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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRIQ3
Full Name:
Leucine-rich repeat and IQ domain-containing protein 3
Alias:
Leucine-rich repeat-containing protein 44
Type:
Mass (Da):
73675
Number AA:
624
UniProt ID:
A6PVS8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
T
V
T
E
E
L
T
S
H
E
E
W
S
H
Y
Site 2
Y19
S
H
E
E
W
S
H
Y
N
E
N
I
R
E
G
Site 3
S42
F
N
G
L
H
L
K
S
M
E
N
L
Q
S
C
Site 4
S48
K
S
M
E
N
L
Q
S
C
I
S
L
R
V
C
Site 5
T90
Q
I
K
S
L
P
N
T
K
F
W
N
G
L
K
Site 6
Y103
L
K
N
L
K
L
L
Y
L
H
D
N
G
F
A
Site 7
S160
A
L
D
H
H
V
I
S
D
E
E
I
I
Q
N
Site 8
T193
C
P
A
L
R
K
G
T
T
Y
E
E
E
I
N
Site 9
Y195
A
L
R
K
G
T
T
Y
E
E
E
I
N
N
I
Site 10
S236
F
L
V
R
K
N
L
S
P
V
F
F
H
K
K
Site 11
Y253
Q
E
K
I
I
R
G
Y
E
A
K
W
I
Y
I
Site 12
Y259
G
Y
E
A
K
W
I
Y
I
T
K
G
Y
E
D
Site 13
Y292
A
Y
W
K
H
N
I
Y
Y
P
V
D
L
K
N
Site 14
Y293
Y
W
K
H
N
I
Y
Y
P
V
D
L
K
N
S
Site 15
S301
P
V
D
L
K
N
S
S
E
H
R
K
H
V
S
Site 16
S309
E
H
R
K
H
V
S
S
I
L
C
E
L
K
P
Site 17
S323
P
K
D
L
G
M
K
S
K
T
S
R
H
L
I
Site 18
T325
D
L
G
M
K
S
K
T
S
R
H
L
I
Q
K
Site 19
S326
L
G
M
K
S
K
T
S
R
H
L
I
Q
K
G
Site 20
S348
V
D
E
K
L
D
T
S
F
R
I
S
V
F
K
Site 21
Y359
S
V
F
K
L
P
I
Y
T
S
G
S
L
K
N
Site 22
S361
F
K
L
P
I
Y
T
S
G
S
L
K
N
N
A
Site 23
S363
L
P
I
Y
T
S
G
S
L
K
N
N
A
V
L
Site 24
Y381
K
Q
H
F
F
P
A
Y
P
Q
P
I
Y
T
T
Site 25
Y386
P
A
Y
P
Q
P
I
Y
T
T
H
P
K
P
I
Site 26
T387
A
Y
P
Q
P
I
Y
T
T
H
P
K
P
I
I
Site 27
T419
R
A
G
M
K
L
R
T
F
S
D
I
D
K
Y
Site 28
S421
G
M
K
L
R
T
F
S
D
I
D
K
Y
Y
T
Site 29
Y426
T
F
S
D
I
D
K
Y
Y
T
E
Q
K
K
Q
Site 30
Y427
F
S
D
I
D
K
Y
Y
T
E
Q
K
K
Q
E
Site 31
T428
S
D
I
D
K
Y
Y
T
E
Q
K
K
Q
E
Y
Site 32
Y466
E
H
L
N
Q
K
K
Y
A
T
Q
K
L
I
E
Site 33
T478
L
I
E
E
N
K
E
T
I
Q
N
S
L
R
Q
Site 34
Y493
V
W
Q
N
R
F
N
Y
L
E
K
A
R
E
R
Site 35
S509
A
L
F
L
K
E
K
S
Q
K
A
S
E
R
L
Site 36
S513
K
E
K
S
Q
K
A
S
E
R
L
L
V
Q
N
Site 37
S549
E
A
V
L
K
E
K
S
L
I
V
K
Q
K
L
Site 38
S574
K
E
M
K
K
V
R
S
Q
E
I
Y
K
R
H
Site 39
Y578
K
V
R
S
Q
E
I
Y
K
R
H
C
E
E
K
Site 40
T605
E
R
L
Q
D
A
K
T
K
V
A
I
V
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation