G
V
Y
Y
S
P
Q
V
G
N
F
Site 12
S91
S
S
Q
G
V
Y
Y
S
P
Q
V
G
N
F
S
Site 13
Y104
F
S
K
A
G
N
E
Y
P
T
R
T
R
N
C
Site 14
S126
W
R
G
G
R
Q
C
S
N
T
P
D
P
L
S
Site 15
T128
G
G
R
Q
C
S
N
T
P
D
P
L
S
D
S
Site 16
S133
S
N
T
P
D
P
L
S
D
S
I
H
K
K
K
Site 17
S135
T
P
D
P
L
S
D
S
I
H
K
K
K
H
T
Site 18
T145
K
K
K
H
T
R
P
T
F
T
G
H
Q
I
F
Site 19
T157
Q
I
F
A
L
E
K
T
F
E
Q
T
K
Y
L
Site 20
Y163
K
T
F
E
Q
T
K
Y
L
A
G
P
E
R
A
Site 21
Y174
P
E
R
A
R
L
A
Y
S
L
G
M
T
E
S
Site 22
S175
E
R
A
R
L
A
Y
S
L
G
M
T
E
S
Q
Site 23
S198
R
T
K
W
R
K
K
S
A
L
E
P
S
S
S
Site 24
S204
K
S
A
L
E
P
S
S
S
T
P
R
A
P
G
Site 25
S205
S
A
L
E
P
S
S
S
T
P
R
A
P
G
G
Site 26
T206
A
L
E
P
S
S
S
T
P
R
A
P
G
G
A
Site 27
S224
A
G
G
D
R
A
P
S
E
N
E
D
D
E
Y
Site 28
Y231
S
E
N
E
D
D
E
Y
N
K
P
L
D
P
D
Site 29
S239
N
K
P
L
D
P
D
S
D
D
E
K
I
R
L
Site 30
S256
R
K
H
R
A
A
F
S
V
L
S
L
G
A
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation