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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BTBD11
Full Name:
Ankyrin repeat and BTB/POZ domain-containing protein BTBD11
Alias:
BTB (POZ) domain containing 11; BTB/POZ domain-containing protein 11; BTBDB; FLJ33957
Type:
Mass (Da):
120870
Number AA:
UniProt ID:
A6QL63
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
V
R
T
L
E
D
L
T
L
D
S
G
Y
G
G
Site 2
S20
L
E
D
L
T
L
D
S
G
Y
G
G
A
A
D
Site 3
Y22
D
L
T
L
D
S
G
Y
G
G
A
A
D
S
V
Site 4
S28
G
Y
G
G
A
A
D
S
V
R
S
S
N
L
S
Site 5
S35
S
V
R
S
S
N
L
S
L
C
C
S
D
S
H
Site 6
S39
S
N
L
S
L
C
C
S
D
S
H
P
A
S
P
Site 7
S41
L
S
L
C
C
S
D
S
H
P
A
S
P
Y
G
Site 8
S45
C
S
D
S
H
P
A
S
P
Y
G
G
S
C
W
Site 9
S50
P
A
S
P
Y
G
G
S
C
W
P
P
L
A
D
Site 10
S65
S
M
H
S
R
H
N
S
F
D
T
V
N
T
A
Site 11
T68
S
R
H
N
S
F
D
T
V
N
T
A
L
V
E
Site 12
T71
N
S
F
D
T
V
N
T
A
L
V
E
D
S
E
Site 13
S77
N
T
A
L
V
E
D
S
E
G
L
D
C
A
G
Site 14
T100
D
L
D
E
V
P
W
T
L
Q
E
L
E
A
L
Site 15
S151
A
K
E
A
Q
R
L
S
L
R
F
A
K
C
T
Site 16
T158
S
L
R
F
A
K
C
T
K
Y
E
I
Q
S
A
Site 17
Y160
R
F
A
K
C
T
K
Y
E
I
Q
S
A
M
E
Site 18
S193
L
S
L
Y
N
M
S
S
A
G
G
D
R
L
G
Site 19
S204
D
R
L
G
R
G
K
S
A
R
C
G
L
T
F
Site 20
T210
K
S
A
R
C
G
L
T
F
S
V
G
R
V
Y
Site 21
Y217
T
F
S
V
G
R
V
Y
R
W
M
V
D
S
H
Site 22
Y249
E
S
L
F
R
D
I
Y
S
R
V
V
A
S
G
Site 23
S260
V
A
S
G
V
P
R
S
C
S
G
P
G
S
G
Site 24
S262
S
G
V
P
R
S
C
S
G
P
G
S
G
S
G
Site 25
S266
R
S
C
S
G
P
G
S
G
S
G
S
G
P
G
Site 26
S268
C
S
G
P
G
S
G
S
G
S
G
P
G
P
S
Site 27
S270
G
P
G
S
G
S
G
S
G
P
G
P
S
S
G
Site 28
S275
S
G
S
G
P
G
P
S
S
G
P
G
A
A
P
Site 29
S276
G
S
G
P
G
P
S
S
G
P
G
A
A
P
A
Site 30
S305
G
G
A
C
S
A
A
S
S
A
S
G
G
S
S
Site 31
S312
S
S
A
S
G
G
S
S
C
C
A
P
P
A
A
Site 32
T354
T
V
E
T
L
E
H
T
V
N
N
D
S
E
I
Site 33
S386
G
V
L
C
L
P
D
S
L
N
L
H
R
D
P
Site 34
S396
L
H
R
D
P
Q
R
S
N
K
P
G
E
L
P
Site 35
S406
P
G
E
L
P
M
F
S
Q
S
E
L
R
T
I
Site 36
S408
E
L
P
M
F
S
Q
S
E
L
R
T
I
E
Q
Site 37
T412
F
S
Q
S
E
L
R
T
I
E
Q
S
L
L
A
Site 38
S416
E
L
R
T
I
E
Q
S
L
L
A
T
R
V
G
Site 39
S433
A
E
L
S
D
L
V
S
R
A
M
H
H
L
Q
Site 40
T451
A
K
H
H
G
N
G
T
P
L
H
H
K
Q
G
Site 41
Y461
H
H
K
Q
G
A
L
Y
W
E
P
E
A
L
Y
Site 42
S521
A
H
A
G
H
R
R
S
F
S
M
D
S
D
D
Site 43
S523
A
G
H
R
R
S
F
S
M
D
S
D
D
V
R
Site 44
S526
R
R
S
F
S
M
D
S
D
D
V
R
Q
A
A
Site 45
T599
L
G
P
D
G
I
N
T
M
S
E
Q
G
M
T
Site 46
S601
P
D
G
I
N
T
M
S
E
Q
G
M
T
P
L
Site 47
Y610
Q
G
M
T
P
L
M
Y
A
C
V
R
G
D
E
Site 48
T637
L
N
V
E
V
V
S
T
P
H
K
Y
P
S
V
Site 49
Y641
V
V
S
T
P
H
K
Y
P
S
V
H
P
E
T
Site 50
S643
S
T
P
H
K
Y
P
S
V
H
P
E
T
R
H
Site 51
T652
H
P
E
T
R
H
W
T
A
L
T
F
A
V
L
Site 52
S679
A
G
A
K
V
E
G
S
V
E
H
G
E
E
N
Site 53
S688
E
H
G
E
E
N
Y
S
E
T
P
L
Q
L
A
Site 54
T690
G
E
E
N
Y
S
E
T
P
L
Q
L
A
A
A
Site 55
T718
G
A
D
P
L
I
G
T
M
Y
R
N
G
I
S
Site 56
Y720
D
P
L
I
G
T
M
Y
R
N
G
I
S
T
T
Site 57
T726
M
Y
R
N
G
I
S
T
T
P
Q
G
D
M
N
Site 58
T727
Y
R
N
G
I
S
T
T
P
Q
G
D
M
N
S
Site 59
S734
T
P
Q
G
D
M
N
S
F
S
Q
A
A
A
H
Site 60
S736
Q
G
D
M
N
S
F
S
Q
A
A
A
H
G
H
Site 61
S759
A
Q
P
E
K
E
K
S
D
I
L
S
L
E
E
Site 62
S763
K
E
K
S
D
I
L
S
L
E
E
I
L
A
E
Site 63
T777
E
G
T
D
L
A
E
T
A
P
P
P
L
C
A
Site 64
S785
A
P
P
P
L
C
A
S
R
N
S
K
A
K
L
Site 65
S788
P
L
C
A
S
R
N
S
K
A
K
L
R
A
L
Site 66
Y800
R
A
L
R
E
A
M
Y
H
S
A
E
H
G
Y
Site 67
Y807
Y
H
S
A
E
H
G
Y
V
D
V
T
I
D
I
Site 68
T811
E
H
G
Y
V
D
V
T
I
D
I
R
S
I
G
Site 69
T822
R
S
I
G
V
P
W
T
L
H
T
W
L
E
S
Site 70
T851
C
L
L
K
E
F
K
T
I
Q
E
E
E
Y
T
Site 71
T858
T
I
Q
E
E
E
Y
T
E
E
L
V
T
Q
G
Site 72
T890
Q
Q
L
C
V
I
F
T
H
C
Y
G
P
Y
P
Site 73
Y893
C
V
I
F
T
H
C
Y
G
P
Y
P
I
P
K
Site 74
Y896
F
T
H
C
Y
G
P
Y
P
I
P
K
L
T
E
Site 75
T909
T
E
I
K
R
K
Q
T
S
R
L
D
P
H
F
Site 76
S923
F
L
N
N
K
E
M
S
D
V
T
F
L
V
E
Site 77
T926
N
K
E
M
S
D
V
T
F
L
V
E
G
R
P
Site 78
S953
P
R
F
K
A
L
L
S
S
K
P
T
N
D
G
Site 79
T957
A
L
L
S
S
K
P
T
N
D
G
T
C
I
E
Site 80
T961
S
K
P
T
N
D
G
T
C
I
E
I
G
Y
V
Site 81
Y970
I
E
I
G
Y
V
K
Y
S
I
F
Q
L
V
M
Site 82
Y981
Q
L
V
M
Q
Y
L
Y
Y
G
G
P
E
S
L
Site 83
Y982
L
V
M
Q
Y
L
Y
Y
G
G
P
E
S
L
L
Site 84
S987
L
Y
Y
G
G
P
E
S
L
L
I
K
N
N
E
Site 85
Y1031
T
D
N
C
V
D
I
Y
N
H
A
K
F
L
G
Site 86
Y1068
E
A
F
K
Q
L
L
Y
D
K
N
G
E
G
T
Site 87
S1097
R
I
Q
S
I
H
L
S
S
S
K
G
S
V
V
Site 88
S1099
Q
S
I
H
L
S
S
S
K
G
S
V
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation