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Updated November 2019
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Protein Info
Short Name:
SFI1
Full Name:
Protein SFI1 homolog
Alias:
Type:
Mass (Da):
147664
Number AA:
1242
UniProt ID:
A8K8P3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
E
K
K
V
D
S
R
Y
F
K
D
G
A
V
K
Site 2
Y42
D
G
A
V
K
K
P
Y
S
A
K
T
L
S
N
Site 3
S43
G
A
V
K
K
P
Y
S
A
K
T
L
S
N
K
Site 4
T46
K
K
P
Y
S
A
K
T
L
S
N
K
K
S
S
Site 5
S48
P
Y
S
A
K
T
L
S
N
K
K
S
S
A
S
Site 6
S52
K
T
L
S
N
K
K
S
S
A
S
F
G
I
R
Site 7
S55
S
N
K
K
S
S
A
S
F
G
I
R
R
E
L
Site 8
S64
G
I
R
R
E
L
P
S
T
S
H
L
V
Q
Y
Site 9
T65
I
R
R
E
L
P
S
T
S
H
L
V
Q
Y
R
Site 10
S66
R
R
E
L
P
S
T
S
H
L
V
Q
Y
R
G
Site 11
T74
H
L
V
Q
Y
R
G
T
H
T
C
T
R
Q
G
Site 12
T76
V
Q
Y
R
G
T
H
T
C
T
R
Q
G
R
L
Site 13
Y115
F
P
S
K
A
R
F
Y
Y
E
Q
R
L
L
R
Site 14
Y116
P
S
K
A
R
F
Y
Y
E
Q
R
L
L
R
K
Site 15
Y149
C
V
R
A
D
C
H
Y
R
Y
Y
L
Y
N
L
Site 16
Y152
A
D
C
H
Y
R
Y
Y
L
Y
N
L
M
F
Q
Site 17
Y154
C
H
Y
R
Y
Y
L
Y
N
L
M
F
Q
T
W
Site 18
Y164
M
F
Q
T
W
K
T
Y
V
R
Q
Q
Q
E
M
Site 19
Y175
Q
Q
E
M
R
N
K
Y
I
R
A
E
V
H
D
Site 20
Y197
A
W
K
S
W
L
I
Y
V
V
V
R
R
T
K
Site 21
T203
I
Y
V
V
V
R
R
T
K
L
Q
M
Q
T
T
Site 22
S237
R
L
G
Q
V
R
V
S
R
A
L
H
A
S
A
Site 23
S243
V
S
R
A
L
H
A
S
A
L
K
H
R
A
L
Site 24
S251
A
L
K
H
R
A
L
S
L
Q
V
Q
A
W
S
Site 25
S258
S
L
Q
V
Q
A
W
S
Q
W
R
E
Q
L
L
Site 26
Y266
Q
W
R
E
Q
L
L
Y
V
Q
K
E
K
Q
K
Site 27
S335
Q
A
W
E
R
R
E
S
L
Y
A
H
H
A
Q
Site 28
Y337
W
E
R
R
E
S
L
Y
A
H
H
A
Q
V
E
Site 29
Y386
H
H
R
H
S
Q
L
Y
F
C
F
R
A
L
K
Site 30
T397
R
A
L
K
D
N
V
T
H
A
H
L
Q
Q
I
Site 31
T464
I
E
L
W
L
Q
Y
T
Q
K
R
R
Y
K
Q
Site 32
Y469
Q
Y
T
Q
K
R
R
Y
K
Q
L
L
Q
A
R
Site 33
S507
R
H
Q
E
N
V
L
S
A
R
A
T
R
F
H
Site 34
T511
N
V
L
S
A
R
A
T
R
F
H
R
E
T
L
Site 35
T517
A
T
R
F
H
R
E
T
L
E
K
Q
V
F
S
Site 36
S595
A
F
C
L
W
R
E
S
A
Q
G
L
R
T
E
Site 37
T601
E
S
A
Q
G
L
R
T
E
R
T
G
R
V
R
Site 38
T604
Q
G
L
R
T
E
R
T
G
R
V
R
A
A
E
Site 39
S649
A
D
L
H
H
Q
H
S
V
L
H
R
A
L
Q
Site 40
T660
R
A
L
Q
A
W
V
T
Y
Q
G
R
V
R
S
Site 41
S667
T
Y
Q
G
R
V
R
S
I
L
R
E
V
A
A
Site 42
S677
R
E
V
A
A
R
E
S
Q
H
N
R
Q
L
L
Site 43
T695
L
R
R
W
K
E
N
T
M
A
R
V
D
E
A
Site 44
T705
R
V
D
E
A
K
K
T
F
Q
A
S
T
H
Y
Site 45
T710
K
K
T
F
Q
A
S
T
H
Y
R
R
T
I
C
Site 46
Y712
T
F
Q
A
S
T
H
Y
R
R
T
I
C
S
K
Site 47
T715
A
S
T
H
Y
R
R
T
I
C
S
K
V
L
V
Site 48
Y733
E
A
V
S
V
Q
M
Y
Y
R
Q
Q
E
D
C
Site 49
Y734
A
V
S
V
Q
M
Y
Y
R
Q
Q
E
D
C
A
Site 50
S811
K
R
L
L
H
R
Q
S
T
Q
L
L
A
Q
R
Site 51
T812
R
L
L
H
R
Q
S
T
Q
L
L
A
Q
R
L
Site 52
S820
Q
L
L
A
Q
R
L
S
R
T
C
F
R
Q
W
Site 53
S899
R
L
L
R
F
A
A
S
M
K
A
S
R
Q
Q
Site 54
S903
F
A
A
S
M
K
A
S
R
Q
Q
L
Q
A
Q
Site 55
T928
R
A
V
R
R
C
A
T
L
W
K
Q
K
V
L
Site 56
T954
I
A
P
S
R
K
V
T
F
E
G
P
L
L
N
Site 57
T971
A
A
G
A
G
D
G
T
L
E
T
K
R
P
Q
Site 58
T974
A
G
D
G
T
L
E
T
K
R
P
Q
A
S
R
Site 59
S1004
L
E
L
N
T
A
H
S
A
R
K
Q
P
R
R
Site 60
S1021
F
L
L
E
P
A
Q
S
Q
R
P
Q
K
P
Q
Site 61
S1065
S
P
L
P
G
A
L
S
S
A
P
G
P
K
Q
Site 62
S1066
P
L
P
G
A
L
S
S
A
P
G
P
K
Q
P
Site 63
T1075
P
G
P
K
Q
P
P
T
A
S
T
G
P
E
L
Site 64
S1077
P
K
Q
P
P
T
A
S
T
G
P
E
L
L
L
Site 65
S1102
A
A
A
P
A
R
V
S
A
Q
R
A
T
P
R
Site 66
T1107
R
V
S
A
Q
R
A
T
P
R
D
K
P
P
V
Site 67
S1116
R
D
K
P
P
V
P
S
S
L
A
S
V
P
D
Site 68
S1117
D
K
P
P
V
P
S
S
L
A
S
V
P
D
P
Site 69
S1142
T
R
A
G
P
G
L
S
T
A
G
S
L
D
L
Site 70
S1172
T
T
K
Q
N
L
W
S
C
R
R
Q
A
S
S
Site 71
S1178
W
S
C
R
R
Q
A
S
S
L
R
R
W
L
E
Site 72
S1179
S
C
R
R
Q
A
S
S
L
R
R
W
L
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation