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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RFPL4A
Full Name:
Ret finger protein-like 4A
Alias:
RING finger protein 210
Type:
Mass (Da):
38513
Number AA:
344
UniProt ID:
A6NLU0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
V
A
K
V
G
G
D
T
L
W
Y
K
S
P
W
Site 2
Y25
V
G
G
D
T
L
W
Y
K
S
P
W
Q
A
A
Site 3
T34
S
P
W
Q
A
A
L
T
P
D
L
S
C
P
Q
Site 4
S38
A
A
L
T
P
D
L
S
C
P
Q
K
Q
L
E
Site 5
T50
Q
L
E
A
R
G
E
T
P
E
G
E
T
F
A
Site 6
T55
G
E
T
P
E
G
E
T
F
A
M
A
E
H
F
Site 7
S94
C
C
L
Q
C
L
N
S
L
Q
K
E
P
D
G
Site 8
Y122
K
D
D
I
K
P
K
Y
K
L
R
A
L
V
S
Site 9
S140
E
L
E
P
K
L
K
S
V
L
T
M
N
P
R
Site 10
T143
P
K
L
K
S
V
L
T
M
N
P
R
M
R
K
Site 11
T156
R
K
F
Q
V
D
M
T
F
D
V
D
T
A
N
Site 12
Y165
D
V
D
T
A
N
N
Y
L
I
I
S
E
D
L
Site 13
S169
A
N
N
Y
L
I
I
S
E
D
L
R
S
F
R
Site 14
S174
I
I
S
E
D
L
R
S
F
R
S
G
D
L
S
Site 15
S177
E
D
L
R
S
F
R
S
G
D
L
S
Q
N
R
Site 16
S181
S
F
R
S
G
D
L
S
Q
N
R
K
E
Q
A
Site 17
T193
E
Q
A
E
R
F
D
T
A
L
C
V
L
G
T
Site 18
T204
V
L
G
T
P
R
F
T
S
G
R
H
Y
W
E
Site 19
S205
L
G
T
P
R
F
T
S
G
R
H
Y
W
E
V
Site 20
Y209
R
F
T
S
G
R
H
Y
W
E
V
D
V
G
T
Site 21
S228
D
V
G
V
C
K
E
S
V
N
R
Q
G
K
I
Site 22
S238
R
Q
G
K
I
E
L
S
S
E
H
G
F
L
T
Site 23
S239
Q
G
K
I
E
L
S
S
E
H
G
F
L
T
V
Site 24
T245
S
S
E
H
G
F
L
T
V
G
C
R
E
G
K
Site 25
S267
P
M
T
P
L
W
V
S
P
Q
L
H
R
V
G
Site 26
Y287
G
M
R
S
I
A
F
Y
N
V
S
D
G
C
H
Site 27
S317
F
F
A
H
K
R
G
S
Q
D
D
Q
S
I
L
Site 28
S322
R
G
S
Q
D
D
Q
S
I
L
S
I
C
S
V
Site 29
S325
Q
D
D
Q
S
I
L
S
I
C
S
V
I
N
P
Site 30
S336
V
I
N
P
S
T
A
S
A
P
V
S
S
E
G
Site 31
S340
S
T
A
S
A
P
V
S
S
E
G
K
_
_
_
Site 32
S341
T
A
S
A
P
V
S
S
E
G
K
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation