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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SOBP
Full Name:
Sine oculis-binding protein homolog
Alias:
Jackson circler protein 1
Type:
Mass (Da):
92658
Number AA:
873
UniProt ID:
A7XYQ1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
R
P
P
E
N
K
R
S
R
K
P
A
H
P
V
Site 2
Y48
E
L
L
G
W
Y
G
Y
D
K
V
E
L
K
D
Site 3
S63
G
E
D
I
E
F
R
S
Y
P
T
D
G
E
S
Site 4
Y64
E
D
I
E
F
R
S
Y
P
T
D
G
E
S
R
Site 5
S75
G
E
S
R
Q
H
I
S
V
L
K
E
N
S
L
Site 6
S81
I
S
V
L
K
E
N
S
L
P
K
P
K
L
P
Site 7
S91
K
P
K
L
P
E
D
S
V
I
S
P
Y
N
I
Site 8
S94
L
P
E
D
S
V
I
S
P
Y
N
I
S
T
G
Site 9
Y96
E
D
S
V
I
S
P
Y
N
I
S
T
G
Y
S
Site 10
S103
Y
N
I
S
T
G
Y
S
G
L
A
T
G
N
G
Site 11
T107
T
G
Y
S
G
L
A
T
G
N
G
L
S
D
S
Site 12
S112
L
A
T
G
N
G
L
S
D
S
P
A
G
S
K
Site 13
S114
T
G
N
G
L
S
D
S
P
A
G
S
K
D
H
Site 14
S118
L
S
D
S
P
A
G
S
K
D
H
G
S
V
P
Site 15
S145
P
P
A
E
D
D
V
S
N
V
Q
I
M
C
A
Site 16
S163
K
V
G
I
K
R
Y
S
L
S
M
G
S
E
V
Site 17
S165
G
I
K
R
Y
S
L
S
M
G
S
E
V
K
S
Site 18
S168
R
Y
S
L
S
M
G
S
E
V
K
S
F
C
S
Site 19
S172
S
M
G
S
E
V
K
S
F
C
S
E
K
C
F
Site 20
Y186
F
A
A
C
R
R
A
Y
F
K
R
N
K
A
R
Site 21
T211
Q
Q
H
Y
A
K
E
T
P
R
L
A
F
K
N
Site 22
Y237
H
I
R
H
T
K
E
Y
L
D
F
G
D
G
E
Site 23
Y258
S
A
K
C
L
N
Q
Y
K
M
D
I
F
Y
K
Site 24
Y264
Q
Y
K
M
D
I
F
Y
K
E
T
Q
A
N
L
Site 25
S277
N
L
P
A
G
L
C
S
T
L
H
P
P
M
E
Site 26
T296
G
T
G
V
Q
L
L
T
P
D
S
W
N
I
P
Site 27
S299
V
Q
L
L
T
P
D
S
W
N
I
P
L
T
D
Site 28
T305
D
S
W
N
I
P
L
T
D
A
R
R
K
A
P
Site 29
S313
D
A
R
R
K
A
P
S
P
V
A
T
A
G
Q
Site 30
T317
K
A
P
S
P
V
A
T
A
G
Q
S
Q
G
P
Site 31
S321
P
V
A
T
A
G
Q
S
Q
G
P
G
P
S
A
Site 32
S327
Q
S
Q
G
P
G
P
S
A
S
T
T
V
S
P
Site 33
S329
Q
G
P
G
P
S
A
S
T
T
V
S
P
S
D
Site 34
T331
P
G
P
S
A
S
T
T
V
S
P
S
D
T
A
Site 35
S333
P
S
A
S
T
T
V
S
P
S
D
T
A
N
C
Site 36
S335
A
S
T
T
V
S
P
S
D
T
A
N
C
S
V
Site 37
T337
T
T
V
S
P
S
D
T
A
N
C
S
V
T
K
Site 38
S341
P
S
D
T
A
N
C
S
V
T
K
I
P
T
P
Site 39
T343
D
T
A
N
C
S
V
T
K
I
P
T
P
V
P
Site 40
S352
I
P
T
P
V
P
K
S
I
P
I
S
E
T
P
Site 41
S356
V
P
K
S
I
P
I
S
E
T
P
N
I
P
P
Site 42
T358
K
S
I
P
I
S
E
T
P
N
I
P
P
V
S
Site 43
S365
T
P
N
I
P
P
V
S
V
Q
P
P
A
S
I
Site 44
S382
P
L
G
V
P
P
R
S
P
P
M
V
M
T
N
Site 45
T388
R
S
P
P
M
V
M
T
N
R
G
P
V
P
L
Site 46
S420
R
G
P
P
H
H
A
S
N
P
N
S
P
L
S
Site 47
S424
H
H
A
S
N
P
N
S
P
L
S
N
P
M
L
Site 48
S427
S
N
P
N
S
P
L
S
N
P
M
L
P
G
I
Site 49
T447
G
P
R
N
L
G
P
T
S
S
P
M
H
R
P
Site 50
S448
P
R
N
L
G
P
T
S
S
P
M
H
R
P
M
Site 51
S449
R
N
L
G
P
T
S
S
P
M
H
R
P
M
L
Site 52
S457
P
M
H
R
P
M
L
S
P
H
I
H
P
P
S
Site 53
S464
S
P
H
I
H
P
P
S
T
P
T
M
P
G
N
Site 54
T465
P
H
I
H
P
P
S
T
P
T
M
P
G
N
P
Site 55
S547
P
I
P
I
P
H
V
S
D
S
K
P
P
N
G
Site 56
S549
P
I
P
H
V
S
D
S
K
P
P
N
G
F
S
Site 57
S556
S
K
P
P
N
G
F
S
S
N
G
E
N
F
I
Site 58
S570
I
P
N
A
P
G
D
S
A
A
A
G
G
K
P
Site 59
S578
A
A
A
G
G
K
P
S
G
H
S
L
S
P
R
Site 60
S581
G
G
K
P
S
G
H
S
L
S
P
R
D
S
K
Site 61
S583
K
P
S
G
H
S
L
S
P
R
D
S
K
Q
G
Site 62
S587
H
S
L
S
P
R
D
S
K
Q
G
S
S
K
S
Site 63
S591
P
R
D
S
K
Q
G
S
S
K
S
A
D
S
P
Site 64
S592
R
D
S
K
Q
G
S
S
K
S
A
D
S
P
P
Site 65
S594
S
K
Q
G
S
S
K
S
A
D
S
P
P
G
C
Site 66
S597
G
S
S
K
S
A
D
S
P
P
G
C
S
G
Q
Site 67
T611
Q
A
L
S
L
A
P
T
P
A
E
H
G
R
S
Site 68
S618
T
P
A
E
H
G
R
S
E
V
V
D
L
T
R
Site 69
T624
R
S
E
V
V
D
L
T
R
R
A
G
S
P
P
Site 70
S629
D
L
T
R
R
A
G
S
P
P
G
P
P
G
A
Site 71
T657
Q
D
G
V
I
D
L
T
V
G
H
R
A
R
L
Site 72
S683
V
K
A
E
R
E
P
S
A
A
E
R
R
T
C
Site 73
T689
P
S
A
A
E
R
R
T
C
G
G
C
R
D
G
Site 74
S699
G
C
R
D
G
H
C
S
P
P
A
A
G
D
P
Site 75
S737
A
A
A
E
G
A
K
S
A
E
P
P
P
E
Q
Site 76
S759
A
P
P
K
K
L
L
S
P
E
E
P
A
V
S
Site 77
S766
S
P
E
E
P
A
V
S
E
L
E
S
V
K
E
Site 78
S770
P
A
V
S
E
L
E
S
V
K
E
N
N
C
A
Site 79
S802
A
L
A
G
G
D
K
S
D
P
N
L
N
N
P
Site 80
Y816
P
A
D
E
D
H
A
Y
A
L
R
M
L
P
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation