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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFCAB7
Full Name:
EF-hand calcium-binding domain-containing protein 7
Alias:
Type:
Mass (Da):
71981
Number AA:
629
UniProt ID:
A8K855
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
I
S
P
R
S
D
A
T
F
S
S
Q
Site 2
T10
I
S
P
R
S
D
A
T
F
S
S
Q
K
S
T
Site 3
S12
P
R
S
D
A
T
F
S
S
Q
K
S
T
P
S
Site 4
S13
R
S
D
A
T
F
S
S
Q
K
S
T
P
S
E
Site 5
S16
A
T
F
S
S
Q
K
S
T
P
S
E
S
P
R
Site 6
T17
T
F
S
S
Q
K
S
T
P
S
E
S
P
R
T
Site 7
S19
S
S
Q
K
S
T
P
S
E
S
P
R
T
K
K
Site 8
S21
Q
K
S
T
P
S
E
S
P
R
T
K
K
F
P
Site 9
T24
T
P
S
E
S
P
R
T
K
K
F
P
L
T
E
Site 10
T30
R
T
K
K
F
P
L
T
E
E
E
I
F
Y
M
Site 11
Y36
L
T
E
E
E
I
F
Y
M
N
C
R
A
A
Y
Site 12
Y43
Y
M
N
C
R
A
A
Y
L
T
V
F
K
S
S
Site 13
T45
N
C
R
A
A
Y
L
T
V
F
K
S
S
L
E
Site 14
S56
S
S
L
E
N
I
I
S
K
D
Q
L
Y
L
A
Site 15
S72
Q
H
A
G
R
N
P
S
Q
K
T
I
N
K
Y
Site 16
Y79
S
Q
K
T
I
N
K
Y
W
T
P
Q
T
A
K
Site 17
T81
K
T
I
N
K
Y
W
T
P
Q
T
A
K
L
N
Site 18
S103
L
R
K
E
K
P
T
S
K
A
E
L
L
K
S
Site 19
S110
S
K
A
E
L
L
K
S
F
K
Q
L
D
V
N
Site 20
Y128
C
I
L
H
T
D
L
Y
K
F
L
T
K
R
G
Site 21
T132
T
D
L
Y
K
F
L
T
K
R
G
E
K
M
T
Site 22
T139
T
K
R
G
E
K
M
T
R
E
E
V
N
A
I
Site 23
Y160
N
A
D
G
K
F
D
Y
I
K
F
C
K
L
Y
Site 24
S200
F
G
N
H
I
E
G
S
P
E
R
D
P
S
P
Site 25
S206
G
S
P
E
R
D
P
S
P
V
P
K
P
S
P
Site 26
S212
P
S
P
V
P
K
P
S
P
K
I
T
R
K
T
Site 27
T216
P
K
P
S
P
K
I
T
R
K
T
D
P
E
T
Site 28
T219
S
P
K
I
T
R
K
T
D
P
E
T
F
L
N
Site 29
T223
T
R
K
T
D
P
E
T
F
L
N
K
G
D
T
Site 30
T230
T
F
L
N
K
G
D
T
R
S
S
L
L
S
A
Site 31
S232
L
N
K
G
D
T
R
S
S
L
L
S
A
T
R
Site 32
S233
N
K
G
D
T
R
S
S
L
L
S
A
T
R
K
Site 33
S236
D
T
R
S
S
L
L
S
A
T
R
K
F
K
T
Site 34
T243
S
A
T
R
K
F
K
T
S
V
S
F
T
V
T
Site 35
S244
A
T
R
K
F
K
T
S
V
S
F
T
V
T
M
Site 36
S246
R
K
F
K
T
S
V
S
F
T
V
T
M
G
A
Site 37
T250
T
S
V
S
F
T
V
T
M
G
A
N
G
N
R
Site 38
S259
G
A
N
G
N
R
N
S
K
L
M
E
P
N
L
Site 39
T305
Q
R
S
M
V
Y
L
T
I
K
P
L
N
L
S
Site 40
S312
T
I
K
P
L
N
L
S
Q
V
E
G
K
P
S
Site 41
S319
S
Q
V
E
G
K
P
S
P
W
L
S
V
D
T
Site 42
Y329
L
S
V
D
T
A
L
Y
I
L
K
E
N
E
S
Site 43
S336
Y
I
L
K
E
N
E
S
Q
A
N
L
Q
L
V
Site 44
T372
Y
W
L
I
P
S
T
T
G
C
R
L
R
K
K
Site 45
T384
R
K
K
I
K
P
V
T
D
E
A
Q
L
V
Y
Site 46
T395
Q
L
V
Y
R
D
E
T
G
E
L
F
L
T
K
Site 47
T401
E
T
G
E
L
F
L
T
K
E
F
K
S
T
L
Site 48
T407
L
T
K
E
F
K
S
T
L
S
D
I
F
E
V
Site 49
S409
K
E
F
K
S
T
L
S
D
I
F
E
V
I
D
Site 50
S424
L
D
G
N
G
L
L
S
L
E
E
Y
N
F
F
Site 51
Y428
G
L
L
S
L
E
E
Y
N
F
F
E
L
R
T
Site 52
S436
N
F
F
E
L
R
T
S
G
E
K
C
D
E
D
Site 53
T454
V
C
R
E
N
F
D
T
K
R
N
E
L
T
R
Site 54
Y508
C
P
F
V
I
D
I
Y
A
E
K
C
K
P
K
Site 55
S535
L
E
K
A
I
C
K
S
V
L
S
N
G
D
A
Site 56
Y548
D
A
K
V
M
D
G
Y
E
N
I
I
V
H
T
Site 57
S570
T
S
V
I
E
N
K
S
D
E
K
V
I
I
H
Site 58
S579
E
K
V
I
I
H
I
S
N
E
L
S
K
N
C
Site 59
Y621
N
E
R
Q
E
W
I
Y
Y
C
I
Y
S
L
I
Site 60
Y622
E
R
Q
E
W
I
Y
Y
C
I
Y
S
L
I
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation