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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM22B
Full Name:
Protein FAM22B
Alias:
Type:
Mass (Da):
93984
Number AA:
878
UniProt ID:
A6NNL0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
V
K
G
P
S
G
R
S
F
C
C
E
Site 2
S10
V
K
G
P
S
G
R
S
F
C
C
E
S
E
G
Site 3
S21
E
S
E
G
Q
F
K
S
C
L
K
R
H
T
P
Site 4
T27
K
S
C
L
K
R
H
T
P
S
L
L
L
P
S
Site 5
S29
C
L
K
R
H
T
P
S
L
L
L
P
S
S
W
Site 6
S34
T
P
S
L
L
L
P
S
S
W
K
G
N
S
G
Site 7
S35
P
S
L
L
L
P
S
S
W
K
G
N
S
G
S
Site 8
S40
P
S
S
W
K
G
N
S
G
S
C
L
M
A
E
Site 9
S42
S
W
K
G
N
S
G
S
C
L
M
A
E
A
L
Site 10
S53
A
E
A
L
H
R
T
S
P
T
P
N
S
C
P
Site 11
T55
A
L
H
R
T
S
P
T
P
N
S
C
P
L
P
Site 12
S58
R
T
S
P
T
P
N
S
C
P
L
P
L
P
L
Site 13
S89
F
S
L
F
Q
L
D
S
G
A
S
G
E
P
G
Site 14
T113
S
Y
C
G
N
C
Q
T
A
V
V
S
A
Q
P
Site 15
S125
A
Q
P
E
G
M
A
S
N
G
A
Y
P
V
L
Site 16
T184
V
L
S
T
F
P
S
T
P
L
V
T
E
Q
D
Site 17
S196
E
Q
D
G
C
G
P
S
G
A
G
A
S
N
V
Site 18
S201
G
P
S
G
A
G
A
S
N
V
F
V
Q
M
R
Site 19
S274
Q
A
C
E
G
G
W
S
Q
G
L
P
L
P
P
Site 20
S294
A
Q
L
P
P
I
V
S
Q
G
N
A
G
P
W
Site 21
S309
P
Q
G
A
H
G
E
S
S
L
A
S
S
Q
A
Site 22
S310
Q
G
A
H
G
E
S
S
L
A
S
S
Q
A
K
Site 23
S313
H
G
E
S
S
L
A
S
S
Q
A
K
A
P
P
Site 24
S314
G
E
S
S
L
A
S
S
Q
A
K
A
P
P
D
Site 25
S323
A
K
A
P
P
D
D
S
C
N
P
R
S
V
Y
Site 26
S328
D
D
S
C
N
P
R
S
V
Y
E
N
F
R
L
Site 27
Y330
S
C
N
P
R
S
V
Y
E
N
F
R
L
W
Q
Site 28
Y339
N
F
R
L
W
Q
H
Y
K
P
L
A
R
R
H
Site 29
S350
A
R
R
H
L
P
Q
S
P
D
T
E
A
L
S
Site 30
T353
H
L
P
Q
S
P
D
T
E
A
L
S
C
F
L
Site 31
T373
S
L
A
R
R
K
P
T
M
T
L
E
E
G
L
Site 32
T375
A
R
R
K
P
T
M
T
L
E
E
G
L
W
R
Site 33
S391
M
R
E
W
Q
H
T
S
N
F
D
R
M
I
F
Site 34
Y399
N
F
D
R
M
I
F
Y
E
M
A
E
K
F
L
Site 35
T433
Q
C
L
P
P
P
A
T
P
R
L
E
P
R
G
Site 36
Y452
E
V
V
K
Q
P
V
Y
L
P
S
K
A
G
P
Site 37
S455
K
Q
P
V
Y
L
P
S
K
A
G
P
K
A
P
Site 38
T476
P
R
P
Q
R
P
V
T
K
A
R
R
P
P
P
Site 39
T491
R
P
H
R
R
A
E
T
K
A
R
L
P
P
P
Site 40
Y520
P
P
E
V
V
Q
E
Y
V
D
I
M
E
E
L
Site 41
T535
L
G
P
S
L
G
A
T
G
E
P
E
K
Q
R
Site 42
T556
Q
P
Q
E
E
D
W
T
P
P
D
P
G
L
L
Site 43
S564
P
P
D
P
G
L
L
S
Y
I
D
K
L
C
S
Site 44
Y565
P
D
P
G
L
L
S
Y
I
D
K
L
C
S
Q
Site 45
S571
S
Y
I
D
K
L
C
S
Q
K
D
F
V
T
K
Site 46
S593
Q
F
L
E
E
L
L
S
P
D
P
Q
M
D
F
Site 47
S604
Q
M
D
F
L
A
L
S
Q
D
L
E
Q
E
E
Site 48
T614
L
E
Q
E
E
G
L
T
L
A
Q
L
V
E
K
Site 49
T640
R
A
A
P
S
R
G
T
A
R
L
D
S
S
S
Site 50
S645
R
G
T
A
R
L
D
S
S
S
S
K
F
A
A
Site 51
S646
G
T
A
R
L
D
S
S
S
S
K
F
A
A
G
Site 52
S647
T
A
R
L
D
S
S
S
S
K
F
A
A
G
Q
Site 53
S648
A
R
L
D
S
S
S
S
K
F
A
A
G
Q
G
Site 54
T677
E
T
C
P
P
Q
M
T
A
R
D
S
Q
G
R
Site 55
S681
P
Q
M
T
A
R
D
S
Q
G
R
G
R
A
H
Site 56
T689
Q
G
R
G
R
A
H
T
G
M
A
R
S
E
D
Site 57
T715
G
L
R
A
A
W
P
T
S
P
P
Q
D
H
R
Site 58
S716
L
R
A
A
W
P
T
S
P
P
Q
D
H
R
P
Site 59
T724
P
P
Q
D
H
R
P
T
C
P
G
V
G
T
K
Site 60
S740
A
L
D
L
P
G
G
S
P
V
R
E
S
H
G
Site 61
S745
G
G
S
P
V
R
E
S
H
G
L
A
Q
G
S
Site 62
S753
H
G
L
A
Q
G
S
S
E
E
E
E
L
P
S
Site 63
S760
S
E
E
E
E
L
P
S
L
A
F
L
L
G
S
Site 64
S767
S
L
A
F
L
L
G
S
Q
H
K
L
L
P
W
Site 65
S784
P
Q
S
P
V
P
A
S
G
L
L
S
P
E
K
Site 66
S788
V
P
A
S
G
L
L
S
P
E
K
W
G
P
Q
Site 67
S800
G
P
Q
G
T
H
Q
S
P
S
A
E
R
R
G
Site 68
S802
Q
G
T
H
Q
S
P
S
A
E
R
R
G
L
N
Site 69
S813
R
G
L
N
L
A
P
S
P
A
N
K
A
K
K
Site 70
S826
K
K
R
P
L
F
G
S
L
S
P
A
E
K
T
Site 71
S828
R
P
L
F
G
S
L
S
P
A
E
K
T
P
Y
Site 72
T833
S
L
S
P
A
E
K
T
P
Y
P
G
P
G
L
Site 73
Y835
S
P
A
E
K
T
P
Y
P
G
P
G
L
R
V
Site 74
S843
P
G
P
G
L
R
V
S
G
E
Q
S
L
T
W
Site 75
S847
L
R
V
S
G
E
Q
S
L
T
W
G
L
G
G
Site 76
T849
V
S
G
E
Q
S
L
T
W
G
L
G
G
P
S
Site 77
S856
T
W
G
L
G
G
P
S
Q
S
Q
K
R
K
G
Site 78
S858
G
L
G
G
P
S
Q
S
Q
K
R
K
G
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation