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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
D430041B17
Full Name:
Protein shisa-7
Alias:
LOC729956; Shisa 7
Type:
Mass (Da):
56195
Number AA:
538
UniProt ID:
A6NL88
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S208
V
G
A
K
V
A
F
S
K
A
S
R
A
P
R
Site 2
S211
K
V
A
F
S
K
A
S
R
A
P
R
A
H
R
Site 3
S245
T
R
P
D
R
A
R
S
S
S
L
T
P
G
I
Site 4
S246
R
P
D
R
A
R
S
S
S
L
T
P
G
I
G
Site 5
S247
P
D
R
A
R
S
S
S
L
T
P
G
I
G
G
Site 6
T249
R
A
R
S
S
S
L
T
P
G
I
G
G
P
D
Site 7
S257
P
G
I
G
G
P
D
S
M
P
P
R
T
P
K
Site 8
T262
P
D
S
M
P
P
R
T
P
K
N
L
Y
N
T
Site 9
Y267
P
R
T
P
K
N
L
Y
N
T
V
K
T
P
N
Site 10
T269
T
P
K
N
L
Y
N
T
V
K
T
P
N
L
D
Site 11
T272
N
L
Y
N
T
V
K
T
P
N
L
D
W
R
A
Site 12
S284
W
R
A
L
P
P
P
S
P
S
L
H
Y
S
T
Site 13
S286
A
L
P
P
P
S
P
S
L
H
Y
S
T
L
S
Site 14
Y289
P
P
S
P
S
L
H
Y
S
T
L
S
C
S
R
Site 15
S290
P
S
P
S
L
H
Y
S
T
L
S
C
S
R
S
Site 16
T291
S
P
S
L
H
Y
S
T
L
S
C
S
R
S
F
Site 17
S293
S
L
H
Y
S
T
L
S
C
S
R
S
F
H
N
Site 18
S295
H
Y
S
T
L
S
C
S
R
S
F
H
N
L
S
Site 19
S297
S
T
L
S
C
S
R
S
F
H
N
L
S
H
L
Site 20
S302
S
R
S
F
H
N
L
S
H
L
P
P
S
Y
E
Site 21
S307
N
L
S
H
L
P
P
S
Y
E
A
A
V
K
S
Site 22
Y308
L
S
H
L
P
P
S
Y
E
A
A
V
K
S
E
Site 23
S314
S
Y
E
A
A
V
K
S
E
L
N
R
Y
S
S
Site 24
Y319
V
K
S
E
L
N
R
Y
S
S
L
K
R
L
A
Site 25
S320
K
S
E
L
N
R
Y
S
S
L
K
R
L
A
E
Site 26
S321
S
E
L
N
R
Y
S
S
L
K
R
L
A
E
K
Site 27
Y334
E
K
D
L
D
E
A
Y
L
K
R
R
P
L
E
Site 28
T346
P
L
E
L
P
R
G
T
L
P
L
H
A
L
R
Site 29
T357
H
A
L
R
R
P
G
T
G
G
G
Y
R
M
E
Site 30
S385
P
N
P
R
R
V
M
S
Q
E
H
L
L
G
D
Site 31
Y398
G
D
G
G
R
S
R
Y
E
F
T
L
P
R
A
Site 32
T401
G
R
S
R
Y
E
F
T
L
P
R
A
R
L
V
Site 33
S409
L
P
R
A
R
L
V
S
Q
E
H
L
L
L
S
Site 34
S416
S
Q
E
H
L
L
L
S
S
P
E
A
L
R
Q
Site 35
S417
Q
E
H
L
L
L
S
S
P
E
A
L
R
Q
S
Site 36
S424
S
P
E
A
L
R
Q
S
R
E
H
L
L
S
P
Site 37
S430
Q
S
R
E
H
L
L
S
P
P
R
S
P
A
L
Site 38
S434
H
L
L
S
P
P
R
S
P
A
L
P
P
D
P
Site 39
T442
P
A
L
P
P
D
P
T
A
R
A
S
L
A
A
Site 40
S446
P
D
P
T
A
R
A
S
L
A
A
S
H
S
N
Site 41
T463
L
G
P
G
G
P
P
T
P
L
R
G
L
P
P
Site 42
S472
L
R
G
L
P
P
P
S
S
L
H
A
H
H
H
Site 43
S473
R
G
L
P
P
P
S
S
L
H
A
H
H
H
H
Site 44
S492
S
P
Q
P
A
W
M
S
D
A
G
G
G
G
G
Site 45
T500
D
A
G
G
G
G
G
T
L
A
R
R
P
P
F
Site 46
T512
P
P
F
Q
R
Q
G
T
L
E
Q
L
Q
F
I
Site 47
S532
P
Q
H
L
R
T
A
S
K
N
E
V
T
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation