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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1641
Full Name:
Ankyrin repeat domain-containing protein 36A
Alias:
Type:
Mass (Da):
126773
Number AA:
1120
UniProt ID:
A6QL64
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
V
R
L
R
I
E
L
S
P
Q
K
Q
P
A
E
Site 2
S35
Q
P
A
E
K
A
T
S
D
D
K
D
S
V
S
Site 3
S40
A
T
S
D
D
K
D
S
V
S
N
I
A
T
E
Site 4
S42
S
D
D
K
D
S
V
S
N
I
A
T
E
I
K
Site 5
T46
D
S
V
S
N
I
A
T
E
I
K
E
G
P
I
Site 6
S54
E
I
K
E
G
P
I
S
G
T
V
S
S
Q
K
Site 7
T56
K
E
G
P
I
S
G
T
V
S
S
Q
K
Q
P
Site 8
S58
G
P
I
S
G
T
V
S
S
Q
K
Q
P
A
E
Site 9
S59
P
I
S
G
T
V
S
S
Q
K
Q
P
A
E
K
Site 10
S69
Q
P
A
E
K
A
T
S
D
E
K
D
S
V
S
Site 11
S74
A
T
S
D
E
K
D
S
V
S
N
I
A
T
E
Site 12
S76
S
D
E
K
D
S
V
S
N
I
A
T
E
I
K
Site 13
T80
D
S
V
S
N
I
A
T
E
I
K
E
G
Q
Q
Site 14
S88
E
I
K
E
G
Q
Q
S
G
T
V
S
P
Q
K
Site 15
T90
K
E
G
Q
Q
S
G
T
V
S
P
Q
K
Q
S
Site 16
S92
G
Q
Q
S
G
T
V
S
P
Q
K
Q
S
A
Q
Site 17
S122
R
I
M
G
G
G
K
S
G
T
V
S
S
Q
K
Site 18
T124
M
G
G
G
K
S
G
T
V
S
S
Q
K
Q
P
Site 19
S126
G
G
K
S
G
T
V
S
S
Q
K
Q
P
A
S
Site 20
S127
G
K
S
G
T
V
S
S
Q
K
Q
P
A
S
K
Site 21
S133
S
S
Q
K
Q
P
A
S
K
T
A
S
D
K
T
Site 22
T135
Q
K
Q
P
A
S
K
T
A
S
D
K
T
D
S
Site 23
S137
Q
P
A
S
K
T
A
S
D
K
T
D
S
A
L
Site 24
T140
S
K
T
A
S
D
K
T
D
S
A
L
N
T
A
Site 25
T146
K
T
D
S
A
L
N
T
A
T
E
I
K
D
G
Site 26
T158
K
D
G
L
Q
C
G
T
V
S
S
Q
K
Q
Q
Site 27
S160
G
L
Q
C
G
T
V
S
S
Q
K
Q
Q
A
L
Site 28
S178
T
D
E
E
G
S
V
S
N
I
A
T
E
I
K
Site 29
T182
G
S
V
S
N
I
A
T
E
I
K
D
G
E
K
Site 30
S190
E
I
K
D
G
E
K
S
G
T
V
S
S
Q
K
Site 31
T192
K
D
G
E
K
S
G
T
V
S
S
Q
K
K
P
Site 32
S194
G
E
K
S
G
T
V
S
S
Q
K
K
P
A
L
Site 33
S195
E
K
S
G
T
V
S
S
Q
K
K
P
A
L
K
Site 34
S205
K
P
A
L
K
A
T
S
D
E
K
D
S
F
S
Site 35
S210
A
T
S
D
E
K
D
S
F
S
N
I
T
R
E
Site 36
S212
S
D
E
K
D
S
F
S
N
I
T
R
E
K
K
Site 37
S224
E
K
K
D
G
E
I
S
R
T
V
S
S
Q
K
Site 38
T226
K
D
G
E
I
S
R
T
V
S
S
Q
K
P
P
Site 39
S228
G
E
I
S
R
T
V
S
S
Q
K
P
P
A
L
Site 40
S229
E
I
S
R
T
V
S
S
Q
K
P
P
A
L
K
Site 41
S258
E
K
K
D
G
E
K
S
R
T
V
S
F
E
Q
Site 42
T260
K
D
G
E
K
S
R
T
V
S
F
E
Q
P
P
Site 43
S262
G
E
K
S
R
T
V
S
F
E
Q
P
P
G
L
Site 44
S278
A
T
R
D
E
K
D
S
L
L
N
I
A
R
G
Site 45
T292
G
K
K
D
G
E
K
T
R
R
V
S
S
H
K
Site 46
S296
G
E
K
T
R
R
V
S
S
H
K
Q
P
S
L
Site 47
S297
E
K
T
R
R
V
S
S
H
K
Q
P
S
L
K
Site 48
S302
V
S
S
H
K
Q
P
S
L
K
A
T
S
D
K
Site 49
T306
K
Q
P
S
L
K
A
T
S
D
K
E
D
S
V
Site 50
S312
A
T
S
D
K
E
D
S
V
P
N
M
A
T
E
Site 51
S326
E
T
K
D
E
Q
I
S
G
T
V
S
C
Q
K
Site 52
S330
E
Q
I
S
G
T
V
S
C
Q
K
Q
P
A
L
Site 53
S346
A
T
S
D
K
K
D
S
V
S
N
I
P
T
E
Site 54
S348
S
D
K
K
D
S
V
S
N
I
P
T
E
I
K
Site 55
T352
D
S
V
S
N
I
P
T
E
I
K
D
G
Q
Q
Site 56
S360
E
I
K
D
G
Q
Q
S
G
T
V
S
S
Q
K
Site 57
T362
K
D
G
Q
Q
S
G
T
V
S
S
Q
K
Q
P
Site 58
S364
G
Q
Q
S
G
T
V
S
S
Q
K
Q
P
A
W
Site 59
S380
A
T
S
V
K
K
D
S
V
S
N
I
A
T
E
Site 60
S382
S
V
K
K
D
S
V
S
N
I
A
T
E
I
K
Site 61
T386
D
S
V
S
N
I
A
T
E
I
K
D
G
Q
I
Site 62
T396
K
D
G
Q
I
R
G
T
V
S
S
Q
R
R
P
Site 63
S398
G
Q
I
R
G
T
V
S
S
Q
R
R
P
A
L
Site 64
S399
Q
I
R
G
T
V
S
S
Q
R
R
P
A
L
K
Site 65
T407
Q
R
R
P
A
L
K
T
T
G
D
E
K
D
S
Site 66
S414
T
T
G
D
E
K
D
S
V
S
N
I
A
R
E
Site 67
S416
G
D
E
K
D
S
V
S
N
I
A
R
E
I
K
Site 68
S428
E
I
K
D
G
E
K
S
G
T
V
S
P
Q
K
Site 69
T430
K
D
G
E
K
S
G
T
V
S
P
Q
K
Q
S
Site 70
S432
G
E
K
S
G
T
V
S
P
Q
K
Q
S
A
Q
Site 71
T457
L
N
I
A
T
R
I
T
G
G
W
K
S
G
T
Site 72
S462
R
I
T
G
G
W
K
S
G
T
E
Y
P
E
N
Site 73
T464
T
G
G
W
K
S
G
T
E
Y
P
E
N
L
P
Site 74
Y466
G
W
K
S
G
T
E
Y
P
E
N
L
P
T
L
Site 75
T472
E
Y
P
E
N
L
P
T
L
K
A
T
I
E
N
Site 76
S482
A
T
I
E
N
K
N
S
V
L
N
T
A
T
K
Site 77
T495
T
K
M
K
D
V
Q
T
S
T
P
E
Q
D
L
Site 78
T497
M
K
D
V
Q
T
S
T
P
E
Q
D
L
E
M
Site 79
Y516
E
Q
K
R
L
E
E
Y
E
N
N
Q
P
Q
V
Site 80
S540
L
D
D
I
I
Q
S
S
Q
T
V
S
E
D
G
Site 81
S544
I
Q
S
S
Q
T
V
S
E
D
G
D
S
L
C
Site 82
S610
R
K
L
K
N
K
A
S
V
L
Q
K
R
I
S
Site 83
S617
S
V
L
Q
K
R
I
S
E
K
E
E
I
K
S
Site 84
S624
S
E
K
E
E
I
K
S
Q
L
K
H
E
I
L
Site 85
S639
E
L
E
K
E
L
C
S
L
R
F
A
I
Q
Q
Site 86
T668
V
R
E
K
L
R
I
T
E
E
Q
Y
R
I
E
Site 87
T679
Y
R
I
E
A
D
V
T
K
P
I
K
P
A
L
Site 88
S688
P
I
K
P
A
L
K
S
A
E
V
E
L
K
T
Site 89
T695
S
A
E
V
E
L
K
T
G
G
N
N
S
N
Q
Site 90
S700
L
K
T
G
G
N
N
S
N
Q
V
S
E
T
D
Site 91
S704
G
N
N
S
N
Q
V
S
E
T
D
E
K
E
D
Site 92
T732
R
L
R
L
E
K
D
T
I
K
N
Q
N
L
E
Site 93
Y742
N
Q
N
L
E
K
K
Y
L
K
D
F
E
I
V
Site 94
T770
N
G
E
T
L
A
K
T
I
A
C
Y
S
G
Q
Site 95
T782
S
G
Q
L
A
A
L
T
D
E
N
T
T
L
R
Site 96
T786
A
A
L
T
D
E
N
T
T
L
R
S
K
L
E
Site 97
T787
A
L
T
D
E
N
T
T
L
R
S
K
L
E
K
Site 98
S798
K
L
E
K
Q
R
E
S
R
Q
R
L
E
T
E
Site 99
T804
E
S
R
Q
R
L
E
T
E
M
Q
S
Y
H
C
Site 100
Y809
L
E
T
E
M
Q
S
Y
H
C
R
L
N
A
A
Site 101
S823
A
R
C
D
H
D
Q
S
H
S
S
K
R
D
Q
Site 102
S826
D
H
D
Q
S
H
S
S
K
R
D
Q
E
L
A
Site 103
T837
Q
E
L
A
F
Q
G
T
V
D
K
C
R
H
L
Site 104
S860
L
I
L
S
L
Q
L
S
K
A
E
S
K
S
R
Site 105
S864
L
Q
L
S
K
A
E
S
K
S
R
V
L
K
T
Site 106
S866
L
S
K
A
E
S
K
S
R
V
L
K
T
E
L
Site 107
T871
S
K
S
R
V
L
K
T
E
L
H
Y
T
G
E
Site 108
T876
L
K
T
E
L
H
Y
T
G
E
A
L
K
E
K
Site 109
S899
S
E
L
K
Q
K
Q
S
Q
M
K
D
I
E
K
Site 110
Y912
E
K
M
Y
K
S
G
Y
N
T
M
E
K
C
I
Site 111
T914
M
Y
K
S
G
Y
N
T
M
E
K
C
I
E
K
Site 112
T990
K
M
L
V
N
E
L
T
H
S
K
E
K
E
C
Site 113
S992
L
V
N
E
L
T
H
S
K
E
K
E
C
Q
Y
Site 114
Y999
S
K
E
K
E
C
Q
Y
E
K
E
K
A
E
R
Site 115
S1025
D
D
V
L
N
K
G
S
A
T
K
A
L
L
D
Site 116
S1034
T
K
A
L
L
D
A
S
S
R
H
C
T
Y
L
Site 117
S1035
K
A
L
L
D
A
S
S
R
H
C
T
Y
L
E
Site 118
T1039
D
A
S
S
R
H
C
T
Y
L
E
N
G
M
Q
Site 119
Y1040
A
S
S
R
H
C
T
Y
L
E
N
G
M
Q
D
Site 120
S1048
L
E
N
G
M
Q
D
S
R
K
K
L
D
Q
M
Site 121
S1057
K
K
L
D
Q
M
R
S
Q
F
Q
E
I
Q
D
Site 122
T1067
Q
E
I
Q
D
Q
L
T
A
T
I
R
C
T
K
Site 123
T1069
I
Q
D
Q
L
T
A
T
I
R
C
T
K
E
M
Site 124
T1073
L
T
A
T
I
R
C
T
K
E
M
E
G
D
T
Site 125
S1112
E
K
I
L
Q
H
S
S
L
M
L
Q
V
F
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation