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Updated November 2019
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Protein Info
Short Name:
KIAA0913
Full Name:
Zinc finger SWIM domain-containing protein KIAA0913
Alias:
4832404P21Rik; FLJ34302
Type:
Unknown function
Mass (Da):
197297
Number AA:
1837
UniProt ID:
A7E2V4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
W
E
D
G
E
R
F
S
F
E
D
S
D
R
F
Site 2
S19
E
R
F
S
F
E
D
S
D
R
F
E
E
D
S
Site 3
S26
S
D
R
F
E
E
D
S
L
C
S
F
I
S
E
Site 4
S29
F
E
E
D
S
L
C
S
F
I
S
E
A
E
S
Site 5
S36
S
F
I
S
E
A
E
S
L
C
Q
N
W
R
G
Site 6
S48
W
R
G
W
R
K
Q
S
A
G
P
N
S
P
T
Site 7
S53
K
Q
S
A
G
P
N
S
P
T
G
G
G
G
G
Site 8
T55
S
A
G
P
N
S
P
T
G
G
G
G
G
G
G
Site 9
S63
G
G
G
G
G
G
G
S
G
G
T
R
M
R
D
Site 10
T66
G
G
G
G
S
G
G
T
R
M
R
D
G
L
V
Site 11
Y97
F
E
V
V
E
K
V
Y
P
P
V
P
E
Q
L
Site 12
S112
Q
L
R
I
A
F
W
S
F
P
E
N
E
E
D
Site 13
Y123
N
E
E
D
I
R
L
Y
S
C
L
A
N
G
S
Site 14
S124
E
E
D
I
R
L
Y
S
C
L
A
N
G
S
A
Site 15
S130
Y
S
C
L
A
N
G
S
A
D
E
F
Q
R
G
Site 16
S223
L
R
A
P
V
S
E
S
L
S
R
L
Q
R
D
Site 17
S225
A
P
V
S
E
S
L
S
R
L
Q
R
D
Q
L
Site 18
Y238
Q
L
Q
K
F
A
Q
Y
L
I
S
E
L
P
Q
Site 19
S260
R
L
L
D
E
L
L
S
S
Q
S
T
A
I
N
Site 20
S263
D
E
L
L
S
S
Q
S
T
A
I
N
T
V
C
Site 21
T268
S
Q
S
T
A
I
N
T
V
C
G
A
P
D
P
Site 22
T276
V
C
G
A
P
D
P
T
A
G
P
S
A
S
D
Site 23
S280
P
D
P
T
A
G
P
S
A
S
D
Q
S
T
W
Site 24
S282
P
T
A
G
P
S
A
S
D
Q
S
T
W
Y
L
Site 25
S285
G
P
S
A
S
D
Q
S
T
W
Y
L
D
E
S
Site 26
T286
P
S
A
S
D
Q
S
T
W
Y
L
D
E
S
T
Site 27
Y288
A
S
D
Q
S
T
W
Y
L
D
E
S
T
L
T
Site 28
S292
S
T
W
Y
L
D
E
S
T
L
T
D
N
I
K
Site 29
T293
T
W
Y
L
D
E
S
T
L
T
D
N
I
K
K
Site 30
T295
Y
L
D
E
S
T
L
T
D
N
I
K
K
T
L
Site 31
T301
L
T
D
N
I
K
K
T
L
H
K
F
C
G
P
Site 32
Y320
F
S
D
V
N
S
M
Y
L
S
S
T
E
P
P
Site 33
S322
D
V
N
S
M
Y
L
S
S
T
E
P
P
A
A
Site 34
T324
N
S
M
Y
L
S
S
T
E
P
P
A
A
A
E
Site 35
S363
E
M
F
K
R
R
D
S
N
A
A
P
L
L
E
Site 36
Y387
E
Q
I
T
G
W
W
Y
S
V
R
T
S
A
S
Site 37
S392
W
W
Y
S
V
R
T
S
A
S
H
S
S
A
S
Site 38
S394
Y
S
V
R
T
S
A
S
H
S
S
A
S
G
H
Site 39
S396
V
R
T
S
A
S
H
S
S
A
S
G
H
T
G
Site 40
S397
R
T
S
A
S
H
S
S
A
S
G
H
T
G
R
Site 41
S399
S
A
S
H
S
S
A
S
G
H
T
G
R
S
N
Site 42
S409
T
G
R
S
N
G
Q
S
E
V
A
A
H
A
C
Site 43
S437
A
V
L
D
P
A
L
S
P
Q
R
R
R
E
L
Site 44
T446
Q
R
R
R
E
L
C
T
Q
L
R
Q
W
Q
L
Site 45
T467
K
R
G
Q
H
K
K
T
L
E
R
L
F
P
G
Site 46
Y483
R
P
A
V
E
A
C
Y
F
N
W
E
E
A
Y
Site 47
Y490
Y
F
N
W
E
E
A
Y
P
L
P
G
V
T
Y
Site 48
S498
P
L
P
G
V
T
Y
S
G
T
D
R
K
L
A
Site 49
T500
P
G
V
T
Y
S
G
T
D
R
K
L
A
L
C
Site 50
S514
C
W
A
R
A
L
P
S
R
P
G
A
S
R
S
Site 51
S519
L
P
S
R
P
G
A
S
R
S
G
G
L
E
E
Site 52
S521
S
R
P
G
A
S
R
S
G
G
L
E
E
S
R
Site 53
S527
R
S
G
G
L
E
E
S
R
D
R
P
R
P
L
Site 54
T547
V
R
P
K
E
P
G
T
K
R
K
G
L
G
E
Site 55
S558
G
L
G
E
G
V
P
S
S
Q
R
G
P
R
R
Site 56
S559
L
G
E
G
V
P
S
S
Q
R
G
P
R
R
L
Site 57
S567
Q
R
G
P
R
R
L
S
A
E
G
G
D
K
A
Site 58
S593
K
A
L
G
G
A
G
S
G
S
K
G
S
A
G
Site 59
S595
L
G
G
A
G
S
G
S
K
G
S
A
G
G
G
Site 60
S598
A
G
S
G
S
K
G
S
A
G
G
G
S
K
R
Site 61
S603
K
G
S
A
G
G
G
S
K
R
R
L
S
S
E
Site 62
S608
G
G
S
K
R
R
L
S
S
E
D
S
S
L
E
Site 63
S609
G
S
K
R
R
L
S
S
E
D
S
S
L
E
P
Site 64
S612
R
R
L
S
S
E
D
S
S
L
E
P
D
L
A
Site 65
S613
R
L
S
S
E
D
S
S
L
E
P
D
L
A
E
Site 66
S622
E
P
D
L
A
E
M
S
L
D
D
S
S
L
A
Site 67
S626
A
E
M
S
L
D
D
S
S
L
A
L
G
A
E
Site 68
S627
E
M
S
L
D
D
S
S
L
A
L
G
A
E
A
Site 69
S643
T
F
G
G
F
P
E
S
P
P
P
C
P
L
H
Site 70
S653
P
C
P
L
H
G
G
S
R
G
P
S
T
F
L
Site 71
S657
H
G
G
S
R
G
P
S
T
F
L
P
E
P
P
Site 72
T658
G
G
S
R
G
P
S
T
F
L
P
E
P
P
D
Site 73
T666
F
L
P
E
P
P
D
T
Y
E
E
D
G
G
V
Site 74
Y667
L
P
E
P
P
D
T
Y
E
E
D
G
G
V
Y
Site 75
Y674
Y
E
E
D
G
G
V
Y
F
S
E
G
P
E
P
Site 76
S676
E
D
G
G
V
Y
F
S
E
G
P
E
P
P
T
Site 77
T683
S
E
G
P
E
P
P
T
A
S
V
G
P
P
G
Site 78
S685
G
P
E
P
P
T
A
S
V
G
P
P
G
L
L
Site 79
T698
L
L
P
G
D
V
C
T
Q
D
D
L
P
S
T
Site 80
S704
C
T
Q
D
D
L
P
S
T
D
E
S
G
N
G
Site 81
T705
T
Q
D
D
L
P
S
T
D
E
S
G
N
G
L
Site 82
S708
D
L
P
S
T
D
E
S
G
N
G
L
P
K
T
Site 83
T715
S
G
N
G
L
P
K
T
K
E
A
A
P
A
V
Site 84
Y729
V
G
E
E
D
D
D
Y
Q
A
Y
Y
L
N
A
Site 85
Y732
E
D
D
D
Y
Q
A
Y
Y
L
N
A
Q
D
G
Site 86
Y733
D
D
D
Y
Q
A
Y
Y
L
N
A
Q
D
G
A
Site 87
S787
L
H
A
H
G
Y
S
S
E
A
S
R
L
T
V
Site 88
S790
H
G
Y
S
S
E
A
S
R
L
T
V
E
L
A
Site 89
T793
S
S
E
A
S
R
L
T
V
E
L
A
Q
D
L
Site 90
S822
K
G
K
K
N
K
V
S
T
S
R
Q
T
W
V
Site 91
T827
K
V
S
T
S
R
Q
T
W
V
A
T
N
T
L
Site 92
S845
A
F
L
L
T
V
L
S
E
R
P
E
H
H
N
Site 93
S870
E
L
Q
R
P
P
A
S
T
K
A
L
E
V
K
Site 94
T901
L
G
P
S
E
M
S
T
M
R
C
R
A
E
E
Site 95
T913
A
E
E
L
R
E
G
T
L
C
D
Y
R
P
V
Site 96
Y917
R
E
G
T
L
C
D
Y
R
P
V
L
P
L
M
Site 97
S938
D
V
L
C
A
P
G
S
R
P
P
S
R
N
W
Site 98
S942
A
P
G
S
R
P
P
S
R
N
W
N
S
E
T
Site 99
S947
P
P
S
R
N
W
N
S
E
T
P
G
D
E
E
Site 100
T949
S
R
N
W
N
S
E
T
P
G
D
E
E
L
G
Site 101
T969
A
A
L
G
M
K
T
T
V
S
E
A
E
H
P
Site 102
S971
L
G
M
K
T
T
V
S
E
A
E
H
P
L
L
Site 103
T982
H
P
L
L
C
E
G
T
R
R
E
K
G
D
L
Site 104
S1016
D
K
L
L
D
R
E
S
Q
T
H
K
P
Q
T
Site 105
T1018
L
L
D
R
E
S
Q
T
H
K
P
Q
T
L
S
Site 106
T1023
S
Q
T
H
K
P
Q
T
L
S
S
F
Y
S
S
Site 107
S1025
T
H
K
P
Q
T
L
S
S
F
Y
S
S
S
R
Site 108
S1026
H
K
P
Q
T
L
S
S
F
Y
S
S
S
R
P
Site 109
S1029
Q
T
L
S
S
F
Y
S
S
S
R
P
T
T
A
Site 110
S1030
T
L
S
S
F
Y
S
S
S
R
P
T
T
A
S
Site 111
S1031
L
S
S
F
Y
S
S
S
R
P
T
T
A
S
Q
Site 112
T1034
F
Y
S
S
S
R
P
T
T
A
S
Q
R
S
P
Site 113
T1035
Y
S
S
S
R
P
T
T
A
S
Q
R
S
P
S
Site 114
S1037
S
S
R
P
T
T
A
S
Q
R
S
P
S
K
H
Site 115
S1040
P
T
T
A
S
Q
R
S
P
S
K
H
G
G
P
Site 116
S1042
T
A
S
Q
R
S
P
S
K
H
G
G
P
S
A
Site 117
S1048
P
S
K
H
G
G
P
S
A
P
G
A
L
Q
P
Site 118
T1057
P
G
A
L
Q
P
L
T
S
G
S
A
G
P
A
Site 119
S1058
G
A
L
Q
P
L
T
S
G
S
A
G
P
A
Q
Site 120
S1060
L
Q
P
L
T
S
G
S
A
G
P
A
Q
P
G
Site 121
S1068
A
G
P
A
Q
P
G
S
V
A
G
A
G
P
G
Site 122
S1088
T
E
K
N
V
P
E
S
S
P
H
S
P
C
E
Site 123
S1089
E
K
N
V
P
E
S
S
P
H
S
P
C
E
G
Site 124
S1092
V
P
E
S
S
P
H
S
P
C
E
G
L
P
S
Site 125
S1099
S
P
C
E
G
L
P
S
E
A
A
L
T
P
R
Site 126
T1104
L
P
S
E
A
A
L
T
P
R
P
E
G
K
V
Site 127
S1113
R
P
E
G
K
V
P
S
R
L
A
L
G
S
R
Site 128
S1119
P
S
R
L
A
L
G
S
R
G
G
Y
N
G
R
Site 129
Y1123
A
L
G
S
R
G
G
Y
N
G
R
G
W
G
S
Site 130
S1130
Y
N
G
R
G
W
G
S
P
G
R
P
K
K
K
Site 131
T1139
G
R
P
K
K
K
H
T
G
M
A
S
I
D
S
Site 132
S1143
K
K
H
T
G
M
A
S
I
D
S
S
A
P
E
Site 133
S1146
T
G
M
A
S
I
D
S
S
A
P
E
T
T
S
Site 134
S1147
G
M
A
S
I
D
S
S
A
P
E
T
T
S
D
Site 135
T1151
I
D
S
S
A
P
E
T
T
S
D
S
S
P
T
Site 136
T1152
D
S
S
A
P
E
T
T
S
D
S
S
P
T
L
Site 137
S1153
S
S
A
P
E
T
T
S
D
S
S
P
T
L
S
Site 138
S1155
A
P
E
T
T
S
D
S
S
P
T
L
S
R
R
Site 139
S1156
P
E
T
T
S
D
S
S
P
T
L
S
R
R
P
Site 140
T1158
T
T
S
D
S
S
P
T
L
S
R
R
P
L
R
Site 141
S1160
S
D
S
S
P
T
L
S
R
R
P
L
R
G
G
Site 142
S1172
R
G
G
W
A
P
T
S
W
G
R
G
Q
D
S
Site 143
S1179
S
W
G
R
G
Q
D
S
D
S
I
S
S
S
S
Site 144
S1181
G
R
G
Q
D
S
D
S
I
S
S
S
S
S
D
Site 145
S1183
G
Q
D
S
D
S
I
S
S
S
S
S
D
S
L
Site 146
S1184
Q
D
S
D
S
I
S
S
S
S
S
D
S
L
G
Site 147
S1185
D
S
D
S
I
S
S
S
S
S
D
S
L
G
S
Site 148
S1186
S
D
S
I
S
S
S
S
S
D
S
L
G
S
S
Site 149
S1187
D
S
I
S
S
S
S
S
D
S
L
G
S
S
S
Site 150
S1189
I
S
S
S
S
S
D
S
L
G
S
S
S
S
S
Site 151
S1192
S
S
S
D
S
L
G
S
S
S
S
S
G
S
R
Site 152
S1193
S
S
D
S
L
G
S
S
S
S
S
G
S
R
R
Site 153
S1194
S
D
S
L
G
S
S
S
S
S
G
S
R
R
A
Site 154
S1195
D
S
L
G
S
S
S
S
S
G
S
R
R
A
S
Site 155
S1196
S
L
G
S
S
S
S
S
G
S
R
R
A
S
A
Site 156
S1198
G
S
S
S
S
S
G
S
R
R
A
S
A
S
G
Site 157
S1202
S
S
G
S
R
R
A
S
A
S
G
G
A
R
A
Site 158
S1204
G
S
R
R
A
S
A
S
G
G
A
R
A
K
T
Site 159
T1211
S
G
G
A
R
A
K
T
V
E
V
G
R
Y
K
Site 160
Y1217
K
T
V
E
V
G
R
Y
K
G
R
R
P
E
S
Site 161
S1224
Y
K
G
R
R
P
E
S
H
A
P
H
V
P
N
Site 162
S1234
P
H
V
P
N
Q
P
S
E
A
A
A
H
F
Y
Site 163
S1257
I
K
A
G
G
N
S
S
T
S
I
F
T
H
P
Site 164
S1259
A
G
G
N
S
S
T
S
I
F
T
H
P
S
S
Site 165
T1262
N
S
S
T
S
I
F
T
H
P
S
S
S
G
G
Site 166
S1265
T
S
I
F
T
H
P
S
S
S
G
G
H
Q
G
Site 167
S1266
S
I
F
T
H
P
S
S
S
G
G
H
Q
G
P
Site 168
S1267
I
F
T
H
P
S
S
S
G
G
H
Q
G
P
H
Site 169
S1296
L
G
L
H
N
F
V
S
P
N
W
L
S
R
T
Site 170
S1301
F
V
S
P
N
W
L
S
R
T
Y
S
S
H
V
Site 171
T1303
S
P
N
W
L
S
R
T
Y
S
S
H
V
S
W
Site 172
Y1304
P
N
W
L
S
R
T
Y
S
S
H
V
S
W
I
Site 173
T1335
E
C
W
D
G
H
L
T
P
P
E
V
A
S
L
Site 174
S1341
L
T
P
P
E
V
A
S
L
A
D
R
A
S
R
Site 175
S1347
A
S
L
A
D
R
A
S
R
A
R
D
S
N
M
Site 176
S1352
R
A
S
R
A
R
D
S
N
M
V
R
A
A
A
Site 177
S1432
E
Q
T
A
G
G
S
S
T
A
R
E
G
A
T
Site 178
S1440
T
A
R
E
G
A
T
S
C
S
A
S
G
I
R
Site 179
S1444
G
A
T
S
C
S
A
S
G
I
R
A
G
G
E
Site 180
T1465
E
G
R
G
G
P
G
T
E
P
V
T
V
A
A
Site 181
S1502
P
G
L
G
H
G
H
S
P
G
L
H
P
Y
T
Site 182
Y1508
H
S
P
G
L
H
P
Y
T
A
L
Q
P
H
L
Site 183
T1509
S
P
G
L
H
P
Y
T
A
L
Q
P
H
L
P
Site 184
S1518
L
Q
P
H
L
P
C
S
P
Q
Y
L
T
H
P
Site 185
Y1521
H
L
P
C
S
P
Q
Y
L
T
H
P
A
H
P
Site 186
T1523
P
C
S
P
Q
Y
L
T
H
P
A
H
P
A
H
Site 187
Y1561
P
A
F
L
G
A
Q
Y
P
Y
S
V
T
P
P
Site 188
S1564
L
G
A
Q
Y
P
Y
S
V
T
P
P
S
L
A
Site 189
T1566
A
Q
Y
P
Y
S
V
T
P
P
S
L
A
A
T
Site 190
T1586
V
P
S
M
A
P
I
T
V
H
P
Y
H
T
E
Site 191
S1614
W
G
Q
G
T
V
S
S
V
H
P
A
S
T
F
Site 192
S1641
T
Q
P
S
P
L
V
S
G
G
F
P
P
P
E
Site 193
S1653
P
P
E
E
E
T
H
S
Q
P
V
N
P
H
S
Site 194
S1660
S
Q
P
V
N
P
H
S
L
H
H
L
H
A
A
Site 195
S1691
N
D
H
P
N
N
F
S
R
S
P
P
Y
T
D
Site 196
S1693
H
P
N
N
F
S
R
S
P
P
Y
T
D
D
V
Site 197
Y1696
N
F
S
R
S
P
P
Y
T
D
D
V
K
W
L
Site 198
T1697
F
S
R
S
P
P
Y
T
D
D
V
K
W
L
L
Site 199
S1744
M
E
T
L
Q
R
L
S
P
A
H
A
H
N
H
Site 200
T1780
H
H
R
L
I
H
L
T
P
A
D
Y
D
D
F
Site 201
S1829
K
E
L
W
Q
R
V
S
L
E
M
A
T
F
S
Site 202
T1834
R
V
S
L
E
M
A
T
F
S
P
_
_
_
_
Site 203
S1836
S
L
E
M
A
T
F
S
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation