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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ENO4
Full Name:
Enolase-like protein ENO4
Alias:
Type:
Mass (Da):
68821
Number AA:
628
UniProt ID:
A6NNW6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
G
G
G
R
S
C
G
T
T
R
E
L
Q
K
L
Site 2
T13
G
G
R
S
C
G
T
T
R
E
L
Q
K
L
K
Site 3
Y26
L
K
Q
Q
A
M
E
Y
Y
R
E
N
D
V
P
Site 4
S42
R
L
E
E
L
L
N
S
T
F
Y
L
Q
P
A
Site 5
T43
L
E
E
L
L
N
S
T
F
Y
L
Q
P
A
D
Site 6
Y45
E
L
L
N
S
T
F
Y
L
Q
P
A
D
V
Y
Site 7
Y52
Y
L
Q
P
A
D
V
Y
G
H
L
K
A
N
C
Site 8
T68
S
K
L
A
K
P
P
T
I
C
K
I
V
G
K
Site 9
S130
A
E
E
A
E
R
A
S
A
V
S
T
A
V
Q
Site 10
S133
A
E
R
A
S
A
V
S
T
A
V
Q
W
V
N
Site 11
T134
E
R
A
S
A
V
S
T
A
V
Q
W
V
N
S
Site 12
S168
L
L
R
I
F
F
A
S
K
V
Q
E
D
K
G
Site 13
S182
G
R
K
E
L
E
K
S
L
E
Y
S
T
V
P
Site 14
S186
L
E
K
S
L
E
Y
S
T
V
P
T
P
L
P
Site 15
T187
E
K
S
L
E
Y
S
T
V
P
T
P
L
P
P
Site 16
T190
L
E
Y
S
T
V
P
T
P
L
P
P
V
P
P
Site 17
T205
P
P
P
P
P
P
P
T
K
K
K
G
Q
K
P
Site 18
T217
Q
K
P
G
R
K
D
T
I
T
E
K
P
I
A
Site 19
T219
P
G
R
K
D
T
I
T
E
K
P
I
A
P
A
Site 20
T274
H
N
Q
E
Q
P
T
T
L
S
M
P
L
L
M
Site 21
S290
S
L
V
S
C
G
K
S
S
S
G
K
L
N
L
Site 22
S292
V
S
C
G
K
S
S
S
G
K
L
N
L
M
K
Site 23
S335
I
I
E
M
M
P
P
S
P
P
K
A
E
T
K
Site 24
S348
T
K
K
G
H
D
G
S
K
R
G
Q
Q
Q
I
Site 25
T356
K
R
G
Q
Q
Q
I
T
G
K
M
S
H
L
G
Site 26
Y408
A
G
H
E
L
M
D
Y
N
K
G
K
Y
E
V
Site 27
Y413
M
D
Y
N
K
G
K
Y
E
V
I
M
G
T
Y
Site 28
S452
D
P
F
R
K
E
D
S
E
Q
W
D
S
I
Y
Site 29
S457
E
D
S
E
Q
W
D
S
I
Y
H
A
L
G
S
Site 30
Y459
S
E
Q
W
D
S
I
Y
H
A
L
G
S
R
C
Site 31
T472
R
C
Y
I
I
A
G
T
A
S
K
S
I
S
K
Site 32
S476
I
A
G
T
A
S
K
S
I
S
K
L
L
E
Q
Site 33
S478
G
T
A
S
K
S
I
S
K
L
L
E
Q
G
N
Site 34
S487
L
L
E
Q
G
N
I
S
I
P
K
S
N
G
L
Site 35
S491
G
N
I
S
I
P
K
S
N
G
L
I
I
K
H
Site 36
S505
H
T
N
Q
T
T
M
S
D
L
V
E
I
T
N
Site 37
T521
I
D
S
K
K
H
I
T
V
F
G
S
T
E
G
Site 38
S525
K
H
I
T
V
F
G
S
T
E
G
E
S
S
D
Site 39
S530
F
G
S
T
E
G
E
S
S
D
D
S
L
V
D
Site 40
S531
G
S
T
E
G
E
S
S
D
D
S
L
V
D
L
Site 41
S534
E
G
E
S
S
D
D
S
L
V
D
L
A
V
G
Site 42
T559
L
S
R
G
E
R
V
T
K
Y
N
R
L
L
T
Site 43
Y561
R
G
E
R
V
T
K
Y
N
R
L
L
T
I
E
Site 44
T566
T
K
Y
N
R
L
L
T
I
E
E
E
L
V
Q
Site 45
T584
L
G
F
K
E
E
H
T
F
F
Y
F
N
E
E
Site 46
Y587
K
E
E
H
T
F
F
Y
F
N
E
E
A
E
K
Site 47
T611
A
R
E
P
L
V
P
T
F
P
T
Q
G
V
E
Site 48
S620
P
T
Q
G
V
E
E
S
A
E
T
G
A
S
S
Site 49
T623
G
V
E
E
S
A
E
T
G
A
S
S
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation