KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FOXI3
Full Name:
Forkhead box protein I3
Alias:
Type:
Mass (Da):
43326
Number AA:
420
UniProt ID:
A8MTJ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
C
G
D
N
F
G
V
Y
S
Q
P
G
L
P
P
Site 2
S13
G
D
N
F
G
V
Y
S
Q
P
G
L
P
P
P
Site 3
Y37
P
P
A
A
R
A
P
Y
G
L
A
D
Y
A
A
Site 4
Y53
P
A
A
A
A
N
P
Y
L
W
L
N
G
P
G
Site 5
T101
Q
P
P
P
A
A
G
T
F
G
C
S
Q
R
P
Site 6
S105
A
A
G
T
F
G
C
S
Q
R
P
F
A
Q
P
Site 7
S133
P
G
E
L
G
W
L
S
M
A
S
R
E
D
L
Site 8
T167
S
A
P
E
R
K
L
T
L
S
H
I
Y
Q
F
Site 9
S169
P
E
R
K
L
T
L
S
H
I
Y
Q
F
V
A
Site 10
Y182
V
A
D
S
F
P
F
Y
Q
R
S
K
A
G
W
Site 11
S192
S
K
A
G
W
Q
N
S
I
R
H
N
L
S
L
Site 12
S198
N
S
I
R
H
N
L
S
L
N
D
C
F
K
K
Site 13
Y218
D
D
P
G
K
G
N
Y
W
T
L
D
P
N
C
Site 14
S242
R
R
K
R
K
R
R
S
E
A
S
N
G
S
T
Site 15
S245
R
K
R
R
S
E
A
S
N
G
S
T
V
A
A
Site 16
S248
R
S
E
A
S
N
G
S
T
V
A
A
G
T
S
Site 17
T249
S
E
A
S
N
G
S
T
V
A
A
G
T
S
K
Site 18
S255
S
T
V
A
A
G
T
S
K
S
E
E
G
L
S
Site 19
S257
V
A
A
G
T
S
K
S
E
E
G
L
S
S
G
Site 20
S262
S
K
S
E
E
G
L
S
S
G
L
G
S
G
V
Site 21
S263
K
S
E
E
G
L
S
S
G
L
G
S
G
V
G
Site 22
S267
G
L
S
S
G
L
G
S
G
V
G
G
K
P
E
Site 23
S277
G
G
K
P
E
E
E
S
P
S
T
L
L
R
P
Site 24
S279
K
P
E
E
E
S
P
S
T
L
L
R
P
S
H
Site 25
T280
P
E
E
E
S
P
S
T
L
L
R
P
S
H
S
Site 26
S285
P
S
T
L
L
R
P
S
H
S
P
E
P
P
E
Site 27
S287
T
L
L
R
P
S
H
S
P
E
P
P
E
G
T
Site 28
S296
E
P
P
E
G
T
K
S
T
A
S
S
P
G
G
Site 29
S299
E
G
T
K
S
T
A
S
S
P
G
G
P
M
L
Site 30
S300
G
T
K
S
T
A
S
S
P
G
G
P
M
L
T
Site 31
T307
S
P
G
G
P
M
L
T
S
T
P
C
L
N
T
Site 32
T314
T
S
T
P
C
L
N
T
F
F
S
S
L
S
S
Site 33
S320
N
T
F
F
S
S
L
S
S
L
S
V
S
S
S
Site 34
S325
S
L
S
S
L
S
V
S
S
S
V
S
T
Q
R
Site 35
S327
S
S
L
S
V
S
S
S
V
S
T
Q
R
A
L
Site 36
S329
L
S
V
S
S
S
V
S
T
Q
R
A
L
P
G
Site 37
T330
S
V
S
S
S
V
S
T
Q
R
A
L
P
G
S
Site 38
S337
T
Q
R
A
L
P
G
S
R
H
L
G
I
Q
G
Site 39
S350
Q
G
A
Q
L
P
S
S
G
V
F
S
P
T
S
Site 40
S357
S
G
V
F
S
P
T
S
I
S
E
A
S
A
D
Site 41
T365
I
S
E
A
S
A
D
T
L
Q
L
S
N
S
T
Site 42
S369
S
A
D
T
L
Q
L
S
N
S
T
S
N
S
T
Site 43
S371
D
T
L
Q
L
S
N
S
T
S
N
S
T
G
Q
Site 44
S373
L
Q
L
S
N
S
T
S
N
S
T
G
Q
R
S
Site 45
S375
L
S
N
S
T
S
N
S
T
G
Q
R
S
S
Y
Site 46
T376
S
N
S
T
S
N
S
T
G
Q
R
S
S
Y
Y
Site 47
S380
S
N
S
T
G
Q
R
S
S
Y
Y
S
P
F
P
Site 48
S381
N
S
T
G
Q
R
S
S
Y
Y
S
P
F
P
A
Site 49
Y382
S
T
G
Q
R
S
S
Y
Y
S
P
F
P
A
S
Site 50
Y383
T
G
Q
R
S
S
Y
Y
S
P
F
P
A
S
T
Site 51
S384
G
Q
R
S
S
Y
Y
S
P
F
P
A
S
T
S
Site 52
S389
Y
Y
S
P
F
P
A
S
T
S
G
G
Q
S
S
Site 53
S391
S
P
F
P
A
S
T
S
G
G
Q
S
S
P
F
Site 54
S395
A
S
T
S
G
G
Q
S
S
P
F
S
S
P
F
Site 55
S396
S
T
S
G
G
Q
S
S
P
F
S
S
P
F
H
Site 56
S399
G
G
Q
S
S
P
F
S
S
P
F
H
N
F
S
Site 57
S400
G
Q
S
S
P
F
S
S
P
F
H
N
F
S
M
Site 58
S406
S
S
P
F
H
N
F
S
M
V
N
S
L
I
Y
Site 59
S410
H
N
F
S
M
V
N
S
L
I
Y
P
R
E
G
Site 60
Y413
S
M
V
N
S
L
I
Y
P
R
E
G
S
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation