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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARGFX
Full Name:
Arginine-fifty homeobox
Alias:
Type:
Mass (Da):
35617
Number AA:
315
UniProt ID:
A6NJG6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
D
P
F
I
N
R
N
Y
S
N
M
K
V
I
P
Site 2
S33
I
P
P
Q
D
P
A
S
P
S
F
T
L
L
S
Site 3
S35
P
Q
D
P
A
S
P
S
F
T
L
L
S
K
L
Site 4
T37
D
P
A
S
P
S
F
T
L
L
S
K
L
E
C
Site 5
S40
S
P
S
F
T
L
L
S
K
L
E
C
S
G
T
Site 6
S59
C
S
L
N
L
P
G
S
T
D
P
P
T
S
A
Site 7
T60
S
L
N
L
P
G
S
T
D
P
P
T
S
A
S
Site 8
T64
P
G
S
T
D
P
P
T
S
A
S
R
V
A
A
Site 9
S65
G
S
T
D
P
P
T
S
A
S
R
V
A
A
T
Site 10
S67
T
D
P
P
T
S
A
S
R
V
A
A
T
T
A
Site 11
T73
A
S
R
V
A
A
T
T
A
I
R
R
R
H
K
Site 12
T83
R
R
R
H
K
E
R
T
S
F
T
H
Q
Q
Y
Site 13
S84
R
R
H
K
E
R
T
S
F
T
H
Q
Q
Y
E
Site 14
S98
E
E
L
E
A
L
F
S
Q
T
M
F
P
D
R
Site 15
S120
L
R
L
D
L
P
E
S
T
V
K
V
W
F
R
Site 16
S151
Q
R
N
Q
I
L
P
S
K
K
N
V
P
T
S
Site 17
T157
P
S
K
K
N
V
P
T
S
P
R
T
S
P
S
Site 18
S158
S
K
K
N
V
P
T
S
P
R
T
S
P
S
P
Site 19
S162
V
P
T
S
P
R
T
S
P
S
P
Y
A
F
S
Site 20
S164
T
S
P
R
T
S
P
S
P
Y
A
F
S
P
V
Site 21
S169
S
P
S
P
Y
A
F
S
P
V
I
S
D
F
Y
Site 22
Y176
S
P
V
I
S
D
F
Y
S
S
L
P
S
Q
P
Site 23
S177
P
V
I
S
D
F
Y
S
S
L
P
S
Q
P
L
Site 24
S178
V
I
S
D
F
Y
S
S
L
P
S
Q
P
L
D
Site 25
S181
D
F
Y
S
S
L
P
S
Q
P
L
D
P
S
N
Site 26
S187
P
S
Q
P
L
D
P
S
N
W
A
W
N
S
T
Site 27
S193
P
S
N
W
A
W
N
S
T
F
T
E
S
S
T
Site 28
T194
S
N
W
A
W
N
S
T
F
T
E
S
S
T
S
Site 29
S201
T
F
T
E
S
S
T
S
D
F
Q
M
Q
D
T
Site 30
S216
Q
W
E
R
L
V
A
S
V
P
A
L
Y
S
D
Site 31
Y234
I
F
Q
I
I
E
L
Y
N
L
P
D
E
N
E
Site 32
S243
L
P
D
E
N
E
I
S
S
S
S
F
H
C
L
Site 33
S245
D
E
N
E
I
S
S
S
S
F
H
C
L
Y
Q
Site 34
S246
E
N
E
I
S
S
S
S
F
H
C
L
Y
Q
Y
Site 35
Y251
S
S
S
F
H
C
L
Y
Q
Y
L
S
P
T
K
Site 36
Y253
S
F
H
C
L
Y
Q
Y
L
S
P
T
K
Y
Q
Site 37
Y259
Q
Y
L
S
P
T
K
Y
Q
V
G
G
Q
G
S
Site 38
S279
A
G
P
A
V
G
L
S
P
A
Q
T
W
P
N
Site 39
T283
V
G
L
S
P
A
Q
T
W
P
N
M
T
S
Q
Site 40
S296
S
Q
A
F
E
A
Y
S
L
T
D
S
L
E
F
Site 41
T298
A
F
E
A
Y
S
L
T
D
S
L
E
F
Q
K
Site 42
S300
E
A
Y
S
L
T
D
S
L
E
F
Q
K
T
S
Site 43
T306
D
S
L
E
F
Q
K
T
S
N
M
V
D
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation