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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRAMEF24
Full Name:
Putative PRAME family member 24
Alias:
Type:
Mass (Da):
53669
Number AA:
474
UniProt ID:
A6NMC2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
R
D
Q
A
L
A
I
S
T
M
E
E
L
P
R
Site 2
S45
T
L
F
M
E
A
F
S
R
R
R
C
E
T
L
Site 3
T51
F
S
R
R
R
C
E
T
L
K
T
M
V
Q
A
Site 4
T54
R
R
C
E
T
L
K
T
M
V
Q
A
W
P
F
Site 5
S68
F
T
R
L
P
L
G
S
L
M
K
S
P
H
L
Site 6
S72
P
L
G
S
L
M
K
S
P
H
L
E
S
L
K
Site 7
S77
M
K
S
P
H
L
E
S
L
K
S
V
L
E
G
Site 8
T90
E
G
V
D
V
L
L
T
Q
E
V
R
P
R
Q
Site 9
S98
Q
E
V
R
P
R
Q
S
K
L
Q
V
L
D
L
Site 10
S128
A
S
F
P
E
A
L
S
Q
K
Q
T
A
D
N
Site 11
T132
E
A
L
S
Q
K
Q
T
A
D
N
C
P
G
T
Site 12
T139
T
A
D
N
C
P
G
T
G
R
Q
Q
P
F
M
Site 13
T163
R
T
L
D
E
C
L
T
H
L
L
E
W
G
K
Site 14
S217
V
C
C
P
W
E
L
S
T
L
V
K
F
A
P
Site 15
S260
Q
F
I
A
R
F
T
S
Q
F
L
K
L
D
Y
Site 16
Y267
S
Q
F
L
K
L
D
Y
F
Q
N
L
S
M
H
Site 17
S275
F
Q
N
L
S
M
H
S
V
S
F
L
E
G
H
Site 18
S277
N
L
S
M
H
S
V
S
F
L
E
G
H
L
D
Site 19
T300
S
L
E
M
V
V
M
T
D
C
L
L
S
E
S
Site 20
S307
T
D
C
L
L
S
E
S
D
L
K
H
L
S
W
Site 21
S313
E
S
D
L
K
H
L
S
W
C
P
S
I
R
Q
Site 22
S317
K
H
L
S
W
C
P
S
I
R
Q
L
K
E
L
Site 23
T330
E
L
D
L
R
G
V
T
L
T
H
F
S
P
E
Site 24
T332
D
L
R
G
V
T
L
T
H
F
S
P
E
P
L
Site 25
T349
L
L
E
Q
V
V
A
T
L
Q
T
L
D
L
E
Site 26
S373
S
A
I
L
P
V
L
S
R
C
S
Q
L
S
T
Site 27
S379
L
S
R
C
S
Q
L
S
T
F
S
F
C
G
N
Site 28
T380
S
R
C
S
Q
L
S
T
F
S
F
C
G
N
L
Site 29
S389
S
F
C
G
N
L
I
S
M
A
A
L
E
N
L
Site 30
T400
L
E
N
L
L
R
H
T
V
G
L
S
K
L
S
Site 31
Y411
S
K
L
S
L
E
L
Y
P
A
P
L
E
S
Y
Site 32
T420
A
P
L
E
S
Y
D
T
Q
G
A
L
C
W
G
Site 33
T439
L
G
A
E
L
M
K
T
L
R
D
L
R
Q
P
Site 34
S464
P
R
C
G
I
R
A
S
Y
D
L
E
P
S
H
Site 35
Y465
R
C
G
I
R
A
S
Y
D
L
E
P
S
H
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation