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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Transmembrane protein ENSP00000382582
Full Name:
Transmembrane protein ENSP00000382582
Alias:
Type:
Mass (Da):
125836
Number AA:
1105
UniProt ID:
A8MUB7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
E
I
R
L
E
I
L
T
S
T
G
I
K
Q
K
Site 2
S10
I
R
L
E
I
L
T
S
T
G
I
K
Q
K
K
Site 3
S23
K
K
P
W
P
R
V
S
W
L
G
K
E
K
E
Site 4
S47
I
N
E
I
N
L
L
S
G
K
I
K
K
K
I
Site 5
S56
K
I
K
K
K
I
P
S
L
Q
P
F
L
K
D
Site 6
T101
C
L
K
T
I
P
I
T
E
K
P
K
E
M
I
Site 7
T111
P
K
E
M
I
K
A
T
V
A
S
S
L
R
L
Site 8
Y121
S
S
L
R
L
Y
L
Y
V
S
G
N
G
K
R
Site 9
S152
E
L
K
N
I
L
S
S
K
S
L
S
L
A
G
Site 10
S154
K
N
I
L
S
S
K
S
L
S
L
A
G
R
W
Site 11
S156
I
L
S
S
K
S
L
S
L
A
G
R
W
S
Q
Site 12
S162
L
S
L
A
G
R
W
S
Q
V
I
P
E
E
A
Site 13
S174
E
E
A
V
L
L
P
S
T
E
D
K
E
A
V
Site 14
T223
R
W
H
E
N
V
F
T
S
V
R
S
L
P
Y
Site 15
S250
S
L
I
P
K
C
E
S
V
K
S
R
G
A
L
Site 16
S253
P
K
C
E
S
V
K
S
R
G
A
L
I
S
A
Site 17
S259
K
S
R
G
A
L
I
S
A
F
S
R
D
G
L
Site 18
T271
D
G
L
T
L
A
V
T
L
N
Q
K
D
P
K
Site 19
S296
N
F
V
T
L
C
G
S
L
K
G
C
S
N
K
Site 20
T372
I
P
L
H
P
L
I
T
Y
R
P
Q
Q
F
T
Site 21
T379
T
Y
R
P
Q
Q
F
T
F
Q
D
S
N
N
S
Site 22
S383
Q
Q
F
T
F
Q
D
S
N
N
S
V
D
S
S
Site 23
S386
T
F
Q
D
S
N
N
S
V
D
S
S
A
S
D
Site 24
S389
D
S
N
N
S
V
D
S
S
A
S
D
S
D
P
Site 25
S390
S
N
N
S
V
D
S
S
A
S
D
S
D
P
M
Site 26
S392
N
S
V
D
S
S
A
S
D
S
D
P
M
R
Q
Site 27
S394
V
D
S
S
A
S
D
S
D
P
M
R
Q
R
F
Site 28
S402
D
P
M
R
Q
R
F
S
I
K
A
H
S
R
L
Site 29
Y411
K
A
H
S
R
L
P
Y
L
V
I
S
D
G
Y
Site 30
S430
L
R
F
L
D
S
L
S
P
S
V
H
M
R
S
Site 31
S437
S
P
S
V
H
M
R
S
L
L
L
D
S
T
Q
Site 32
T443
R
S
L
L
L
D
S
T
Q
R
L
E
K
I
Y
Site 33
Y450
T
Q
R
L
E
K
I
Y
Q
S
V
I
L
S
K
Site 34
S452
R
L
E
K
I
Y
Q
S
V
I
L
S
K
P
K
Site 35
S456
I
Y
Q
S
V
I
L
S
K
P
K
G
K
G
L
Site 36
S467
G
K
G
L
N
L
R
S
L
N
S
L
R
S
S
Site 37
S470
L
N
L
R
S
L
N
S
L
R
S
S
L
L
E
Site 38
S473
R
S
L
N
S
L
R
S
S
L
L
E
H
Q
G
Site 39
S474
S
L
N
S
L
R
S
S
L
L
E
H
Q
G
N
Site 40
S484
E
H
Q
G
N
E
S
S
A
D
F
T
V
P
K
Site 41
T488
N
E
S
S
A
D
F
T
V
P
K
F
L
Q
A
Site 42
T514
Q
D
F
E
A
E
E
T
N
E
G
R
H
F
P
Site 43
S538
R
D
D
V
L
C
S
S
M
K
E
G
R
L
E
Site 44
S548
E
G
R
L
E
F
A
S
M
F
D
T
I
H
A
Site 45
T552
E
F
A
S
M
F
D
T
I
H
A
K
D
D
S
Site 46
S559
T
I
H
A
K
D
D
S
E
E
T
D
R
T
I
Site 47
T565
D
S
E
E
T
D
R
T
I
T
E
L
H
S
I
Site 48
T567
E
E
T
D
R
T
I
T
E
L
H
S
I
Q
K
Site 49
S571
R
T
I
T
E
L
H
S
I
Q
K
S
L
L
A
Site 50
T587
W
T
I
G
I
S
K
T
V
T
E
K
N
L
M
Site 51
S624
P
K
L
D
L
V
L
S
K
S
S
R
H
N
A
Site 52
S626
L
D
L
V
L
S
K
S
S
R
H
N
A
W
I
Site 53
Y653
I
H
Y
W
D
I
R
Y
K
Q
D
V
G
H
L
Site 54
T673
N
T
V
K
L
L
L
T
Q
Q
Q
K
G
Q
L
Site 55
S717
I
S
A
S
A
D
G
S
K
I
T
A
Q
D
S
Site 56
T720
S
A
D
G
S
K
I
T
A
Q
D
S
L
V
V
Site 57
S792
R
R
V
P
E
A
D
S
Q
L
T
E
K
M
T
Site 58
S803
E
K
M
T
H
E
A
S
T
V
K
S
L
L
C
Site 59
S807
H
E
A
S
T
V
K
S
L
L
C
H
L
Q
A
Site 60
T826
T
G
D
C
L
N
Q
T
L
E
L
K
S
I
N
Site 61
S831
N
Q
T
L
E
L
K
S
I
N
G
E
E
C
F
Site 62
S842
E
E
C
F
L
L
G
S
Y
E
K
S
V
Q
L
Site 63
S846
L
L
G
S
Y
E
K
S
V
Q
L
W
K
K
A
Site 64
T865
E
E
K
G
G
R
R
T
Y
F
L
Q
I
R
Y
Site 65
Y866
E
K
G
G
R
R
T
Y
F
L
Q
I
R
Y
Y
Site 66
Y878
R
Y
Y
L
S
L
L
Y
C
H
L
Y
S
Y
N
Site 67
Y882
S
L
L
Y
C
H
L
Y
S
Y
N
L
N
D
A
Site 68
S904
A
R
E
I
L
R
W
S
Q
L
P
V
K
E
N
Site 69
T968
L
P
P
L
H
I
K
T
E
Q
S
F
R
L
I
Site 70
S971
L
H
I
K
T
E
Q
S
F
R
L
I
P
L
Q
Site 71
S984
L
Q
H
S
K
V
A
S
V
V
R
D
Q
N
L
Site 72
T996
Q
N
L
S
N
V
W
T
V
E
Y
A
L
E
L
Site 73
T1025
Y
K
L
G
D
W
K
T
S
V
S
I
G
V
A
Site 74
S1041
Q
L
F
C
K
R
D
S
N
F
M
R
S
K
K
Site 75
S1046
R
D
S
N
F
M
R
S
K
K
K
S
L
N
L
Site 76
S1050
F
M
R
S
K
K
K
S
L
N
L
P
L
R
M
Site 77
T1058
L
N
L
P
L
R
M
T
P
A
Q
I
F
Q
E
Site 78
S1076
C
V
L
G
Q
P
A
S
L
E
A
K
N
E
M
Site 79
Y1087
K
N
E
M
G
S
K
Y
K
Q
F
T
G
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation