KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WASH1
Full Name:
WAS protein family homolog 1
Alias:
Protein FAM39E
Type:
Mass (Da):
50504
Number AA:
468
UniProt ID:
A8K0Z3
International Prot ID:
IPI00816771
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
P
V
R
M
Q
H
S
L
A
G
Q
T
Y
A
Site 2
Y39
Q
M
A
D
A
L
Q
Y
L
Q
K
V
S
G
D
Site 3
S44
L
Q
Y
L
Q
K
V
S
G
D
I
F
S
R
I
Site 4
S52
G
D
I
F
S
R
I
S
Q
R
V
E
Q
S
R
Site 5
S60
Q
R
V
E
Q
S
R
S
Q
V
Q
A
I
G
E
Site 6
Y94
K
V
F
S
S
A
K
Y
P
A
P
E
R
L
Q
Site 7
Y103
A
P
E
R
L
Q
E
Y
G
S
I
F
T
G
A
Site 8
S105
E
R
L
Q
E
Y
G
S
I
F
T
G
A
Q
D
Site 9
S119
D
P
G
L
Q
R
R
S
R
H
R
I
Q
S
K
Site 10
S125
R
S
R
H
R
I
Q
S
K
H
R
P
L
D
E
Site 11
S147
K
Y
F
P
V
C
V
S
T
K
P
E
P
E
D
Site 12
S165
E
G
L
G
G
L
P
S
N
I
S
S
V
S
S
Site 13
T178
S
S
L
L
L
F
N
T
T
E
N
L
Y
K
K
Site 14
Y186
T
E
N
L
Y
K
K
Y
V
F
L
D
P
L
A
Site 15
S217
K
L
F
D
A
P
L
S
I
S
K
R
E
Q
L
Site 16
S219
F
D
A
P
L
S
I
S
K
R
E
Q
L
E
Q
Site 17
Y232
E
Q
Q
V
P
E
N
Y
F
Y
V
P
D
L
G
Site 18
Y234
Q
V
P
E
N
Y
F
Y
V
P
D
L
G
Q
V
Site 19
S248
V
P
E
I
D
V
P
S
Y
L
P
D
L
P
G
Site 20
T283
G
T
I
P
E
L
P
T
F
H
T
E
V
A
E
Site 21
T286
P
E
L
P
T
F
H
T
E
V
A
E
P
L
K
Site 22
T302
D
L
Q
D
G
V
L
T
A
P
P
P
P
P
P
Site 23
S329
S
A
S
P
L
P
P
S
T
A
A
P
V
G
Q
Site 24
T330
A
S
P
L
P
P
S
T
A
A
P
V
G
Q
G
Site 25
S344
G
A
R
Q
D
D
G
S
N
S
A
S
P
S
V
Site 26
S346
R
Q
D
D
G
S
N
S
A
S
P
S
V
Q
G
Site 27
S348
D
D
G
S
N
S
A
S
P
S
V
Q
G
A
P
Site 28
S350
G
S
N
S
A
S
P
S
V
Q
G
A
P
R
E
Site 29
S362
P
R
E
V
V
D
P
S
G
G
R
A
T
L
L
Site 30
T367
D
P
S
G
G
R
A
T
L
L
E
S
I
R
Q
Site 31
S385
I
G
K
A
K
L
R
S
V
K
E
R
K
L
E
Site 32
T405
E
Q
E
Q
V
R
A
T
S
Q
G
G
D
L
M
Site 33
S406
Q
E
Q
V
R
A
T
S
Q
G
G
D
L
M
S
Site 34
S413
S
Q
G
G
D
L
M
S
D
L
F
N
K
L
V
Site 35
S447
A
F
A
R
V
S
D
S
I
P
P
L
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation