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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM75
Full Name:
Tripartite motif-containing protein 75
Alias:
Type:
Mass (Da):
53678
Number AA:
468
UniProt ID:
A6NK02
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
D
Y
L
S
D
P
V
T
I
E
C
G
H
N
F
Site 2
T69
E
G
H
F
R
S
N
T
Q
L
G
R
M
I
E
Site 3
S86
K
L
L
Q
S
T
K
S
N
K
R
K
Q
E
E
Site 4
T94
N
K
R
K
Q
E
E
T
T
L
C
E
K
H
N
Site 5
S105
E
K
H
N
Q
P
L
S
V
F
C
K
E
D
L
Site 6
Y140
I
E
K
A
A
I
H
Y
R
K
R
F
C
S
Y
Site 7
Y147
Y
R
K
R
F
C
S
Y
I
Q
P
L
K
K
Q
Site 8
S163
A
D
L
Q
K
L
I
S
T
Q
S
K
K
P
L
Site 9
T164
D
L
Q
K
L
I
S
T
Q
S
K
K
P
L
E
Site 10
S166
Q
K
L
I
S
T
Q
S
K
K
P
L
E
L
R
Site 11
S185
N
Q
R
Q
E
L
S
S
E
F
E
H
L
N
Q
Site 12
T221
Q
K
L
S
A
N
I
T
A
F
S
N
Y
S
A
Site 13
S224
S
A
N
I
T
A
F
S
N
Y
S
A
T
L
K
Site 14
S227
I
T
A
F
S
N
Y
S
A
T
L
K
S
Q
L
Site 15
T229
A
F
S
N
Y
S
A
T
L
K
S
Q
L
S
K
Site 16
S232
N
Y
S
A
T
L
K
S
Q
L
S
K
V
V
E
Site 17
S235
A
T
L
K
S
Q
L
S
K
V
V
E
L
S
E
Site 18
Y256
L
S
Q
I
K
I
F
Y
E
S
E
N
E
S
S
Site 19
S258
Q
I
K
I
F
Y
E
S
E
N
E
S
S
P
S
Site 20
S262
F
Y
E
S
E
N
E
S
S
P
S
I
F
S
I
Site 21
S263
Y
E
S
E
N
E
S
S
P
S
I
F
S
I
H
Site 22
S265
S
E
N
E
S
S
P
S
I
F
S
I
H
L
K
Site 23
S277
H
L
K
R
D
G
C
S
F
P
P
Q
Y
S
A
Site 24
Y282
G
C
S
F
P
P
Q
Y
S
A
L
Q
R
I
I
Site 25
S283
C
S
F
P
P
Q
Y
S
A
L
Q
R
I
I
K
Site 26
S310
A
H
P
N
L
I
V
S
E
D
K
K
R
V
R
Site 27
T319
D
K
K
R
V
R
F
T
K
R
K
Q
K
V
P
Site 28
S369
A
I
G
I
C
K
D
S
L
P
T
K
A
R
R
Site 29
S378
P
T
K
A
R
R
P
S
S
A
Q
Q
E
C
W
Site 30
S379
T
K
A
R
R
P
S
S
A
Q
Q
E
C
W
R
Site 31
Y394
I
E
L
Q
D
D
G
Y
H
A
P
G
A
F
P
Site 32
Y427
E
M
G
E
I
S
F
Y
N
M
A
E
K
S
H
Site 33
T437
A
E
K
S
H
I
C
T
F
T
D
T
F
T
G
Site 34
T441
H
I
C
T
F
T
D
T
F
T
G
P
L
R
P
Site 35
T443
C
T
F
T
D
T
F
T
G
P
L
R
P
Y
F
Site 36
Y449
F
T
G
P
L
R
P
Y
F
Y
V
G
P
D
S
Site 37
Y451
G
P
L
R
P
Y
F
Y
V
G
P
D
S
Q
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation