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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTMA
Full Name:
Transmembrane protein 200C
Alias:
Transmembrane protein TTMA;Two transmembrane domain-containing family member A
Type:
Mass (Da):
63928
Number AA:
621
UniProt ID:
A6NKL6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
T
G
G
L
L
R
I
S
A
R
K
Q
D
P
L
Site 2
S22
Q
D
P
L
R
P
P
S
Q
I
P
K
R
K
R
Site 3
T81
Y
W
P
K
A
T
G
T
N
R
E
G
G
K
Q
Site 4
S94
K
Q
L
P
P
A
G
S
S
H
R
V
P
T
T
Site 5
S95
Q
L
P
P
A
G
S
S
H
R
V
P
T
T
A
Site 6
T100
G
S
S
H
R
V
P
T
T
A
N
S
S
S
S
Site 7
T101
S
S
H
R
V
P
T
T
A
N
S
S
S
S
G
Site 8
S104
R
V
P
T
T
A
N
S
S
S
S
G
S
K
N
Site 9
S105
V
P
T
T
A
N
S
S
S
S
G
S
K
N
R
Site 10
S106
P
T
T
A
N
S
S
S
S
G
S
K
N
R
S
Site 11
S107
T
T
A
N
S
S
S
S
G
S
K
N
R
S
R
Site 12
S109
A
N
S
S
S
S
G
S
K
N
R
S
R
S
H
Site 13
S113
S
S
G
S
K
N
R
S
R
S
H
P
R
A
P
Site 14
S115
G
S
K
N
R
S
R
S
H
P
R
A
P
G
G
Site 15
S125
R
A
P
G
G
V
N
S
S
S
A
G
A
P
R
Site 16
S126
A
P
G
G
V
N
S
S
S
A
G
A
P
R
S
Site 17
S127
P
G
G
V
N
S
S
S
A
G
A
P
R
S
T
Site 18
S133
S
S
A
G
A
P
R
S
T
P
P
A
R
A
A
Site 19
T134
S
A
G
A
P
R
S
T
P
P
A
R
A
A
S
Site 20
S141
T
P
P
A
R
A
A
S
P
S
S
S
S
T
S
Site 21
S143
P
A
R
A
A
S
P
S
S
S
S
T
S
V
G
Site 22
S144
A
R
A
A
S
P
S
S
S
S
T
S
V
G
F
Site 23
S145
R
A
A
S
P
S
S
S
S
T
S
V
G
F
F
Site 24
T147
A
S
P
S
S
S
S
T
S
V
G
F
F
F
R
Site 25
S148
S
P
S
S
S
S
T
S
V
G
F
F
F
R
I
Site 26
S157
G
F
F
F
R
I
F
S
G
Y
L
H
S
D
K
Site 27
Y159
F
F
R
I
F
S
G
Y
L
H
S
D
K
L
K
Site 28
T195
H
E
N
R
D
K
K
T
K
I
I
N
L
R
D
Site 29
S235
A
A
A
S
S
S
S
S
A
P
A
A
A
P
P
Site 30
Y253
P
L
N
G
F
L
S
Y
V
Q
S
R
G
L
E
Site 31
S256
G
F
L
S
Y
V
Q
S
R
G
L
E
L
K
P
Site 32
S269
K
P
G
G
C
G
G
S
G
D
A
F
G
A
A
Site 33
S283
A
A
M
L
A
K
G
S
W
P
P
H
P
A
A
Site 34
S292
P
P
H
P
A
A
P
S
G
G
R
P
R
G
A
Site 35
S301
G
R
P
R
G
A
A
S
P
P
D
L
A
S
S
Site 36
S307
A
S
P
P
D
L
A
S
S
P
R
C
P
R
E
Site 37
S308
S
P
P
D
L
A
S
S
P
R
C
P
R
E
P
Site 38
S317
R
C
P
R
E
P
P
S
L
A
E
A
V
Y
S
Site 39
S324
S
L
A
E
A
V
Y
S
V
Y
R
E
R
S
G
Site 40
Y326
A
E
A
V
Y
S
V
Y
R
E
R
S
G
V
A
Site 41
S330
Y
S
V
Y
R
E
R
S
G
V
A
G
S
R
R
Site 42
S335
E
R
S
G
V
A
G
S
R
R
A
A
A
A
T
Site 43
S352
A
A
A
S
S
C
S
S
P
A
P
C
S
P
P
Site 44
S357
C
S
S
P
A
P
C
S
P
P
E
S
W
G
R
Site 45
S361
A
P
C
S
P
P
E
S
W
G
R
Q
S
T
A
Site 46
S366
P
E
S
W
G
R
Q
S
T
A
S
S
F
V
D
Site 47
T367
E
S
W
G
R
Q
S
T
A
S
S
F
V
D
S
Site 48
S369
W
G
R
Q
S
T
A
S
S
F
V
D
S
S
L
Site 49
S370
G
R
Q
S
T
A
S
S
F
V
D
S
S
L
S
Site 50
S400
D
A
E
G
A
S
C
S
W
Q
R
P
P
G
E
Site 51
S410
R
P
P
G
E
R
G
S
Q
E
I
P
R
G
E
Site 52
S421
P
R
G
E
L
D
L
S
M
T
N
L
R
G
A
Site 53
T423
G
E
L
D
L
S
M
T
N
L
R
G
A
E
G
Site 54
S431
N
L
R
G
A
E
G
S
M
R
G
A
R
R
E
Site 55
T461
Q
G
G
R
L
P
R
T
G
R
Y
A
A
L
R
Site 56
S471
Y
A
A
L
R
R
R
S
T
S
G
L
P
D
Y
Site 57
T472
A
A
L
R
R
R
S
T
S
G
L
P
D
Y
R
Site 58
S473
A
L
R
R
R
S
T
S
G
L
P
D
Y
R
A
Site 59
Y478
S
T
S
G
L
P
D
Y
R
A
P
P
S
P
E
Site 60
S483
P
D
Y
R
A
P
P
S
P
E
P
P
P
S
P
Site 61
S489
P
S
P
E
P
P
P
S
P
G
S
A
D
P
D
Site 62
S492
E
P
P
P
S
P
G
S
A
D
P
D
S
S
P
Site 63
S497
P
G
S
A
D
P
D
S
S
P
L
A
K
A
A
Site 64
S498
G
S
A
D
P
D
S
S
P
L
A
K
A
A
S
Site 65
S505
S
P
L
A
K
A
A
S
P
S
P
P
L
R
L
Site 66
S507
L
A
K
A
A
S
P
S
P
P
L
R
L
E
G
Site 67
S515
P
P
L
R
L
E
G
S
P
P
T
R
R
D
S
Site 68
T518
R
L
E
G
S
P
P
T
R
R
D
S
G
S
S
Site 69
S522
S
P
P
T
R
R
D
S
G
S
S
Q
S
D
D
Site 70
S524
P
T
R
R
D
S
G
S
S
Q
S
D
D
P
S
Site 71
S525
T
R
R
D
S
G
S
S
Q
S
D
D
P
S
S
Site 72
S527
R
D
S
G
S
S
Q
S
D
D
P
S
S
S
N
Site 73
S531
S
S
Q
S
D
D
P
S
S
S
N
K
G
Y
T
Site 74
S532
S
Q
S
D
D
P
S
S
S
N
K
G
Y
T
P
Site 75
S533
Q
S
D
D
P
S
S
S
N
K
G
Y
T
P
L
Site 76
Y537
P
S
S
S
N
K
G
Y
T
P
L
R
E
A
G
Site 77
T538
S
S
S
N
K
G
Y
T
P
L
R
E
A
G
T
Site 78
S546
P
L
R
E
A
G
T
S
T
E
S
V
L
D
A
Site 79
S573
P
V
L
G
A
E
Q
S
S
P
E
G
A
S
Q
Site 80
S574
V
L
G
A
E
Q
S
S
P
E
G
A
S
Q
E
Site 81
S579
Q
S
S
P
E
G
A
S
Q
E
P
P
T
A
E
Site 82
T596
Q
P
V
Q
R
Q
F
T
N
K
E
K
L
I
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation