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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM196B
Full Name:
Protein FAM196B
Alias:
Type:
Mass (Da):
59204
Number AA:
535
UniProt ID:
A6NMK8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
L
K
R
N
S
L
E
S
V
E
F
V
K
Q
P
Site 2
S32
K
Q
P
H
H
R
R
S
K
S
Q
Q
V
R
F
Site 3
S34
P
H
H
R
R
S
K
S
Q
Q
V
R
F
K
E
Site 4
T44
V
R
F
K
E
D
G
T
T
K
N
P
T
G
L
Site 5
T45
R
F
K
E
D
G
T
T
K
N
P
T
G
L
A
Site 6
T58
L
A
E
V
D
V
Q
T
P
E
D
P
A
V
M
Site 7
T68
D
P
A
V
M
G
K
T
Q
A
T
R
H
H
L
Site 8
T78
T
R
H
H
L
P
P
T
Y
S
L
S
F
P
R
Site 9
Y79
R
H
H
L
P
P
T
Y
S
L
S
F
P
R
S
Site 10
S80
H
H
L
P
P
T
Y
S
L
S
F
P
R
S
Q
Site 11
S82
L
P
P
T
Y
S
L
S
F
P
R
S
Q
K
A
Site 12
S86
Y
S
L
S
F
P
R
S
Q
K
A
G
G
F
R
Site 13
S100
R
N
I
A
I
Q
T
S
P
S
L
R
K
H
F
Site 14
S102
I
A
I
Q
T
S
P
S
L
R
K
H
F
P
V
Site 15
T116
V
F
K
R
K
R
L
T
A
S
K
S
L
V
E
Site 16
S120
K
R
L
T
A
S
K
S
L
V
E
M
P
T
A
Site 17
T126
K
S
L
V
E
M
P
T
A
S
Q
S
A
I
Q
Site 18
S139
I
Q
V
N
G
N
L
S
E
Q
D
I
V
S
S
Site 19
S146
S
E
Q
D
I
V
S
S
D
L
A
Y
L
R
L
Site 20
S167
G
P
R
R
V
K
V
S
H
A
F
L
P
R
V
Site 21
S179
P
R
V
P
K
V
Q
S
N
G
P
V
S
I
C
Site 22
S194
L
E
A
G
T
W
R
S
L
E
K
A
T
A
A
Site 23
Y209
I
Q
V
P
D
D
I
Y
H
S
P
S
W
E
A
Site 24
S211
V
P
D
D
I
Y
H
S
P
S
W
E
A
R
E
Site 25
S219
P
S
W
E
A
R
E
S
A
L
S
P
D
R
S
Site 26
S222
E
A
R
E
S
A
L
S
P
D
R
S
A
E
V
Site 27
S226
S
A
L
S
P
D
R
S
A
E
V
S
N
S
I
Site 28
S230
P
D
R
S
A
E
V
S
N
S
I
H
P
L
D
Site 29
S232
R
S
A
E
V
S
N
S
I
H
P
L
D
D
T
Site 30
T239
S
I
H
P
L
D
D
T
R
P
G
D
G
R
R
Site 31
T248
P
G
D
G
R
R
V
T
P
L
D
S
E
K
S
Site 32
S252
R
R
V
T
P
L
D
S
E
K
S
T
S
C
L
Site 33
S255
T
P
L
D
S
E
K
S
T
S
C
L
N
A
T
Site 34
T256
P
L
D
S
E
K
S
T
S
C
L
N
A
T
S
Site 35
S257
L
D
S
E
K
S
T
S
C
L
N
A
T
S
V
Site 36
T262
S
T
S
C
L
N
A
T
S
V
A
S
H
T
P
Site 37
S263
T
S
C
L
N
A
T
S
V
A
S
H
T
P
G
Site 38
T268
A
T
S
V
A
S
H
T
P
G
T
E
E
L
K
Site 39
T271
V
A
S
H
T
P
G
T
E
E
L
K
P
E
L
Site 40
S285
L
L
L
P
K
D
N
S
D
D
K
D
L
G
S
Site 41
S292
S
D
D
K
D
L
G
S
L
S
S
Q
S
K
E
Site 42
S294
D
K
D
L
G
S
L
S
S
Q
S
K
E
T
C
Site 43
S295
K
D
L
G
S
L
S
S
Q
S
K
E
T
C
V
Site 44
T300
L
S
S
Q
S
K
E
T
C
V
P
S
S
P
R
Site 45
S304
S
K
E
T
C
V
P
S
S
P
R
T
H
S
S
Site 46
S305
K
E
T
C
V
P
S
S
P
R
T
H
S
S
P
Site 47
T308
C
V
P
S
S
P
R
T
H
S
S
P
S
Q
G
Site 48
S310
P
S
S
P
R
T
H
S
S
P
S
Q
G
S
H
Site 49
S311
S
S
P
R
T
H
S
S
P
S
Q
G
S
H
S
Site 50
S313
P
R
T
H
S
S
P
S
Q
G
S
H
S
Q
P
Site 51
S316
H
S
S
P
S
Q
G
S
H
S
Q
P
A
H
P
Site 52
S318
S
P
S
Q
G
S
H
S
Q
P
A
H
P
G
R
Site 53
S327
P
A
H
P
G
R
A
S
D
C
P
S
S
S
N
Site 54
S331
G
R
A
S
D
C
P
S
S
S
N
N
H
Q
N
Site 55
S332
R
A
S
D
C
P
S
S
S
N
N
H
Q
N
L
Site 56
S333
A
S
D
C
P
S
S
S
N
N
H
Q
N
L
V
Site 57
S341
N
N
H
Q
N
L
V
S
L
K
T
N
S
A
S
Site 58
T344
Q
N
L
V
S
L
K
T
N
S
A
S
K
S
A
Site 59
S346
L
V
S
L
K
T
N
S
A
S
K
S
A
P
G
Site 60
S348
S
L
K
T
N
S
A
S
K
S
A
P
G
C
Q
Site 61
S350
K
T
N
S
A
S
K
S
A
P
G
C
Q
E
Q
Site 62
T367
N
N
P
T
E
S
D
T
L
E
F
P
N
C
P
Site 63
S376
E
F
P
N
C
P
G
S
N
H
L
P
S
S
L
Site 64
S381
P
G
S
N
H
L
P
S
S
L
S
R
S
E
T
Site 65
S382
G
S
N
H
L
P
S
S
L
S
R
S
E
T
K
Site 66
S384
N
H
L
P
S
S
L
S
R
S
E
T
K
L
Q
Site 67
S386
L
P
S
S
L
S
R
S
E
T
K
L
Q
S
N
Site 68
T388
S
S
L
S
R
S
E
T
K
L
Q
S
N
R
E
Site 69
S392
R
S
E
T
K
L
Q
S
N
R
E
I
S
D
I
Site 70
S397
L
Q
S
N
R
E
I
S
D
I
N
Q
I
H
L
Site 71
S418
D
L
Q
G
R
L
Q
S
V
E
E
S
L
H
S
Site 72
S422
R
L
Q
S
V
E
E
S
L
H
S
N
Q
E
K
Site 73
S425
S
V
E
E
S
L
H
S
N
Q
E
K
I
K
V
Site 74
T447
L
E
K
A
R
A
L
T
E
G
R
N
F
Y
R
Site 75
Y453
L
T
E
G
R
N
F
Y
R
T
G
Q
D
L
N
Site 76
T455
E
G
R
N
F
Y
R
T
G
Q
D
L
N
N
C
Site 77
S492
R
F
H
E
V
L
Q
S
L
E
E
A
E
P
V
Site 78
S503
A
E
P
V
E
E
A
S
P
P
P
K
S
P
A
Site 79
S508
E
A
S
P
P
P
K
S
P
A
E
P
P
A
P
Site 80
T524
K
Q
D
L
R
R
K
T
K
K
V
K
K
K
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation