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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RTL1
Full Name:
Retrotransposon-like protein 1
Alias:
Mammalian retrotransposon derived protein 1;Paternally expressed gene 11 protein;Retrotransposon-derived protein PEG11
Type:
Mass (Da):
155177
Number AA:
1359
UniProt ID:
A6NKG5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
I
E
P
S
E
D
S
F
E
T
M
M
E
H
Site 2
S19
M
M
E
H
K
N
P
S
S
K
Q
M
E
S
S
Site 3
S20
M
E
H
K
N
P
S
S
K
Q
M
E
S
S
E
Site 4
S25
P
S
S
K
Q
M
E
S
S
E
G
S
S
N
T
Site 5
S26
S
S
K
Q
M
E
S
S
E
G
S
S
N
T
T
Site 6
S29
Q
M
E
S
S
E
G
S
S
N
T
T
E
A
T
Site 7
S30
M
E
S
S
E
G
S
S
N
T
T
E
A
T
S
Site 8
T32
S
S
E
G
S
S
N
T
T
E
A
T
S
G
S
Site 9
T33
S
E
G
S
S
N
T
T
E
A
T
S
G
S
G
Site 10
S37
S
N
T
T
E
A
T
S
G
S
G
V
R
G
E
Site 11
S39
T
T
E
A
T
S
G
S
G
V
R
G
E
A
G
Site 12
S49
R
G
E
A
G
P
A
S
G
P
A
Q
E
K
K
Site 13
S60
Q
E
K
K
E
P
P
S
G
P
L
Q
E
M
E
Site 14
T71
Q
E
M
E
E
L
P
T
D
L
L
Q
D
M
E
Site 15
S82
Q
D
M
E
E
P
S
S
G
P
R
K
E
I
E
Site 16
S106
L
E
E
S
C
N
G
S
H
Q
A
R
G
D
P
Site 17
S115
Q
A
R
G
D
P
L
S
G
A
S
D
R
M
K
Site 18
S118
G
D
P
L
S
G
A
S
D
R
M
K
E
A
S
Site 19
S125
S
D
R
M
K
E
A
S
V
N
P
S
G
A
R
Site 20
S129
K
E
A
S
V
N
P
S
G
A
R
E
E
Q
E
Site 21
T149
K
E
S
G
R
E
E
T
P
Q
E
E
Q
N
Q
Site 22
T157
P
Q
E
E
Q
N
Q
T
E
H
S
T
A
E
L
Site 23
S208
L
P
A
P
K
H
F
S
G
D
R
R
E
F
H
Site 24
Y228
C
Q
L
T
L
Q
S
Y
P
R
M
F
Y
N
D
Site 25
Y233
Q
S
Y
P
R
M
F
Y
N
D
R
L
R
V
G
Site 26
Y241
N
D
R
L
R
V
G
Y
V
I
N
H
L
S
G
Site 27
S262
K
A
L
L
Q
E
N
S
P
L
I
G
D
F
P
Site 28
Y281
A
M
S
E
V
F
E
Y
R
Q
A
L
R
V
A
Site 29
T294
V
A
E
E
A
M
F
T
I
R
Q
G
G
R
S
Site 30
S301
T
I
R
Q
G
G
R
S
A
T
E
Y
I
D
E
Site 31
T303
R
Q
G
G
R
S
A
T
E
Y
I
D
E
F
Q
Site 32
Y305
G
G
R
S
A
T
E
Y
I
D
E
F
Q
S
L
Site 33
Y338
L
N
E
E
I
R
H
Y
L
F
R
V
P
Q
P
Site 34
T381
E
A
R
P
R
N
L
T
W
I
D
S
P
A
P
Site 35
S385
R
N
L
T
W
I
D
S
P
A
P
E
R
W
M
Site 36
S395
P
E
R
W
M
V
S
S
W
L
P
S
E
V
H
Site 37
S399
M
V
S
S
W
L
P
S
E
V
H
P
D
I
N
Site 38
Y448
E
K
F
A
Q
E
H
Y
V
E
L
Y
E
K
P
Site 39
Y452
Q
E
H
Y
V
E
L
Y
E
K
P
Y
P
Q
P
Site 40
Y456
V
E
L
Y
E
K
P
Y
P
Q
P
V
Q
S
V
Site 41
S462
P
Y
P
Q
P
V
Q
S
V
D
G
S
L
I
G
Site 42
S466
P
V
Q
S
V
D
G
S
L
I
G
N
E
P
V
Site 43
S561
P
G
L
P
H
P
Y
S
D
L
A
D
V
F
N
Site 44
T576
P
K
E
A
D
D
E
T
S
D
Q
P
S
S
D
Site 45
S577
K
E
A
D
D
E
T
S
D
Q
P
S
S
D
G
Site 46
S581
D
E
T
S
D
Q
P
S
S
D
G
S
D
D
L
Site 47
S582
E
T
S
D
Q
P
S
S
D
G
S
D
D
L
S
Site 48
S585
D
Q
P
S
S
D
G
S
D
D
L
S
E
S
E
Site 49
S589
S
D
G
S
D
D
L
S
E
S
E
P
S
E
L
Site 50
S591
G
S
D
D
L
S
E
S
E
P
S
E
L
Q
Q
Site 51
S594
D
L
S
E
S
E
P
S
E
L
Q
Q
A
G
D
Site 52
S602
E
L
Q
Q
A
G
D
S
D
H
S
E
T
F
Y
Site 53
T607
G
D
S
D
H
S
E
T
F
Y
E
C
P
S
T
Site 54
Y609
S
D
H
S
E
T
F
Y
E
C
P
S
T
A
P
Site 55
T614
T
F
Y
E
C
P
S
T
A
P
W
E
P
V
G
Site 56
Y634
R
A
R
L
Q
E
E
Y
W
D
L
Q
D
M
L
Site 57
Y647
M
L
T
N
R
Q
D
Y
I
Q
M
I
P
E
L
Site 58
T672
T
K
L
E
L
R
G
T
I
V
E
E
S
V
N
Site 59
S677
R
G
T
I
V
E
E
S
V
N
G
H
R
T
E
Site 60
S700
L
E
L
E
E
M
K
S
Y
Q
P
F
A
L
S
Site 61
Y701
E
L
E
E
M
K
S
Y
Q
P
F
A
L
S
P
Site 62
S707
S
Y
Q
P
F
A
L
S
P
D
P
I
I
P
Q
Site 63
Y739
Y
G
Q
E
V
L
I
Y
S
M
S
Q
E
E
H
Site 64
S740
G
Q
E
V
L
I
Y
S
M
S
Q
E
E
H
L
Site 65
S742
E
V
L
I
Y
S
M
S
Q
E
E
H
L
H
H
Site 66
Y763
R
F
R
H
H
N
V
Y
C
S
L
D
K
S
Q
Site 67
T775
K
S
Q
F
H
R
Q
T
V
E
F
L
G
F
V
Site 68
T799
K
N
V
M
T
I
I
T
G
Y
P
T
P
G
S
Site 69
S806
T
G
Y
P
T
P
G
S
K
L
S
L
R
N
F
Site 70
S809
P
T
P
G
S
K
L
S
L
R
N
F
I
E
F
Site 71
S840
P
L
V
R
Q
L
L
S
S
Y
Q
F
Y
W
G
Site 72
Y842
V
R
Q
L
L
S
S
Y
Q
F
Y
W
G
V
E
Site 73
Y845
L
L
S
S
Y
Q
F
Y
W
G
V
E
E
Q
E
Site 74
Y877
P
K
P
Q
N
P
F
Y
L
E
T
G
V
T
G
Site 75
S890
T
G
T
A
L
H
A
S
L
I
Q
I
D
D
Q
Site 76
T898
L
I
Q
I
D
D
Q
T
G
K
R
A
C
C
A
Site 77
Y907
K
R
A
C
C
A
F
Y
S
R
N
I
S
P
I
Site 78
S912
A
F
Y
S
R
N
I
S
P
I
E
V
E
Y
S
Site 79
S919
S
P
I
E
V
E
Y
S
Q
A
E
M
K
I
L
Site 80
S957
L
N
T
E
D
L
A
S
L
N
N
D
R
L
T
Site 81
T964
S
L
N
N
D
R
L
T
V
L
L
P
G
H
W
Site 82
T1010
R
R
A
F
Q
R
N
T
A
A
R
Q
T
L
L
Site 83
T1015
R
N
T
A
A
R
Q
T
L
L
L
A
S
R
G
Site 84
S1028
R
G
F
P
R
D
P
S
T
E
S
G
E
E
E
Site 85
T1029
G
F
P
R
D
P
S
T
E
S
G
E
E
E
N
Site 86
S1124
A
R
P
Q
P
Q
R
S
L
R
L
I
L
D
S
Site 87
S1181
W
Q
R
N
A
L
H
S
Q
A
H
R
G
L
Q
Site 88
T1206
E
F
F
G
V
R
V
T
P
Q
E
G
H
L
P
Site 89
Y1220
P
A
L
R
Q
N
R
Y
L
E
L
H
V
V
G
Site 90
Y1244
L
Q
D
D
L
Q
R
Y
R
Q
C
G
L
H
D
Site 91
S1257
H
D
G
L
Q
D
T
S
Q
D
K
Q
D
N
D
Site 92
S1271
D
V
Q
E
A
P
P
S
H
T
A
A
T
H
P
Site 93
T1276
P
P
S
H
T
A
A
T
H
P
P
R
P
R
H
Site 94
S1302
S
R
L
L
H
I
H
S
A
D
G
Q
L
H
L
Site 95
S1338
L
P
I
P
A
W
E
S
Q
P
R
E
Q
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation