KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZBBX
Full Name:
Zinc finger B-box domain-containing protein 1
Alias:
Type:
Mass (Da):
91426
Number AA:
800
UniProt ID:
A8MT70
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S51
K
K
L
Q
E
F
R
S
T
R
N
K
E
K
E
Site 2
T52
K
L
Q
E
F
R
S
T
R
N
K
E
K
E
D
Site 3
S62
K
E
K
E
D
R
E
S
S
E
Y
Y
W
K
S
Site 4
S63
E
K
E
D
R
E
S
S
E
Y
Y
W
K
S
G
Site 5
Y65
E
D
R
E
S
S
E
Y
Y
W
K
S
G
K
V
Site 6
Y66
D
R
E
S
S
E
Y
Y
W
K
S
G
K
V
G
Site 7
S69
S
S
E
Y
Y
W
K
S
G
K
V
G
K
L
V
Site 8
Y80
G
K
L
V
N
Q
S
Y
M
M
S
Q
N
K
G
Site 9
S122
N
Y
K
M
A
N
S
S
E
C
E
K
P
K
I
Site 10
Y153
C
L
E
C
G
E
D
Y
C
S
G
C
F
A
K
Site 11
T173
A
L
K
L
H
R
T
T
L
L
Q
A
K
S
Q
Site 12
S207
E
P
K
E
E
N
N
S
T
K
E
T
S
K
I
Site 13
T208
P
K
E
E
N
N
S
T
K
E
T
S
K
I
Q
Site 14
S220
K
I
Q
H
K
P
K
S
V
L
L
Q
R
S
S
Site 15
S226
K
S
V
L
L
Q
R
S
S
S
E
V
E
I
T
Site 16
S227
S
V
L
L
Q
R
S
S
S
E
V
E
I
T
T
Site 17
T233
S
S
S
E
V
E
I
T
T
M
K
R
A
Q
R
Site 18
T241
T
M
K
R
A
Q
R
T
K
P
R
K
S
L
L
Site 19
S246
Q
R
T
K
P
R
K
S
L
L
C
E
G
S
F
Site 20
S252
K
S
L
L
C
E
G
S
F
D
E
E
A
S
A
Site 21
S258
G
S
F
D
E
E
A
S
A
Q
S
F
Q
E
V
Site 22
S261
D
E
E
A
S
A
Q
S
F
Q
E
V
L
S
Q
Site 23
S267
Q
S
F
Q
E
V
L
S
Q
W
R
T
G
N
H
Site 24
T271
E
V
L
S
Q
W
R
T
G
N
H
D
D
N
K
Site 25
S289
L
H
A
A
V
K
D
S
L
E
E
C
E
V
Q
Site 26
S316
E
L
K
E
D
I
L
S
Y
M
E
K
L
W
L
Site 27
Y317
L
K
E
D
I
L
S
Y
M
E
K
L
W
L
K
Site 28
T329
W
L
K
K
H
R
R
T
P
Q
E
Q
L
F
K
Site 29
T341
L
F
K
M
L
P
D
T
F
P
H
P
H
E
T
Site 30
S355
T
T
G
D
A
Q
C
S
Q
N
E
N
D
E
D
Site 31
S363
Q
N
E
N
D
E
D
S
D
G
E
E
T
K
V
Site 32
T399
K
I
V
E
L
D
D
T
Y
E
E
E
F
E
E
Site 33
Y400
I
V
E
L
D
D
T
Y
E
E
E
F
E
E
A
Site 34
S422
V
K
L
A
D
A
D
S
Q
R
S
C
A
F
H
Site 35
S463
L
N
L
C
L
R
N
S
S
T
Y
Y
K
D
N
Site 36
S464
N
L
C
L
R
N
S
S
T
Y
Y
K
D
N
S
Site 37
T465
L
C
L
R
N
S
S
T
Y
Y
K
D
N
S
K
Site 38
Y466
C
L
R
N
S
S
T
Y
Y
K
D
N
S
K
A
Site 39
Y467
L
R
N
S
S
T
Y
Y
K
D
N
S
K
A
E
Site 40
S471
S
T
Y
Y
K
D
N
S
K
A
E
T
S
N
T
Site 41
T478
S
K
A
E
T
S
N
T
D
F
D
N
I
V
D
Site 42
Y489
N
I
V
D
P
D
V
Y
S
S
D
I
E
K
I
Site 43
S490
I
V
D
P
D
V
Y
S
S
D
I
E
K
I
E
Site 44
S491
V
D
P
D
V
Y
S
S
D
I
E
K
I
E
E
Site 45
S499
D
I
E
K
I
E
E
S
T
S
F
E
R
N
L
Site 46
S501
E
K
I
E
E
S
T
S
F
E
R
N
L
K
E
Site 47
S515
E
K
N
I
G
L
E
S
N
Q
K
S
D
D
S
Site 48
S519
G
L
E
S
N
Q
K
S
D
D
S
C
V
S
L
Site 49
S522
S
N
Q
K
S
D
D
S
C
V
S
L
E
S
K
Site 50
S525
K
S
D
D
S
C
V
S
L
E
S
K
D
T
L
Site 51
S528
D
S
C
V
S
L
E
S
K
D
T
L
L
G
R
Site 52
T531
V
S
L
E
S
K
D
T
L
L
G
R
D
L
E
Site 53
S547
A
P
I
E
E
K
L
S
Q
D
I
K
E
S
L
Site 54
S553
L
S
Q
D
I
K
E
S
L
E
L
S
N
L
Y
Site 55
S557
I
K
E
S
L
E
L
S
N
L
Y
K
R
P
S
Site 56
Y560
S
L
E
L
S
N
L
Y
K
R
P
S
F
E
E
Site 57
S564
S
N
L
Y
K
R
P
S
F
E
E
S
K
T
T
Site 58
S568
K
R
P
S
F
E
E
S
K
T
T
K
S
S
L
Site 59
T570
P
S
F
E
E
S
K
T
T
K
S
S
L
L
L
Site 60
T571
S
F
E
E
S
K
T
T
K
S
S
L
L
L
Q
Site 61
S574
E
S
K
T
T
K
S
S
L
L
L
Q
E
I
A
Site 62
S584
L
Q
E
I
A
C
R
S
K
P
I
T
K
Q
Y
Site 63
T588
A
C
R
S
K
P
I
T
K
Q
Y
Q
G
L
E
Site 64
Y591
S
K
P
I
T
K
Q
Y
Q
G
L
E
R
F
F
Site 65
T602
E
R
F
F
I
F
D
T
N
E
R
L
N
L
L
Site 66
S611
E
R
L
N
L
L
P
S
H
R
L
E
C
N
N
Site 67
S619
H
R
L
E
C
N
N
S
S
T
R
I
T
L
A
Site 68
S620
R
L
E
C
N
N
S
S
T
R
I
T
L
A
G
Site 69
T624
N
N
S
S
T
R
I
T
L
A
G
Q
K
S
Q
Site 70
S630
I
T
L
A
G
Q
K
S
Q
R
P
S
T
A
N
Site 71
S634
G
Q
K
S
Q
R
P
S
T
A
N
F
P
L
S
Site 72
T635
Q
K
S
Q
R
P
S
T
A
N
F
P
L
S
N
Site 73
S641
S
T
A
N
F
P
L
S
N
S
V
K
E
S
S
Site 74
S643
A
N
F
P
L
S
N
S
V
K
E
S
S
S
C
Site 75
S647
L
S
N
S
V
K
E
S
S
S
C
L
S
S
S
Site 76
S648
S
N
S
V
K
E
S
S
S
C
L
S
S
S
H
Site 77
S649
N
S
V
K
E
S
S
S
C
L
S
S
S
H
P
Site 78
S652
K
E
S
S
S
C
L
S
S
S
H
P
R
S
R
Site 79
S653
E
S
S
S
C
L
S
S
S
H
P
R
S
R
S
Site 80
S654
S
S
S
C
L
S
S
S
H
P
R
S
R
S
A
Site 81
S658
L
S
S
S
H
P
R
S
R
S
A
A
A
Q
S
Site 82
S660
S
S
H
P
R
S
R
S
A
A
A
Q
S
S
S
Site 83
S665
S
R
S
A
A
A
Q
S
S
S
R
A
A
S
E
Site 84
S666
R
S
A
A
A
Q
S
S
S
R
A
A
S
E
I
Site 85
S667
S
A
A
A
Q
S
S
S
R
A
A
S
E
I
S
Site 86
S671
Q
S
S
S
R
A
A
S
E
I
S
E
I
E
Y
Site 87
Y678
S
E
I
S
E
I
E
Y
I
D
I
T
D
Q
N
Site 88
T682
E
I
E
Y
I
D
I
T
D
Q
N
E
L
S
L
Site 89
S688
I
T
D
Q
N
E
L
S
L
D
D
T
T
D
Q
Site 90
T692
N
E
L
S
L
D
D
T
T
D
Q
H
T
L
D
Site 91
T693
E
L
S
L
D
D
T
T
D
Q
H
T
L
D
N
Site 92
S710
K
E
L
Q
V
L
R
S
L
A
D
T
S
E
K
Site 93
T714
V
L
R
S
L
A
D
T
S
E
K
L
Y
S
L
Site 94
S715
L
R
S
L
A
D
T
S
E
K
L
Y
S
L
T
Site 95
Y719
A
D
T
S
E
K
L
Y
S
L
T
S
E
E
F
Site 96
S720
D
T
S
E
K
L
Y
S
L
T
S
E
E
F
P
Site 97
T722
S
E
K
L
Y
S
L
T
S
E
E
F
P
D
F
Site 98
S723
E
K
L
Y
S
L
T
S
E
E
F
P
D
F
S
Site 99
S730
S
E
E
F
P
D
F
S
S
Q
S
L
N
I
S
Site 100
S731
E
E
F
P
D
F
S
S
Q
S
L
N
I
S
Q
Site 101
S733
F
P
D
F
S
S
Q
S
L
N
I
S
Q
I
S
Site 102
S737
S
S
Q
S
L
N
I
S
Q
I
S
T
D
F
L
Site 103
T741
L
N
I
S
Q
I
S
T
D
F
L
K
T
S
H
Site 104
S747
S
T
D
F
L
K
T
S
H
V
R
G
P
C
G
Site 105
S759
P
C
G
V
E
E
L
S
C
S
G
R
D
T
K
Site 106
S761
G
V
E
E
L
S
C
S
G
R
D
T
K
I
Q
Site 107
T765
L
S
C
S
G
R
D
T
K
I
Q
S
L
L
S
Site 108
S769
G
R
D
T
K
I
Q
S
L
L
S
L
S
E
S
Site 109
S772
T
K
I
Q
S
L
L
S
L
S
E
S
S
T
D
Site 110
S774
I
Q
S
L
L
S
L
S
E
S
S
T
D
E
E
Site 111
S776
S
L
L
S
L
S
E
S
S
T
D
E
E
E
E
Site 112
T778
L
S
L
S
E
S
S
T
D
E
E
E
E
D
F
Site 113
T793
L
N
K
Q
H
V
I
T
L
P
W
S
K
S
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation